Depresh Mode with John Moe
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depreshmode.bsky.social
Depresh Mode with John Moe
@depreshmode.bsky.social
1.4K followers 76 following 160 posts
An award-winning weekly mental health podcast about living with complicated minds, featuring musicians, comics, researchers, experts, authors, and actors.
https://maximumfun.org/podcasts/depresh-mode/
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depreshmode.bsky.social
This week, we examine the dramatic cuts to SAMHSA, the gov't agency in charge of supporting addiction, suicide prevention, and mental health programs receiving federal funding. More than half the employees are gone since January. Huge news story and it's personal.
maximumfun.org/episodes/dep...
November 10, 2025 at 4:06 PM
depreshmode.bsky.social
SAD (seasonal affective disorder) is a term that's gone out of fashion. Now: major depressive disorder with a seasonal pattern, which almost forms the acronym MUD WASP. Learn what a top mental health expert says about how to make winter bearable as mud wasps descend.
maximumfun.org/episodes/dep...
November 3, 2025 at 4:35 PM
depreshmode.bsky.social
Now there's a title:
HOW I KNOW WHITE PEOPLE ARE CRAZY and Other Stories.
We welcome author Dr. Jonathan Mathias Lassiter for a fascinating talk on the mental health problem that whiteness presents for everyone, regardless of race. Really fascinating discussion.

maximumfun.org/episodes/dep...
October 27, 2025 at 6:23 PM
depreshmode.bsky.social
Really fascinating and wide-ranging conversation with P.E. Moskowitz @pempem.bsky.social this week about drugs, trauma, and whether the problems you're having are you having an illness or you living in a sick world. You'll want to hear this one.
maximumfun.org/episodes/dep...
October 13, 2025 at 5:26 PM
depreshmode.bsky.social
When you think of people with depression and anxiety, you don't think of folks like Kendall Toole. Entrepreneur, former star instructor on Peloton, confident, poised, in great shape, former USC cheerleader. Mental illness doesn't care. It'll get you anyway.
maximumfun.org/episodes/dep...
October 6, 2025 at 5:00 PM
depreshmode.bsky.social
Anne was 59. Had been hospitalized for depression, received rounds of ECT, survived an emotionally abusive childhood.
Then she went to a Springsteen show. Her *first ever* concert. It changed everything. So she followed Bruce to Australia.
Hell of a story this week.
maximumfun.org/episodes/dep...
September 29, 2025 at 3:24 PM
depreshmode.bsky.social
A couple years ago, singer/songwriter Emma Swift @emmaswiftsings.bsky.social had a nervous breakdown & psychotic episode. She was hospitalized for several weeks. Then got better and wrote some amazing songs. She walks us through all of it in a fascinating interview.
maximumfun.org/episodes/dep...
September 22, 2025 at 6:10 PM
depreshmode.bsky.social
People are using AI bots like ChatGPT, losing touch with reality, and ending up hospitalized or dead. It's being called AI psychosis, which is a pretty alarming name but seems pretty accurate. This week's show explores it. Important and disturbing listen.
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Person being sucked into a computer illustration from Stat News
September 15, 2025 at 1:53 PM
depreshmode.bsky.social
Delighted to welcome Alex Edelman to the show this week. Emmy and Tony winner for his one-man show Just For Us and one of the stars of The Paper. We talk about those shows, psychic damage, ADHD, grief and so much more.
maximumfun.org/episodes/dep...
September 8, 2025 at 3:08 PM
depreshmode.bsky.social
What is your clutter, your design, the overall THING of your home design doing to your mental health? We have Dr. Beverly Walpole to talk about the way you live and the relationship to the way your mind works.

maximumfun.org/episodes/dep...
September 1, 2025 at 10:28 PM
depreshmode.bsky.social
Our latest newsletter, totally free to subscribe, is now available.
Big news on the power of lithium plus why Bill Hader wasn't on the SNL 50th anniversary, people doing amazing things with yo-yos and dance moves, and tennis and Broadway stars putting you to sleep.
open.substack.com/pub/johnmoe/...
August 25, 2025 at 1:52 PM
depreshmode.bsky.social
Denise Winkelman is a:
- comedian with a new debut special
- transgender lesbian woman
- former pro wrestler
- person with chronic pain and fibromyalgia
- fascinating human being with an amazing story
- our guest on the podcast this week

You'll want to hear this one.

