Emily Liman
@emilyliman.bsky.social
Professor of Neuroscience at USC (Los Angeles), #OTOP proton channels
Plot twist - CryoEM reveals that inhibitors bind to a different site (actually two sites). May displace cholesterol? The discovery of a druggable site will enable the identification of inhibitors and activators of other OTOP channels and propel research into their diverse physiological functions.
October 23, 2025 at 4:52 PM
Plot twist - CryoEM reveals that inhibitors bind to a different site (actually two sites). May displace cholesterol? The discovery of a druggable site will enable the identification of inhibitors and activators of other OTOP channels and propel research into their diverse physiological functions.
2x screens -> good, high affinity inhibitors.
October 23, 2025 at 4:44 PM
2x screens -> good, high affinity inhibitors.
Los Angeles - Stand up for Science!
March 7, 2025 at 4:26 PM
Los Angeles - Stand up for Science!
For your thanksgiving reading pleasure: OTOP1, the sour and ammonium sensor in taste cells, is apically localized, and not restricted to Type III taste cells. www.jneurosci.org/content/earl...
November 30, 2024 at 5:26 PM
For your thanksgiving reading pleasure: OTOP1, the sour and ammonium sensor in taste cells, is apically localized, and not restricted to Type III taste cells. www.jneurosci.org/content/earl...