eClinicalMedicine – The Lancet Discovery Science
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eClinicalMedicine – The Lancet Discovery Science
@eclinicalmed.bsky.social
Gold #openaccess clinical journal, part of The Lancet Discovery Science, influencing clinical practice and strengthening health. IF: 10·0; CiteScore: 17·0.

🌐 https://www.thelancet.com/journals/eclinm/home
Comparative efficacy and safety of CFTR modulators for people with #CysticFibrosis with phe508del mutation: a SR and NMA

Vanzacaftor-tezacaftor-deutivacaftor and elexacaftor-tezacaftor-deutivacaftor were the most effective treatment options in adults

www.thelancet.com/journals/ecl...
#CF #MedSky
November 26, 2025 at 11:31 AM
Omadacycline versus moxifloxacin for community-acquired bacterial #pneumonia (OPTIC-2): a phase 3b RCT

Demonstrates the safety and efficacy of omadacycline in CABP

www.thelancet.com/journals/ecl...
#CAP #CABP #MedSky
November 24, 2025 at 12:12 PM
📢 November issue now online featuring #PalliativeCare, #Endometriosis, #Stroke, #DiabeticNeuropathy, #Melanoma, #mpox, and much more with our editorial on air pollution and child health

…all available #free, #OpenAccess❗️

Read more here: www.thelancet.com/issue/S2589-...

Attribution: Getty
#MedSky
November 21, 2025 at 11:12 AM
Charlotte Rowbottom will be attending ESC Digital Health & AI Summit and welcomes queries from attendees. We are committed to supporting every stage of your publication journey. Learn more about our scope, global reach & impact here: hubs.li/Q03BLdp50
#ESCAIsummit2025
November 19, 2025 at 12:00 PM
Senior Editor Hannah Linne is attending the European Congress on Dermato-Oncology and welcomes queries from attendees. We are committed to supporting you on every stage of your publication journey. Learn more about our journal here: hubs.li/Q03BLdp50
#DermatoOnco2025
November 17, 2025 at 10:32 AM
Our Senior Editor Ben Burlton is attending #EPH2025 and welcomes queries from attendees

Our journals are committed to supporting you on every stage of your publication journey. Learn more about our scope and global reach & impact here: hubs.li/Q03BLdp50

#EUPHAatEPH2025
November 10, 2025 at 1:47 PM
⭐New Series on #ChildhoodCancer in Asia now live!

Published collectively with @lancetchildadol.bsky.social, the 3 papers focus on challenges and opportunities for childhood cancer care in #Asia, which has half the global #paediatric #cancer burden

www.thelancet.com/series-do/childhood-cancer-asia
November 6, 2025 at 12:24 PM
Incidence of non-colorectal/endometrial malignancies in individuals with #LynchSyndrome: a retrospective cohort study

40% of patients had non-CRC/ECs, with 11% of these cases diagnosed prior to undergoing genetic testing

www.thelancet.com/journals/ecl...
#MedSky
November 5, 2025 at 12:05 PM
Prognostic implications of adverse events associated with CAR-T cell therapy: a population-based global observational study

Establishes a systematic mapping of prognostically significant AEs in CAR-T cell therapy

www.thelancet.com/journals/ecl...
#MedSky
November 3, 2025 at 12:36 PM
Surgical margins in breast conserving surgery for DCIS of the breast and clinical outcomes: national audit

Patients with DCIS with histological margins of <2 mm, adjusted for other clinical factors, have significantly worse TTR compared to margins ≥2 mm

www.thelancet.com/journals/ecl...
#MedSky
October 31, 2025 at 11:00 AM
Derivation and external validation of community-acquired #pneumonia subphenotypes in Southeast Asia: a secondary analysis of prospective cohort studies

These subphenotypes may represent unique targets for future #CAP interventional trials

www.thelancet.com/journals/ecl...
#MedSky
October 29, 2025 at 12:08 PM
Real-time risk prediction model for sepsis in patients with acute GI bleeds: development and validation of a monitoring tool

This validated model effectively identifies patients with AGIB at high risk of sepsis, addressing an unmet need in emergency care

www.thelancet.com/journals/ecl...
#MedSky
October 27, 2025 at 12:17 PM
📢 October issue now online featuring #leukaemia, #myeloma, #lymphoma, #heartfailure, #obesity, #CMV, #TBI, and much more with our editorial on a new hope for patients with #HuntingtonsDisease

…all available #OpenAccess❗️

Read here: www.thelancet.com/issue/S2589-...

