Matthias D'hooghe
@dhooghe-group.bsky.social
Full professor of organic chemistry at Ghent University, Belgium. Interested in heterocyclic chemistry and bioactive compound development (bioheterocycles).
Reposted by Matthias D'hooghe
#RRB2026 1-3 June in Leuven
Innovating Today for a Sustainable Tomorrow!
@chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social
Check our latest newsletter mailchi.mp/7e723ddba897...
Innovating Today for a Sustainable Tomorrow!
@chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social
Check our latest newsletter mailchi.mp/7e723ddba897...
October 31, 2025 at 10:14 AM
#RRB2026 1-3 June in Leuven
Innovating Today for a Sustainable Tomorrow!
@chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social
Check our latest newsletter mailchi.mp/7e723ddba897...
Innovating Today for a Sustainable Tomorrow!
@chsteven.bsky.social @pedrofardim.bsky.social @fbwugent.bsky.social @synbioc.bsky.social
Check our latest newsletter mailchi.mp/7e723ddba897...
New paper alert 📢 Our review article on lanthanide nucleotide coordination polymers for sensing applications is published in Coordination Chemistry Reviews: doi.org/10.1016/j.cc... @synbioc.bsky.social @fbwugent.bsky.social @elsevierconnect.bsky.social
September 3, 2025 at 10:32 AM
New paper alert 📢 Our review article on lanthanide nucleotide coordination polymers for sensing applications is published in Coordination Chemistry Reviews: doi.org/10.1016/j.cc... @synbioc.bsky.social @fbwugent.bsky.social @elsevierconnect.bsky.social
Our former @synbioc.bsky.social postdoc Goran Poje presenting his research on harmine-curcuminoid hybrids at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social
September 2, 2025 at 2:24 PM
Our former @synbioc.bsky.social postdoc Goran Poje presenting his research on harmine-curcuminoid hybrids at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social
Our @synbioc.bsky.social PhD student Kato Bredael presenting her research on monocyclic β-lactam antibacterials at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social
September 2, 2025 at 2:22 PM
Our @synbioc.bsky.social PhD student Kato Bredael presenting her research on monocyclic β-lactam antibacterials at the EFMC-ASMC 2025 conference in Porto 😀 @fbwugent.bsky.social @fwovlaanderen.bsky.social @euromedchem.bsky.social
Our review paper on the synthesis and antibacterial properties of C4-functionalized β-lactams is published in @wiley.com: doi.org/10.1002/cmdc... @synbioc.bsky.social @fbwugent.bsky.social @chsteven.bsky.social
May 26, 2025 at 3:38 PM
Our review paper on the synthesis and antibacterial properties of C4-functionalized β-lactams is published in @wiley.com: doi.org/10.1002/cmdc... @synbioc.bsky.social @fbwugent.bsky.social @chsteven.bsky.social
Our PhD student Ulrike Ronse presenting a decade of work on HDAC6 in our group at the Medicinal Chemistry Frontiers conference 2025 in Chicago 😀 @synbioc.bsky.social @fbwugent.bsky.social
May 15, 2025 at 3:57 PM
Our PhD student Ulrike Ronse presenting a decade of work on HDAC6 in our group at the Medicinal Chemistry Frontiers conference 2025 in Chicago 😀 @synbioc.bsky.social @fbwugent.bsky.social
Check out our new paper on 3-imino-β-lactam chemistry, published in J. Org. Chem.: pubs.acs.org/doi/full/10....
@pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social
@fbwugent.bsky.social
@pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social
@fbwugent.bsky.social
May 7, 2025 at 11:17 AM
Check out our new paper on 3-imino-β-lactam chemistry, published in J. Org. Chem.: pubs.acs.org/doi/full/10....
@pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social
@fbwugent.bsky.social
@pubs.acs.org @synbioc.bsky.social @chsteven.bsky.social
@fbwugent.bsky.social
Reposted by Matthias D'hooghe
#SynBioC Proud about our SynBioC team who participated at the Sofico Ghent Half Marathon last Sunday! We love: "Work hard, play hard" @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social
April 1, 2025 at 7:51 AM
#SynBioC Proud about our SynBioC team who participated at the Sofico Ghent Half Marathon last Sunday! We love: "Work hard, play hard" @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social
Reposted by Matthias D'hooghe
Get to know our enthousiastic SynBioC research group @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social
March 26, 2025 at 1:20 PM
Get to know our enthousiastic SynBioC research group @chsteven.bsky.social @dhooghe-group.bsky.social @smangelinckx.bsky.social @thegreenchemlab.bsky.social
Reposted by Matthias D'hooghe
New post: I wrote about a recent PROTAC linker design study that drives home the thoroughness with which you have to experimentally and computationally investigate linker flexibility and properties. It's a great role model for practitioners in the field. medchemash.substack.com/p/the-variet...
The varieties of VHL linker experience
Or why meticulous experimental and computational characterization are integral to good PROTAC design
medchemash.substack.com
March 25, 2025 at 6:49 PM
New post: I wrote about a recent PROTAC linker design study that drives home the thoroughness with which you have to experimentally and computationally investigate linker flexibility and properties. It's a great role model for practitioners in the field. medchemash.substack.com/p/the-variet...
