Eswar Krishnan
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drugdevelop.bsky.social
Eswar Krishnan
@drugdevelop.bsky.social
16 followers 18 following 28 posts
Immunologist, Rheumatologist and Drug Developer
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drugdevelop.bsky.social
www.drugdevelop.com/p/state-of-t...
State Of The Art in SLE: For Biotech CMOs and CSOs
Founded by Eswar Krishan, MD, a US-based Drug Developer, Immunologist, Internist, and Rheumatologist. All opinions are personal. The information provided here is general guidance and not a substitute ...
www.drugdevelop.com
July 23, 2025 at 11:34 PM
drugdevelop.bsky.social
New frontier in drug development : type 5 Diabetes

www.drugdevelop.com/p/type-5-dia...
Type 5 Diabetes: For CMOs and CSOs
Founded by Eswar Krishan, MD, a US-based Drug Developer, Immunologist, Internist, and Rheumatologist. All opinions are personal. The information provided here is general guidance and not a substitute ...
www.drugdevelop.com
July 7, 2025 at 7:59 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Why I Believe B-cell Engagers are a Game Changer for Lupus
Having spent years as a physician in major tertiary medical centers, including the University of Pittsburgh Medical Center and Stanford University Medical Center, I’ve directly managed the most severe...
open.substack.com
July 6, 2025 at 8:46 AM
drugdevelop.bsky.social
🚀 Exciting Substack post alert! Dive into the future of medicine with my latest piece on CAR-T therapy for autoimmune diseases. Discover groundbreaking insights! 💉📚 #HealthTech #CAR_T #Autoimmune

www.drugdevelop.com/p/car-t-ther...
CAR-T Therapy for Autoimmune Diseases
A guide for the novice
www.drugdevelop.com
July 2, 2025 at 2:00 PM
drugdevelop.bsky.social
Natures Phase zero trials

open.substack.com/pub/drugdeve...
Nature's Phase Zero Trials
A look into the strategic intelligence offered by polyubiquitination disorders that can give your portfolio a decisive edge
open.substack.com
June 29, 2025 at 12:01 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
The Dark Matter of DNA
For decades, they were hidden in plain sight, dismissed as genetic noise.
open.substack.com
June 28, 2025 at 11:59 PM
Reposted by Eswar Krishnan
iasociety.bsky.social
🗓️ Today is National #HIVTestingDay in the US.

This year's theme is “Level up your self-love: check your status.”

📲 Find out where you can get tested and access social resources to help spread the word!
National HIV Testing Day 2025
Love yourself and your partners: Learn your status. Nearly 40% of new HIV cases are transmitted by people who don’t know they’re positive.
www.poz.com
June 27, 2025 at 9:18 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Drug development deep dive: Pharmaceutical grade CBD for inflammatory cardiac diseases
Audio summary for busy executives
open.substack.com
June 27, 2025 at 12:08 AM
drugdevelop.bsky.social
A podcast
Digital Twins for CSOs and CMOs
Founded by Eswar Krishan, MD, a US-based Drug Developer, Immunologist, Internist, and Rheumatologist. All opinions are personal. The information provided here is general guidance and not a substitute ...
open.substack.com
June 24, 2025 at 4:57 PM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Dr Atkins and the Hubris of Medical Establishment
An apology is owed
open.substack.com
June 24, 2025 at 1:15 PM
drugdevelop.bsky.social
Apologies owed

open.substack.com/pub/drugdeve...
Dr Atkins and the Hubris of Medical Establishment
An apology is owed
open.substack.com
June 23, 2025 at 7:13 PM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
High level summary of Cell therapy data presented at EULAR 2025
This report summarizes the key findings from presentations on cell-based therapies, including CAR-T and CAR-NK therapies, at the EULAR 2025 Congress.
open.substack.com
June 21, 2025 at 11:35 PM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
African Americans: Yes for Patriotism. Meh! for Clinical Research participation.
Juneteenth is a day for reflection and understanding for all Americans so that we may strive to be better citizens and a better society.
open.substack.com
June 19, 2025 at 1:39 PM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
A Call to FDA Leadership: Let's Modernize Clinical Trials to Finally Tackle Cancer Prevention
Our shared goal is to reduce the burden of cancer.
open.substack.com
June 16, 2025 at 1:16 PM
drugdevelop.bsky.social
substack.com/@eswarkrishn...
Eswar Krishnan, MD on Substack
substack.com
June 16, 2025 at 8:40 AM
drugdevelop.bsky.social
substack.com/@eswarkrishn...
Eswar Krishnan, MD on Substack
It is not highly likely, yet possible. Like a thermonuclear apocalypse
substack.com
June 16, 2025 at 8:37 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Interferon-𝝰 in the causal pathway of Sjögren Disease
Sjögren's Disease (SjD) is a chronic, systemic immunological disorder with poorly defined initiating and driving immune pathways.
open.substack.com
June 14, 2025 at 7:59 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Japanese Knotweed for Pseudogout
Pseudogout, characterized by acute and painful joint inflammation resulting from the deposition of calcium pyrophosphate (CPP) crystals, can significantly impact quality of life.
open.substack.com
June 14, 2025 at 7:41 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
Crystal Clear Targets: An Actionable Drug Development Strategy for CPPD
Vol. 1 | June 13, 2025
open.substack.com
June 14, 2025 at 7:40 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
CXCR7 : Efficacy of a Novel Agonist and Therapeutic Potential of this Receptor
Vol 1 | June 14, 2025
open.substack.com
June 14, 2025 at 7:40 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
化脓性汗腺炎合并隐匿性关节炎
一篇来自德国的报告
open.substack.com
June 14, 2025 at 7:40 AM
drugdevelop.bsky.social
open.substack.com/pub/drugdeve...
The Tale of Two TLR7/8 Inhibitors at EULAR 2025: Enpatoran and Afimetoran
Data presented today
open.substack.com
June 14, 2025 at 7:39 AM
drugdevelop.bsky.social
open.substack.com/pub/ddjourna...
Vitiligo Skin T Cells Are Prone to Produce Type 1 and Type 2 Cytokines to Induce Melanocyte Dysfunction and Epidermal Inflammatory Response Through Jak Signaling
MARTINS ET. AL.
open.substack.com
June 9, 2025 at 5:30 PM
drugdevelop.bsky.social
open.substack.com/pub/ddjourna...
Zasocitinib: NextGen Allosteric TYK2 Inhibitor—Is the Hype Justified?
This study assessed the TYK2 inhibitory potency and selectivity of zasocitinib versus licensed TYK2 and JAK inhibitors.
open.substack.com
June 8, 2025 at 11:44 PM
drugdevelop.bsky.social
drugdevelop.substack.com/p/interferon...
Interferon Regulatory Factor 7 as drug development target for SLE?
Selectively reduces autoantibody producing plasma cells and downregulates type I interferon without increasing infection risk
drugdevelop.substack.com
June 8, 2025 at 1:16 PM