Dr. Einar Krogsaeter
einarkrog.bsky.social
Dr. Einar Krogsaeter
@einarkrog.bsky.social
Postdoc in the Krogan/Swaney lab (Gladstone Institutes/UCSF).
Cell biology, neuroscience, subcellular biology.
Studying childhood and adult dementias.
Reposted by Dr. Einar Krogsaeter
APOE4, the strongest genetic risk for Alzheimer’s, disrupts the recycling centers of nerve cells, laying the foundation for toxic protein accumulation. A new study led by Einar Krogsaeter & Danielle Swaney sheds light on early cellular stress in AD.

Read more: www.tandfonline.com/doi/full/10....
Lysosomal proteomics reveals mechanisms of neuronal APOE4-associated lysosomal dysfunction
APOE4 is the primary risk factor for Alzheimer disease (AD). Early AD pathological events first affect the neuronal endolysosomal system, which in turn causes neuronal protein aggregation and cell ...
www.tandfonline.com
November 10, 2025 at 7:36 PM