For anyone interested in doing a PhD at the interface of microbiology and immunology focusing on how AMR pathogens subvert host defenses...you may consider applying to our MRC LID DTP project in which we will explore how Klebsiella hijacks the immune checkpoint PD-L1 mrc-lid.lshtm.ac.uk/apply/

Researchers at @lshtm.bsky.social, led by @josebengoechea.bsky.social, will conduct a £2.2M study funded by UK MRC to investigate how Klebsiella pneumoniae silently colonises the gut before causing deadly infections. 🔬🦠

Read more 👉 bit.ly/4mNSreh

Check out our new #MSc in Biomedical and Clinical Research.

Acquire a broad skill set, selecting a biomedical or clinical focus. Join a vibrant, multi-national community with cutting-edge research projects in #infection & #immunobiology, #AMR, #respiratory #medicine, and more.

DM me for more info

Funded 4-year #PhD in the exciting BBSRC NILAB program. @wwiem-qub.bsky.social

Receive multidisciplinary training, develop #infection models and #AI image analysis to reveal bacterial & viral disease mechanisms & discover new antimicrobials. Fight #AMR

Get in touch!
Details: tinyurl.com/e5k6ptua

New pre print! We establish an ex vivo blood vessel model to investigate the effect of infection on vascular physiology in real time. We show Klebsiella inhibits vasodilation in a T6SS-dependent manner by targeting eNOs. Superb work by @safimicro.bsky.social www.biorxiv.org/content/10.1...

🔊Online now: Klebsiella pneumoniae emerging anti-immunology paradigms: from stealth to evasion

Review by José Bengoechea (@josebengoechea.bsky.social) & colleagues

OA link: www.cell.com/trends/micro...

Last work from the lab in @cp-trendsmicrobiol.bsky.social !
We review the most recent evidence on the strategies deployed by Klebsiella to counteract host defences. www.sciencedirect.com/science/arti... The co-evolution with the immune system has taught the bug a couple of tricks!!!