I feel that this image just about sums it up. For the sake of dogma, deviations from the baseline humanity will be marked as aberrant, but if they are useful and stable enough, they will be sanctioned and put to work.

Out of my tabletop characters, I think this minotaur cleric would suit your style the best.

Red tends to have a bunch of effects like this, though the choice often boils down to "do you want to take big damage now or even bigger damage later?"