Reposted by Matthias D'hooghe
Significant progress in sustainable chemistry: researchers from the #unibern and the RIKEN Institute have been able to produce organic #molecules using a chemical reaction based on the sustainable metals #sodium and #iron: mediarelations.unibe.ch/media_releas... @evaheviagroup.bsky.social
Sustainable chemistry: producing molecules more environmentally friendly
Researchers from the University of Bern and the RIKEN research institute in Japan have made a significant advance in sustainable chemistry. They have succeeded in producing organic molecules through a...
mediarelations.unibe.ch
March 25, 2025 at 12:29 PM
Significant progress in sustainable chemistry: researchers from the #unibern and the RIKEN Institute have been able to produce organic #molecules using a chemical reaction based on the sustainable metals #sodium and #iron: mediarelations.unibe.ch/media_releas... @evaheviagroup.bsky.social
New paper! Our work on cancer cell cytotoxic benzothiazepanes (part 3), in collaboration with the Rega Institute @kuleuven.bsky.social, is published in J. Heterocyclic Chem.: dx.doi.org/10.1002/jhet... @fbwugent.bsky.social @wiley.com #curcumin
February 10, 2025 at 10:50 AM
New paper! Our work on cancer cell cytotoxic benzothiazepanes (part 3), in collaboration with the Rega Institute @kuleuven.bsky.social, is published in J. Heterocyclic Chem.: dx.doi.org/10.1002/jhet... @fbwugent.bsky.social @wiley.com #curcumin
New Paper Alert! See our joint SynBioC – VIB-CMB work on #HDAC6 ubiquitin-binding domain inhibitors published in Eur. J. Med. Chem. doi.org/10.1016/j.ej... @elsevierconnect.bsky.social, with @rjharding.bsky.social, KU Leuven, @csbugent.bsky.social, K. Van Hecke. @fbwugent.bsky.social
January 17, 2025 at 9:39 AM
New Paper Alert! See our joint SynBioC – VIB-CMB work on #HDAC6 ubiquitin-binding domain inhibitors published in Eur. J. Med. Chem. doi.org/10.1016/j.ej... @elsevierconnect.bsky.social, with @rjharding.bsky.social, KU Leuven, @csbugent.bsky.social, K. Van Hecke. @fbwugent.bsky.social
Reposted by Matthias D'hooghe
This #OrgLett cover by Guillermo Correa Otero demonstrates human error in mass spec report checking. Instead use CheckAMM!
Editorial by EIC Marisa Kozlowski introducing CheckAMM:
pubs.acs.org/doi/10.1021/...
What @christmann.bsky.social found checking AMM reports:
pubs.acs.org/doi/10.1021/...
Editorial by EIC Marisa Kozlowski introducing CheckAMM:
pubs.acs.org/doi/10.1021/...
What @christmann.bsky.social found checking AMM reports:
pubs.acs.org/doi/10.1021/...
January 13, 2025 at 7:05 PM
This #OrgLett cover by Guillermo Correa Otero demonstrates human error in mass spec report checking. Instead use CheckAMM!
Editorial by EIC Marisa Kozlowski introducing CheckAMM:
pubs.acs.org/doi/10.1021/...
What @christmann.bsky.social found checking AMM reports:
pubs.acs.org/doi/10.1021/...
Editorial by EIC Marisa Kozlowski introducing CheckAMM:
pubs.acs.org/doi/10.1021/...
What @christmann.bsky.social found checking AMM reports:
pubs.acs.org/doi/10.1021/...
Reposted by Matthias D'hooghe
Researchers spend approximately 45% of their time on administrative activities related to #grants rather than actual #research. The current #competition in research #funding has significant drawbacks; evidence-based improvements of the funding system are required: www.pnas.org/doi/10.1073/...
The costs of competition in distributing scarce research funds | PNAS
Research funding systems fundamentally influence how science operates. This paper
aims to analyze the allocation of competitive research funding fr...
www.pnas.org
December 22, 2024 at 7:05 PM
Researchers spend approximately 45% of their time on administrative activities related to #grants rather than actual #research. The current #competition in research #funding has significant drawbacks; evidence-based improvements of the funding system are required: www.pnas.org/doi/10.1073/...
Teambuilding activity at the Christmas market in Ghent 😀
December 11, 2024 at 9:53 AM
Teambuilding activity at the Christmas market in Ghent 😀
Congratulations to our new SynBioC doctor Katarina Magdalenic for the excellent work on curcuminoids, and many thanks to Prof. Zrinka Rajic from the University of Zagreb for acting as an external jury member!
December 9, 2024 at 12:56 PM
Congratulations to our new SynBioC doctor Katarina Magdalenic for the excellent work on curcuminoids, and many thanks to Prof. Zrinka Rajic from the University of Zagreb for acting as an external jury member!
It was a pleasure to host Prof. Annette Bayer from the Artic University of Norway today, who gave a very inspiring lecture about stereoselective CO2 fixation and beta-lactamase inhibitor design
November 25, 2024 at 7:20 PM
It was a pleasure to host Prof. Annette Bayer from the Artic University of Norway today, who gave a very inspiring lecture about stereoselective CO2 fixation and beta-lactamase inhibitor design