Dan Kober
dlkober.bsky.social
Dan Kober
@dlkober.bsky.social
Assistant Prof @ UTSW Biochemistry
Mechanisms of protein homeostasis in lipid metabolism
https://labs.utsouthwestern.edu/kober-lab
Excited to share new work from the lab characterizing substrate recognition & inhibition of site-one protease (S1P). Cool biochemistry lead by talented postbac Ashley Bullington. A very fun and stimulating collaboration with the Zelcer lab!

www.pnas.org/doi/full/10....
April 29, 2025 at 5:59 PM
Highlighting the first paper from my new lab at UTSW! With the Zelcer lab at U Amsterdam, we discovered how a chaperone protein called SPRING licenses S1P to cleave its substrates such as SREBP2. Paper here: pubmed.ncbi.nlm.nih.gov/38977690/
November 12, 2024 at 3:26 AM
Excited to share the the final version of our collaborative manuscript with the Gilles-Gonzalez lab at UTSW Biochemistry
on the structural basis by which oxygen regulates the activity of a bacterial phosphodiesterase! Link: rdcu.be/dZujz
November 12, 2024 at 3:23 AM