Chris Rybak
@drsauce.bsky.social
Uyeda Lab, Purdue University
Organic chemist just trying to put two Nickels together.
My business is with Isengard tonight
Organic chemist just trying to put two Nickels together.
My business is with Isengard tonight
Any note on the enolate selectivity in the first step? I’ve used a similar way to make 2-ethyl naphthyridine, but got a 1:1 mixture with 2,3-dimethyl naphthyridine
July 7, 2025 at 8:09 PM
Any note on the enolate selectivity in the first step? I’ve used a similar way to make 2-ethyl naphthyridine, but got a 1:1 mixture with 2,3-dimethyl naphthyridine
Little minigame you need to do so you can get a spectrum
July 5, 2025 at 1:24 AM
Little minigame you need to do so you can get a spectrum
I ordered some from Thermo back in December, finally got it last month. Ordered another bottle, we’ll see how long it takes this time
June 28, 2025 at 3:52 PM
I ordered some from Thermo back in December, finally got it last month. Ordered another bottle, we’ll see how long it takes this time
I think I remember using that for pchem lab like 8 years ago
June 24, 2025 at 6:19 PM
I think I remember using that for pchem lab like 8 years ago
Shakes ain’t bad though
March 8, 2025 at 7:13 AM
Shakes ain’t bad though
Very nice work, Mingxin from our lab was happy to see the advancement of the Ni cyclopropanation chemistry
January 31, 2025 at 2:19 PM
Very nice work, Mingxin from our lab was happy to see the advancement of the Ni cyclopropanation chemistry
What’s the proton look like, a bar code?
January 17, 2025 at 5:12 PM
What’s the proton look like, a bar code?
I’ve grown plenty of crystals for XRD of metal complexes using vapor diffusion and evaporation, but somehow struggle with larger scale organic compounds. I think I’m just less patient for stuff outside the glovebox
January 8, 2025 at 12:32 AM
I’ve grown plenty of crystals for XRD of metal complexes using vapor diffusion and evaporation, but somehow struggle with larger scale organic compounds. I think I’m just less patient for stuff outside the glovebox
Recrysts are a technique I’ve always wanted to improve on. I feel like it’s so intuition based, but I just haven’t cracked it yet
January 7, 2025 at 7:40 PM
Recrysts are a technique I’ve always wanted to improve on. I feel like it’s so intuition based, but I just haven’t cracked it yet
Any place that sells donuts and fried chicken all day is *chefs kiss*
December 28, 2024 at 7:31 AM
Any place that sells donuts and fried chicken all day is *chefs kiss*
I barely had it in me to take one more NMR after cleaning the rotovap bath
December 23, 2024 at 2:35 AM
I barely had it in me to take one more NMR after cleaning the rotovap bath
Two mistakes, a cracked ground glass joint on the bump trap, and letting go before vacuum to fill the cold finger with dry ice
December 23, 2024 at 2:33 AM
Two mistakes, a cracked ground glass joint on the bump trap, and letting go before vacuum to fill the cold finger with dry ice
Is it a bottle you keep on the bench, or some that’s fairly anhydrous?
November 22, 2024 at 3:10 PM
Is it a bottle you keep on the bench, or some that’s fairly anhydrous?
This is what I was going to mention. We’ve got a reaction in our lab that works great if you use the pure boroxine, but not at all with the acid/boroxine mixture
November 22, 2024 at 7:02 AM
This is what I was going to mention. We’ve got a reaction in our lab that works great if you use the pure boroxine, but not at all with the acid/boroxine mixture
That’s what we do in our lab, convert the rest of the alkene to the epoxide
November 8, 2024 at 7:38 AM
That’s what we do in our lab, convert the rest of the alkene to the epoxide