Edgar V. Lerma 🇵🇭
LightNews LightNews
banner
edgarvlermamd.bsky.social
Edgar V. Lerma 🇵🇭
@edgarvlermamd.bsky.social
1.6K followers 47 following 500 posts
Chicago Sports Fan... Nephrologist by day. My tweets are not medical advice. The views expressed here are my own and not those of my employer
Posts Replies Media Videos
edgarvlermamd.bsky.social
Sibeprenlimab: First @fda.gov approved therapy targeting B cells which produce the abnormal antibodies responsible for #IgAN, addressing the fundamental cause
#Nephpearls #NephSky

#VisualAbstract by @nephroseeker.medsky.social

👉🏼 www.fda.gov/drugs/news-e...

👉🏼 pubmed.ncbi.nlm.nih.gov/41211929/
November 27, 2025 at 2:40 AM
edgarvlermamd.bsky.social
Cholemic Nephropathy aka Cholemic Nephrosis aka Bile Acid/ Bile Cast Nephropathy ca. 2024
#Nephpearls #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/38649215/
November 26, 2025 at 10:43 PM
edgarvlermamd.bsky.social
Testing for the Best Biomarker 🧪 in IgA Nephropathy #IgAN ca. 2025 from @asnpublications.bsky.social
#Nephpearls

Editorial by Dr Richard Lafayette 👉 pubmed.ncbi.nlm.nih.gov/41066174/

#VisualAbstract by @hellokidneymd.bsky.social
👉 pubmed.ncbi.nlm.nih.gov/40924482/
November 16, 2025 at 4:02 AM
edgarvlermamd.bsky.social
BAFF and APRIL represent pre-HIT 1 in #IgAN
#Nephpearls #NephSky

Antigen-driven immune activation within lymphoid tissues leads to the release of BAFF and APRIL, which bind to those receptors and promote B-cell survival and production of IgA

👉🏼 pubmed.ncbi.nlm.nih.gov/38362118/
November 15, 2025 at 8:36 AM
edgarvlermamd.bsky.social
According to ChatGPT, the “four-hit” (or “4-hit”) hypothesis for IgA nephropathy #IgAN was first clearly articulated by Hitoshi Suzuki et al. in their 2011 J. Am. Soc. Nephrol. paper, “The pathophysiology of IgA nephropathy.”
#Nephpearls #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/21949093/
November 15, 2025 at 8:24 AM
edgarvlermamd.bsky.social
Prevalence, Resource Utilization, and Economic Impact of Kidney Function and Proteinuria in Patients With Focal Segmental Glomerulosclerosis (FSGS) ca. 2025 from @juancarlosqvelez.bsky.social
#Nephpearls #FSGS #NephSky

👉 pubmed.ncbi.nlm.nih.gov/41222995/
November 14, 2025 at 3:37 PM
edgarvlermamd.bsky.social
#Nephmadness collectibles 2019-2025
Near Mint condition
#NephSky
November 12, 2025 at 3:59 PM
edgarvlermamd.bsky.social
A Phase 3 Trial of Atacicept in Patients with IgA Nephropathy ca. 2025
#Nephpearls #KidneyWk #NephSky

#VisualAbstract by @nephroseeker.medsky.social @nephjc.bsky.social

👉🏼 pubmed.ncbi.nlm.nih.gov/41196369/
November 9, 2025 at 8:10 PM
edgarvlermamd.bsky.social
Sibeprenlimab in IgA Nephropathy: Interim Analysis of a Phase 3 Trial ca. 2025
#Nephpearls #KidneyWk #NephSky

#VisualAbstract by @nephroseeker.medsky.social @nephjc.bsky.social

👉🏼 www.nejm.org/doi/full/10....
November 9, 2025 at 5:15 PM
edgarvlermamd.bsky.social
My first #KidneyWk was the 33rd Annual Scientific Meeting (including Renal Week) of the American Society of Nephrology, October, 2000 -- Toronto, Ontario, Canada 🇨🇦
#NephSky
November 9, 2025 at 5:03 PM
edgarvlermamd.bsky.social
Your Legacy at #KidneyWk and around the world
#NephSky 🇵🇭🇺🇸
November 9, 2025 at 2:59 AM
edgarvlermamd.bsky.social
#KidneyWk #NephSky
@kidneyboy.bsky.social @rheaultm.bsky.social @jaykoyner.bsky.social
November 8, 2025 at 5:38 PM
edgarvlermamd.bsky.social
#KidneyWk #HTNSecrets #Nephsecrets #NephSky
@hswapnil.medsky.social @kidneyboy.bsky.social @nephrosparks.bsky.social
November 8, 2025 at 5:37 PM
edgarvlermamd.bsky.social
It’s been a pleasure reconnecting with my mentors from @nu-nephrology.bsky.social Drs Daniel Batlle and Robert Rosa
#KidneyWk #NephSky

