Congrats @jzylicz.bsky.social et al. Very exciting :)

"Firsr Class" - Khruangbin

4/

3/

2/

This is not quite true. Many genes not on either the X or Y chromosomes containing genetic variats have been found to influence sexual development. A person can definitely have a Y chromosome and go through female sex development. Also, the deviation from binary sex is closer to 2% not 0.018%

4/ ...that is not simply determined by whether people carry two X chromosome or an X and a Y chromosome. A lot has happened in genetics since the sex chromosomes were first identified well over a century ago.

3/ Genetically, of course, at fertilization, it is determined what genetic variants one inherits and therefore roughly where on the sex determination spectrum the individual will land. However...

2/ Before sex determination starts at around week 6 post fertilization the embryo is neither phenotypically male nor female. Before sex determination but after the rudimentary gonads have formed, we speak of the "indifferent" gonad as it hasn't started developing in either direction.

Wowm congrats @maudborensztein.bsky.social ! Looking forward to diving in! :)

It is a Nazi salute irrespective of the intention... but I get your point.

"Appears to make" is still not saying it like it is.

@pasquelab.bsky.social exciting! Congrats and thanks! :)