🇿🇲Vishal C Patel🇬🇧
@drvishalcpatel.bsky.social
Hepatologist🏥@KingsCollegeNHS | Principal Investigator Microbiome🧫🦠 cfDNA🧬@Inst_of_Hep | Reader in Hepatology @kingsmedicine🖋️ | @BoppPtrial💊📈| Home=🇿🇲
🚨 New preprint 🚨
In cirrhosis, oral👄 microbes (Veillonella, Streptococcus) translocate ↘️ gut, carry a collagenase-like enzyme (prtC), disrupt⛓️💥 the intestinal barrier & ⬆️ hepatic fibrosis 🧬
www.biorxiv.org/content/10.1...
In cirrhosis, oral👄 microbes (Veillonella, Streptococcus) translocate ↘️ gut, carry a collagenase-like enzyme (prtC), disrupt⛓️💥 the intestinal barrier & ⬆️ hepatic fibrosis 🧬
www.biorxiv.org/content/10.1...
Microbial oral-gut translocation in advanced chronic liver disease is linked to exacerbation of intestinal barrier dysfunction and hepatic fibrosis
While microbiome perturbations are associated with advanced chronic liver disease (ACLD), microbial disease mechanisms are poorly understood. Using multi-omics analyses of paired saliva and faecal sam...
www.biorxiv.org
September 28, 2025 at 8:06 AM
🚨 New preprint 🚨
In cirrhosis, oral👄 microbes (Veillonella, Streptococcus) translocate ↘️ gut, carry a collagenase-like enzyme (prtC), disrupt⛓️💥 the intestinal barrier & ⬆️ hepatic fibrosis 🧬
www.biorxiv.org/content/10.1...
In cirrhosis, oral👄 microbes (Veillonella, Streptococcus) translocate ↘️ gut, carry a collagenase-like enzyme (prtC), disrupt⛓️💥 the intestinal barrier & ⬆️ hepatic fibrosis 🧬
www.biorxiv.org/content/10.1...
Reposted by 🇿🇲Vishal C Patel🇬🇧
💗 We lit up pink for #OrganDonationWeek.
From 22 September until Sunday 28 September, Hambleden Wing at King's College Hospital, will be pink each evening to raise awareness for #OrganDonationWeek2025
Register your #OrganDonation decision ➡️ tinyurl.com/rzberzrb
#TeamKings #LightUpPink
From 22 September until Sunday 28 September, Hambleden Wing at King's College Hospital, will be pink each evening to raise awareness for #OrganDonationWeek2025
Register your #OrganDonation decision ➡️ tinyurl.com/rzberzrb
#TeamKings #LightUpPink
September 26, 2025 at 11:12 AM
💗 We lit up pink for #OrganDonationWeek.
From 22 September until Sunday 28 September, Hambleden Wing at King's College Hospital, will be pink each evening to raise awareness for #OrganDonationWeek2025
Register your #OrganDonation decision ➡️ tinyurl.com/rzberzrb
#TeamKings #LightUpPink
From 22 September until Sunday 28 September, Hambleden Wing at King's College Hospital, will be pink each evening to raise awareness for #OrganDonationWeek2025
Register your #OrganDonation decision ➡️ tinyurl.com/rzberzrb
#TeamKings #LightUpPink
Reposted by 🇿🇲Vishal C Patel🇬🇧
Really excited that @matthewjdalby.bsky.social is able to share this exciting collaborative study with @drvishalcpatel.bsky.social - its been a long-time coming! We explore how gut #microbiome alterations drive systemic inflammation & immune dysfunction in chronic liver disease (CLD) #LiverDisease
This is my great new preprint with @drvishalcpatel.bsky.social and @halllab.bsky.social. We investigated the gut microbiota in patients with liver disease in which we show an increasing dominance of Enterococcus in the gut of patients with more severe liver disease.
www.medrxiv.org/content/10.1...
www.medrxiv.org/content/10.1...
Pathological expansion of gut microbiome-associated Enterococcus in advanced cirrhosis corresponds with multilevel perturbations of the gut-liver-immune axis
Background Chronic liver disease (CLD) is a progressive condition that, in its advanced stages, leads to cirrhosis with related clinical complications, and can lead to acute-on-chronic liver failure (...
www.medrxiv.org
February 17, 2025 at 5:44 PM
Really excited that @matthewjdalby.bsky.social is able to share this exciting collaborative study with @drvishalcpatel.bsky.social - its been a long-time coming! We explore how gut #microbiome alterations drive systemic inflammation & immune dysfunction in chronic liver disease (CLD) #LiverDisease