Dylan Murray
@dylantmurray.bsky.social
Molecular Biophysicist. Home chef. Amateur furniture maker. Gardener. DIY specialist when my loved ones permit it.
Reposted by Dylan Murray
🚨 New study: #HSPB8 delays aggregation of TDP43—key in #ALS & #FTD
Could this small heat shock protein, known from rare myopathies, be a therapeutic lead for broader neurodegeneration?
From niche to novel target?
www.biorxiv.org/content/10.1...
#CureHSPB8 #Neurodegeneration #RareDisease
Could this small heat shock protein, known from rare myopathies, be a therapeutic lead for broader neurodegeneration?
From niche to novel target?
www.biorxiv.org/content/10.1...
#CureHSPB8 #Neurodegeneration #RareDisease
Small heat shock protein HSPB8 interacts with a pre-fibrillar TDP43 low complexity domain species to delay fibril formation
The loss of cellular proteostasis through aberrant stress granule formation is implicated in neurodegenerative diseases. Stress granules are formed by biomolecular condensation involving protein-prote...
www.biorxiv.org
April 26, 2025 at 12:59 AM
🚨 New study: #HSPB8 delays aggregation of TDP43—key in #ALS & #FTD
Could this small heat shock protein, known from rare myopathies, be a therapeutic lead for broader neurodegeneration?
From niche to novel target?
www.biorxiv.org/content/10.1...
#CureHSPB8 #Neurodegeneration #RareDisease
Could this small heat shock protein, known from rare myopathies, be a therapeutic lead for broader neurodegeneration?
From niche to novel target?
www.biorxiv.org/content/10.1...
#CureHSPB8 #Neurodegeneration #RareDisease