Junbin Qian
dr-qian.bsky.social
Junbin Qian
@dr-qian.bsky.social
High-resolution cancer biology: chromosomal instability, tumor microenvironment and their therapeutic targeting across multiple cancer types.
MD PhD, Research Professor @ZJU
website: https://www.qian-lab.org
Determining "over-correction" of the single-cell data integration is an unmet need. We found the stably expressed "housekeeping genes" can be used to identify over-correction. Our RBET tool can provide assurance for multi-omics research with big data, big integration. www.nature.com/articles/s42...
Reference-informed evaluation of batch correction for single-cell omics data with overcorrection awareness - Communications Biology
Reference-informed statistical method provides robust guidance on case-specific selection of batch effect correction methods for single-cell omics data with awareness to over-correction, and facilitat...
www.nature.com
April 7, 2025 at 5:36 AM