Dr Ronald Ma
drronaldma.bsky.social
Dr Ronald Ma
@drronaldma.bsky.social
clinician, #endocrinology #diabetes, #gestational diabetes, #diabetes in Asia, #PCOS, diabetes advocacy, #NCD, #genomics #precisionmedicine
In the Edwin Bierman Award lecture, Prof Naveed Sattar @Universityof Glasgow
emphasized the role of ectopic fat in pathogenesis of #CVD in diabetes, and the threat of young-onset diabetes in negating the gains in CVD risk reduction over last decade

More here:
doi.org/10.2337/dci23-…
June 29, 2025 at 2:32 AM
Jian Li from Yi lab at Joslin Diabetes Ceter
-CRISP screen identified ALDH3B2 as a key gene to influence pancreatic duct cells to adopt beta-like cell phenotype
June 29, 2025 at 2:29 AM
The 85th scientific sessions of the @amdiabetesassn.bsky.social went by in a flash. A reflection on some of the highlights I attended:

Day 1- Multiomic approaches to decipher mechanisms in T1D and T2D:
Namrata Shukla highlighted role of methylation of RNA in regulation of b-cell function
June 29, 2025 at 2:27 AM
Reposted by Dr Ronald Ma
🔗 doi: 10.1038/s41574-024-01057-w

Insulin resistance and compensatory hyperinsulinaemia, intrinsic to #PCOS and exacerbated by obesity, are major drivers of #metabolic complications and strong determinants of reproductive dysfunction and hyperandrogenaemia in those affected.
November 29, 2024 at 10:28 AM
We validated the JADE risk equations for DM complications in #HongKongDiabetesBiobank, and noted improvement in prediction of #cardiorenal events in T2D using #NT-proBNP. #NT-proBNP alone has good performance for risk stratification
@Diabetologiajnl

link.springer.com/article/10.1...
NT-proBNP improves prediction of cardiorenal complications in type 2 diabetes: the Hong Kong Diabetes Biobank - Diabetologia
Aims/hypothesis N-terminal pro B-type natriuretic peptide (NT-proBNP) is a natriuretic peptide that is strongly associated with congestive heart failure (CHF). The utility of NT-proBNP for prediction ...
link.springer.com
November 22, 2024 at 2:34 PM