Senthil Kumar
drsenthil.bsky.social
Senthil Kumar
@drsenthil.bsky.social
MBBS, DNB (Gen.Med.), MRCP (UK), DrNB (Neph.).

Consultant nephrologist, Sree Abirami hospital, Coimbatore, India.

Passion for internal medicine and love for nephrology. Always believe in "Live and let live"
Happy to receive a prize on IgA quiz by Kidney Kolumns from @isn-india.bsky.social at WCN 2025.
Thank you 🙏Dr. Mayuri Trivedi, Dr. Shyam Bansal and Dr. Vineet Behera.
#ISNWCN
February 8, 2025 at 4:02 PM
Doctors shouldn't measure BP 😅

We suck at it. 🤐

There are quite significant pre-requisites for it.

All trials did automated BP recording.
@hswapnil.medsky.social
#ISNWCN
February 8, 2025 at 11:08 AM
February 8, 2025 at 7:56 AM
10-20% variability in eGFR.

40-50% variability in Albuminuria.

Make your clinical judgment accordingly.👌
#ISNWCN
February 8, 2025 at 5:34 AM
@argaiz.bsky.social killing with his teaching skills. It was an amazing session on POCUS and VExUS 👏🔥. Thank you 🙏
#ISNWCN
February 7, 2025 at 12:46 PM
Eisei Sohara talking about importance of genetic testing in CKD.

➡️10-15% of so called ADPKD do not have family history yet have PKD1/2 mutation.

➡️ Other genes involved in PKD (IFT40, CFAP47).

➡️10% of dialysis patients with unknown cause actually have genetic cause.
#ISNWCN
February 7, 2025 at 5:25 AM
Alisporivir, an original antiviral (HepC) drug had shown to increase in mutant trimers in Alport's syndrome acc. to this paper.

It's also a cyclosporin derivative binding to cyclophilin and not to calcineurin.

This was a final DrNB theory question 😑

journals.lww.com/kidney360/fu...
January 21, 2025 at 3:46 AM
My bad. 😀

And yes sir. It gives in most of the important points.
December 30, 2024 at 2:35 PM
👉20 - 30% Na reabsorption in TALH.

50% of that occurs paracellularly😮

➖️NKCC2 probably inhibits paracellular reabsorption as well (Mg and Ca loss).

❓️But why didn't ROMK,the main channel responsible for paracellular reabsorption,inhibitors pick up?

Still wondering if we can increase the arsenal.
December 8, 2024 at 11:31 AM
So GFR >90 ml and ACR < 30 mg/g with with any one of the following criteria for >3 months are classified under G1 A1.

So an ANCA vasculitis or LN with N renal fn and in remission or Bartter’s syndrome with N electrolytes at present are still classified as CKD G1 A1?
#askrenal @askrenal.bsky.social
November 25, 2024 at 8:34 AM
Going through the FLOW trial and found that apart from the white population, where it clearly favours semaglutide, for the rest of the ethnicities, 95%CI lie on both sides. Given that there were 231 Indian patients and Asian population also not giving conclusive results, how to go about it?
November 14, 2024 at 11:21 AM