This work points towards a promising, non-invasive path for building resilience to stress and stress-related neuropsychiatric disorders. This study was made possible via generous support from the @brightfocus.bsky.social, @alzassociation.bsky.social‬, and the NIH

Tina’s idea turned out to be true, and we were surprised to find that 10Hz sensory stimulation was the most beneficial in males, while 40Hz was the most beneficial in females. This is a fundamentally new approach to mitigate the damaging effects of chronic stress.

Can we experience stress without the damaging effects? Here, we find that non-invasive sensory stimulation at the right frequency induces stress resilience. Tina started this project with a creative idea: can we use sensory stimulation to prevent the damaging effects of chronic stress?

Check out new findings from @TinaFranklin: "Sensory neurostimulation promotes stress resilience with frequency-specificity" on bioRxiv: www.biorxiv.org/content/10.1...

Chronic stress is a major risk factor for neuropsychiatric and neurodegenerative diseases, but for many of us it's unavoidable.

Check out new work by Sara Bitarafan showing that the frequency and duration of audiovisual flicker stimulation are key variables that dictate how flicker affects immune, neuronal, and metabolic genes in the context of Alzheimer’s disease pathology: doi.org/10.1063/5.02....

‪‪@stephmprince.bsky.social‬'s‬ recent paper was included in the Editors’ page “From brain to behaviour”. Check it out here: www.nature.com/collections/...

Editors’ Highlights pages showcase exciting recent papers in an area.

We live in a dynamic world, but we often study navigation as if the world is static. So how do we flexibly adapt in the face of new, pivotal information? @stephmprince.bsky.social addresses just that question in her latest paper: www.nature.com/articles/s41....

This study reveals that chronic 40 Hz flicker enhances hippocampal activity that is essential for memory. This work also demonstrates a new way to evaluate brain stimulation for Alzheimer’s disease, by assessing its effects on memory processes. Full paper is here: www.pnas.org/doi/10.1073/...

Check out our new paper out today in PNAS: “40 Hz sensory stimulation enhances CA3-CA1 coordination and prospective coding during navigation in a mouse model of Alzheimer’s disease”. www.pnas.org/doi/10.1073/...
Led by Abigail Paulson with Lu Zhang and Ashley Prichard @amprichard.bsky.social

Art with the first post is “Gateway to Memory”
by Myriam Wares.

Check out our latest paper today in Nature: “Goal specific hippocampal inhibition gates learning” www.nature.com/articles/s41...
By Nuri Jeong, Xiao Zheng, Abby Paulson, Steph Prince and colleagues.