Devani Romero Picazo
banner
devaropica.bsky.social
Devani Romero Picazo
@devaropica.bsky.social
Postdoc at @DaganLab studying plasmid evolution, microbial pangenomes and adaptation to plant-associated lifestyle. CAU, Kiel.
This suggests that domesticated plasmids in Pantoea arose from large ancestral plasmids that experienced genome streamlining, similar to that observed in endosymbionts.
November 14, 2025 at 9:21 AM
By using phylogenetics, we show that most genes with homologs in both the plasmid and the chromosome have different evolutionary origins. Moreover, we identify related plasmids outside of the genus that are rather large.
November 14, 2025 at 9:21 AM
Devani Romero Picazo
Interestingly, plasmid LPP-1 harbours genes that are core in the genus pangenome. Most of these genes encode for transcriptional regulators, suggesting the integration of the plasmid in the host's regulatory network.
November 14, 2025 at 9:21 AM
These domesticated plasmids have diversified within the genus, where plasmid groups -with different gene content and sizes- coincide with main speciation events.
November 14, 2025 at 9:21 AM
We show that the genomes of plant-associated Pantoea comprise two domesticated plasmids that are inherited vertically, just like chromosomes. We prove that the largest plasmid (LPP-1) replicates synchronously with the chromosome.
November 14, 2025 at 9:21 AM