Trials within Cohorts (#TwiCs) is an innovative study design that embeds randomized trials directly within ongoing cohort studies.

The Swiss HIV Cohort Study (#SHCS) — a well-established, nationwide cohort — has now implemented the TwiCs design for the first time in Switzerland.

📰 New Article: Effects of Janus kinase inhibitors in adults admitted to hospital with #COVID19: a systematic review and IPD meta-analysis of randomised clinical trials

Findings suggested that JAK inhibitors reduced mortality across all levels of respiratory support

🔗 tinyurl.com/2hprv99v

With over 96% of global trial data on this topic included, this #IPDMA, published in @lancetrespirmed.bsky.social and initiated by #EU-RESPONSE, provides the most comprehensive analysis for JAK inhibitors for adults hospitalized due to #COVID19.

Full article: www.thelancet.com/journals/lan...

We had the pleasure of hosting Prof. @stephensenn.bsky.social in Basel for a public lecture on statistical principles in #RCTs.

Thanks to #PPHS for making it possible — and to Prof. Senn for the inspiring talk and visit!

@unibas.ch @dkf.unibas.ch

🚨Save the date!

March 26th, Prof. @stephensenn.bsky.social will travel to #Basel and give a presentation on methodology and statistics in #RCTs. He will share his insights on why we randomize trials, the value of balance, whether trials should be representative, and much more.

🦠 New publication from COVERALL (Corona Vaccine Platform Trial): Low agreement & frequent invalid controls in 2 SARS-CoV-2 T-cell assays in people with compromised immune function.

This work honours Annette Audigé for her passion & dedication to research!👏🕊️

journals.plos.org/plosone/arti...