Eric Escobar
eresc79.bsky.social
Eric Escobar
@eresc79.bsky.social
PhD, Structural Biologist and Protein Engineer with 14+ years of experience engineering molecules.

Thoughts and views here are my own.
A summary of what is happening in science with Trump.

open.spotify.com/episode/56Co...
The War on Science
Science Vs · Episode
open.spotify.com
February 24, 2025 at 4:49 PM
A technical summary of an analysis of the genomic sequence data for the #H5N1 virus from a pediatric case in California that was confirmed by CDC on November 22 was just issued. 1/

www.cdc.gov/bird-flu/spo...
Technical Update: Summary Analysis of the Genetic Sequence of a Highly Pathogenic Avian Influenza A(H5N1) Virus Identified in a Child in California
CDC provides an update on genetic sequencing of the first pediatric case of avian influenza A(H5N1)
www.cdc.gov
December 10, 2024 at 10:22 PM
Dr. Bonnie Henry is providing an update on the #H5N1 case in BC. A thread with the main points. 🧵 1/

www.youtube.com/live/JH76Mi-...
YouTube
Share your videos with friends, family, and the world
www.youtube.com
November 26, 2024 at 7:26 PM
The #CDC has confirmed a human infection with #H5N1 in a child in California. This is the first reported #H5N1 infection in a child in the US. The child reportedly experienced mild symptoms and received flu antivirals.

www.cdc.gov/media/releas...
CDC confirms H5N1 Bird Flu Infection in a Child in California
The Centers for Disease Control and Prevention (CDC) has confirmed a human infection with avian infl
www.cdc.gov
November 22, 2024 at 10:32 PM
I am extremely happy and excited to see that a drug that we developed at Zymeworks was just approved by the FDA.

#biparatopic #bispecific #antibody #Oncology #Immunotherapy #BiparatopicAntibodies #HER2 #InnovationInScience

www.fda.gov/drugs/resour...
FDA grants accelerated approval to zanidatamab-hrii
On November 20, 2024, the FDA granted accelerated approval to zanidatamab-hrii (Ziihera, Jazz Pharmaceuticals, Inc.) for biliary tract cancer.
www.fda.gov
November 22, 2024 at 9:36 PM
Reposted by Eric Escobar
Despite a massive head start, BlueSky has now overtaken Threads in the US 👇
November 19, 2024 at 9:39 PM
New presumptive case of #H5N1 in California.

Like the case in Canada, it is reassuring that family members are testing negative, which suggests that the virus is still not very contagious at the human level.
New from California's health department, now probing with CDC first U.S. case of bird flu in a child

- "not likely infectious"
- "also positive for respiratory viruses"
- "a possible exposure to wild birds"
- "attended daycare with mild symptoms"

www.cdph.ca.gov/Programs/OPA...
November 19, 2024 at 7:11 PM
1/ Update from CDC on #H5N1 dated Nov 18, 2024:

Since April 2024, CDC, has confirmed #H5N1 infections in 52 people in the United States. 21 of these cases were associated with exposure to infected poultry and 30 were associated with exposure to infected dairy cows.

www.cdc.gov/bird-flu/spo...
CDC A(H5N1) Bird Flu Response Update November 18, 2024
CDC provides an update on its response activities related to the multistate outbreak of avian influe
www.cdc.gov
November 18, 2024 at 7:57 PM
Reposted by Eric Escobar
Last week, a teenager in British Columbia contracted H5N1, the first human case acquired in Canada. The BC CDC and and Canadian Food Inspection Agency have released sequences from this infected person and domestic and wild birds sampled in BC, which we've just added to Nextstrain. A thread:
auspice
nextstrain.org
November 17, 2024 at 7:59 PM
Excellent video by @pauloffit.bsky.social and Vincent Racaniello that goes over the history of #H5N1, and available vaccines and treatments:

www.youtube.com/watch?v=hu95...
Beyond the Noise #41: H5N1 influenza virus is unlikely to become a human pandemic
YouTube video by MicrobeTV
www.youtube.com
November 17, 2024 at 6:33 PM
Reposted by Eric Escobar
Reposted by Eric Escobar
The preliminary sequence from the H5N1 human case in British Columbia has been posted and it is not good news. The virus potentially has a quasispecies at HA residue 226 (H3 numbering). This is bad news because we know that mutations at residue 226 can increase binding to human receptors. 1/
November 16, 2024 at 3:19 PM