🙏🏽 I am forever grateful for their mentorship

✍🏼 My first ever publications were with them

pubmed.ncbi.nlm.nih.gov/11689388/

pubmed.ncbi.nlm.nih.gov/15327401/
November 8, 2025 at 2:05 PM
edgarvlermamd.bsky.social
Indications for mineralocorticoid receptor antagonists (MRAs) in the management of cardio-kidney risk
#KidneyWk #Nephpearls #NephSky #Cardiorenal

✅ Check out this resource from @theisn.org
@isnkidneycare.bsky.social

👉 www.theisn.org/initiatives/...
November 8, 2025 at 12:46 PM
edgarvlermamd.bsky.social
Which patients should be on SGLT2 inhibitors (SGLT2i) ⁉️

✅ Check out the SGLT2i Cold 🥶 Map from @theisn.org
#KidneyWk #Nephpearls

👉🏼 www.theisn.org/initiatives/...
November 8, 2025 at 12:04 PM
edgarvlermamd.bsky.social
Immunosuppression in Older Kidney Transplant Recipients: A Randomized Controlled Trial ca. 2025 from @asnpublications.bsky.social
#Nephpearls #KidneyWk #NephSky

journals.lww.com/jasn/fulltex...
November 7, 2025 at 7:04 PM
edgarvlermamd.bsky.social
Is It Time to Consider Population-Based Urine Dipstick Screening for Early Detection of Kidney Disease? ca. 2025 from @kireports.bsky.social @saynanorouzi.bsky.social
#Nephpearls #KidneyWk #NephSky

👉 www.kireports.org/article/S246...
November 7, 2025 at 2:58 PM
edgarvlermamd.bsky.social
CONFIDENCE (Post hoc): Baseline Kidney Function, Albuminuria, and Urine Albumin-Creatinine Ratio Reduction with Finerenone, Empagliflozin, or Both ca. 2025 from
@asnpublications.bsky.social
#Nephpearls #KidneyWk #NephSky

👉 pubmed.ncbi.nlm.nih.gov/41196655/
November 7, 2025 at 1:41 PM
edgarvlermamd.bsky.social
We’re on a mission from God to save kidneys
#KidneyWk #TeamRodbyLerma #NephSky
November 7, 2025 at 12:00 AM
edgarvlermamd.bsky.social
ASN Kidney Health Guidance on Potassium and Phosphorus Food Additives ca. 2025 from @asnpublications.bsky.social
#Nephpearls #KidneyWk #NephSky

👉🏼 pubmed.ncbi.nlm.nih.gov/40965988/
November 6, 2025 at 8:32 PM
edgarvlermamd.bsky.social
You are with us in spirit @hswapnil.medsky.social
#KidneyWk #NephSky
November 5, 2025 at 10:59 PM
edgarvlermamd.bsky.social
I made it to the big board #KidneyWk
Level Up ⬆️🆙
#NephSky
November 5, 2025 at 10:58 PM
edgarvlermamd.bsky.social
Trying to catch up with IgA Nephropathy trials⁉️

Check out ✅ “IgAN: An Overview of the Clinical Trials” ca. 2025 from @kidneymed.bsky.social @alexgr23.bsky.social @saynanorouzi.bsky.social
#Nephpearls #NephSky #KidneyWk #IgAN

👉 pubmed.ncbi.nlm.nih.gov/41050133/
November 5, 2025 at 2:17 PM
edgarvlermamd.bsky.social
B cells undergo a sequential process of maturation and selection and play a crucial role in the adaptive immune system by generating antibodies as a response to foreign antigens
#Nephpearls #KidneyWk #IgAN #NephSky

👉 pubmed.ncbi.nlm.nih.gov/38362118/
November 5, 2025 at 1:37 PM