Elliott Bernard
elliottbernard.bsky.social
Elliott Bernard
@elliottbernard.bsky.social
Biologist 👨‍🔬, baker 🧁, mountain lover ⛰️🥾🎿, boulderer 🧗‍♂️, gay 🏳️‍🌈
And for our latest insights into how NINJ1 is activated and forms membrane-rupturing filaments during cells death, check out our recent preprint.
www.biorxiv.org/content/10.1...
Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling
Plasma membrane rupture (PMR) and the release of cytosolic content are hallmarks of necrotic cell death. The plasma membrane protein ninjurin-1 (NINJ1) actively promotes cell lysis by polymerizing int...
www.biorxiv.org
December 5, 2024 at 6:18 AM
Interested in learning more about NINJ1? My colleagues in the @brozlab.bsky.social, including @ehartenian.bsky.social, wrote a nice review of our current knowledge. www.cell.com/trends/bioch...
www.cell.com
December 5, 2024 at 6:18 AM