maximumfun.org/episodes/dep...
August 25, 2025 at 1:35 PM
depreshmode.bsky.social
Our show this week features Ashly Burch, acclaimed actor, maker, swell person. She has a new YouTube show about mental health featuring puppets and swears. We discuss ANXIETY, EMDR, trauma, and, you know, puppets.
maximumfun.org/podcasts/dep...
I'm glad she's here. And I'm happy too.
August 18, 2025 at 3:18 PM
depreshmode.bsky.social
I can't summarize our amazing interview with author and comedian Tiffany Jenkins this week so here are things that come up:
Anxiety
Addiction
Stealing a cop's guns
Selling them for drugs
Passive suicidal ideation
Comedy!
Refusing to give kids grapes b/c choking terror

maximumfun.org/episodes/dep...
August 11, 2025 at 4:48 PM
depreshmode.bsky.social
Latest edition of our FREE Depresh Mode newsletter has alarming information on the FDA's approach to SSRIs, intriguing developments on mandatory mental health screenings in public schools, and how to upload a picture to a bird and then download it from a bird.
johnmoe.substack.com/p/oh-dear-th...
August 4, 2025 at 5:13 PM
depreshmode.bsky.social
Aaron Foster had an abusive father, his brother with schizophrenia died by suicide, and he's been diagnosed with depression. He's owned two restaurants and had a successful 20-year art career. Now in his 50s, he's decided to be a full-time comedian. He's very funny.
maximumfun.org/episodes/dep...
August 4, 2025 at 4:52 PM
depreshmode.bsky.social
Aaron Taylor had an abusive father, his brother with schizophrenia died by suicide, and he's been diagnosed with depression. He's owned two restaurants and had a successful 20-year art career. Now in his 50s, he's decided to be a full-time comedian. He's very funny. maximumfun.org/episodes/dep...
August 4, 2025 at 3:42 PM
depreshmode.bsky.social
Nurse Blake started making comedy videos to manage the stress and burnout of his nursing job. Then they went viral and it turned into a comedy career. We talk about that, his experiences as a teenager in gay "conversion therapy", panic attacks and more.
maximumfun.org/episodes/dep...
July 28, 2025 at 5:35 PM
depreshmode.bsky.social
We didn't expect to be approached about having Gavin Rossdale on our show but it made more sense when we learned that Bush's new album is a lot about mental health. He shared his thoughts about music, trauma, recovery, and the rewards of full emotional experiences.
maximumfun.org/episodes/dep...
July 21, 2025 at 2:32 PM
depreshmode.bsky.social
If you can't sleep, you know it's not just a physical thing, it's mental and emotional too.
We dive into the links between insomnia, depression, anxiety, shame, and so much more.
@jennifersenior.bsky.social of @theatlantic.com, herself an insomniac, joins us.
maximumfun.org/episodes/dep...
July 14, 2025 at 2:02 PM
depreshmode.bsky.social
Very different show this week. It features a talk w/ former journalist Brandon Stickney who lost everything and ended up in prison due to a vicious substance use disorder and bad decisions.
Hear what mental health is like behind bars and how he found hope and healing.
maximumfun.org/episodes/dep...
July 7, 2025 at 4:02 PM
depreshmode.bsky.social
Revisiting one of our favorite episodes this week with @mariabamford.bsky.social. Delightful, smart, fierce.

maximumfun.org/episodes/dep...
June 30, 2025 at 5:30 PM
depreshmode.bsky.social
Ginny & Georgia is one of the top shows on Netflix and we’ve been impressed by how they’ve handled stuff like depression, trauma response, and self-harm. This week, a talk with Sarah Lampert, creator of the series, about the steps they take to tell more honest stories.
maximumfun.org/episodes/dep...
June 24, 2025 at 3:32 AM
depreshmode.bsky.social
Ginny & Georgia is a huge hit show and it tackles mental health in a refreshingly clear-eyed and insightful way. On our podcast this week, a talk with show creator Sarah Lampert about the steps they take to get it right.
maximumfun.org/episodes/dep...
June 23, 2025 at 11:15 AM
depreshmode.bsky.social
Our newest episode features the singer-songwriter Alexandra Savior in an honest conversation about her bipolar disorder, the manic episode she's coming down from, her psychosis, depression, and healing.
I appreciate her vulnerability in this memorable interview.
maximumfun.org/episodes/dep...
June 16, 2025 at 12:25 PM