dodenim.bsky.social
@dodenim.bsky.social
PhD Student, AI in Oncology at German Cancer Research Center (📍Heidelberg, DE)
Reposted
Spatial transcriptomics holds great promise to understand biological tissue function, but the assignment of transcripts to cells has been a substantial bottleneck.

For this reason, Elyas Heidari, a student in my lab and in @steglelab.bsky.social built segger.

www.biorxiv.org/content/10.1...
March 17, 2025 at 4:19 PM
Reposted
From great collaborations come great things. Excited to share Segger, the solution to segmentation of spatial transcriptomics (ST) data, with the @steglelab.bsky.social and @moritzgerstung.bsky.social labs, spearheaded by the great Andrew Moorman and Elyas Heidari www.biorxiv.org/content/10.1...
Segger: Fast and accurate cell segmentation of imaging-based spatial transcriptomics data
The accurate assignment of transcripts to their cells of origin remains the Achilles heel of imaging-based spatial transcriptomics, despite being critical for nearly all downstream analyses. Current c...
www.biorxiv.org
March 20, 2025 at 11:40 AM
Reposted
A 2023 Review in #ScienceTranslationalMedicine looks at the complex connections between astrocytes and other types of cells in the nervous system, including neurons, oligodendrocytes, and microglia.

Learn more: https://scim.ag/40sLCpB #ScienceMagArchives
Neuroinflammation: An astrocyte perspective
The diverse roles of astrocytes and their cell-cell interactions in neurologic diseases offer opportunities for their therapeutic targeting.
scim.ag
January 11, 2025 at 3:07 PM