Attribution: Getty
#MedSky
October 24, 2025 at 11:14 AM
Tackling healthcare providers bias: a systematic review of interventions with implications for inclusive research

Future research could benefit from more rigorous trial designs, standardised metrics for measuring efficacy, and actual provider behaviour

www.thelancet.com/journals/ecl...
#MedSky
October 22, 2025 at 1:15 PM
Prevalence, determinants and prognostic impact of #PolyvascularDisease in patients hospitalised for atherosclerosis in Slovenia

Patients w/ PVD have high overall disease burden, with adverse events increasing in line with number of affected vascular beds

www.thelancet.com/journals/ecl...
#MedSky
October 20, 2025 at 2:03 PM
Health-related quality of life in patients with advanced soft tissue #sarcoma receiving first-line palliative chemotherapy

First-line palliative chemotherapy in advanced STS is associated with significant decrease in GHS, irrespective of tumour response

www.thelancet.com/journals/ecl...
#MedSky
October 17, 2025 at 11:48 AM
Novel avatar-based video-guided acupuncture imagery treatment for chronic low #BackPain: an RCT in the USA

No significant difference was observed between AB-VGAIT and AB-VGTIT; although both interventions yielded significant improvements in pain relief

www.thelancet.com/journals/ecl...
#MedSky
October 15, 2025 at 11:10 AM
📢 New #Podcast: Giulia Zamagni joins Claudia Schaefer to discuss her recent Series of 4 papers from the Italian GBD collaborators providing disease burden estimates and temporal trends for #leukemia, #MultipleMyeloma, #HodgkinLymphoma and NHL in Italy

www.buzzsprout.com/1845316/epis...
October 13, 2025 at 11:45 AM
Oesophageal cancer multidisciplinary tool: a co-designed, externally validated, machine learning tool for oesophageal cancer decision making

Presents a responsibly developed externally validated AI CDSS trained to predict oesophageal cancer MDT decisions

www.thelancet.com/journals/ecl...
#MedSky
October 7, 2025 at 3:41 PM
Using AI and computer vision to detect and monitor unhealthy child-directed food and beverage marketing: a data-driven study

Introduces the first AI-driven approach to identify and categorize child-directed marketing on food and beverage packaging

www.thelancet.com/journals/ecl...
October 6, 2025 at 11:40 AM
Global hospital-based disease management of acute #diverticulitis: a prospective, international cohort study

Reveals significant variation in the management and outcomes of patients presenting to hospital with acute diverticulitis

www.thelancet.com/journals/ecl...
#MedSky
@dalevim.bsky.social
October 3, 2025 at 10:31 AM
Development of a core patient-centred outcome set for adults living with #obesity: a modified delphi-based consensus

Adoption of this standardised outcome set can identify care gaps, monitor outcomes, and evaluate quality of care against global benchmarks

www.thelancet.com/journals/ecl...
#MedSky
October 1, 2025 at 11:55 AM
Global transmission characteristics of #mpox outbreaks: a systematic review and meta-analysis

Each person infected with the mpox virus transmitted it to two others, and the epidemic has continued to spread

www.thelancet.com/journals/ecl...
#MedSky
September 29, 2025 at 12:03 PM
Exploring the temporal relationship between stigma, disease manifestations, and health outcomes in post COVID-19 condition

Persistent PCC-related stigma is a likely contributor to increased disease burden and poor health outcomes over time

www.thelancet.com/journals/ecl...
#LongCovid #MedSky
September 26, 2025 at 9:58 AM
📢 New #Podcast: Karin Modig and Yuge Zhang join Charlotte Rowbottom to discuss their recent work on the disease trajectories of #centenarians in #Sweden

www.buzzsprout.com/1845316/epis...

Read the Article here: www.thelancet.com/journals/ecl...
#MedSky
September 24, 2025 at 12:21 PM