Deirdre Logsdon, PhD
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deirdrelogsdon.bsky.social
Deirdre Logsdon, PhD
@deirdrelogsdon.bsky.social
270 followers 370 following 5 posts
Embryology | Blastoids| Implantation | Trophoblast Development and Function | Infertility | Postdoc | Brumbaugh Lab
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Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
Pub of the Month! 📄💜

This month’s feature: “Comparative analysis of human and mouse ovaries across age” from the Laird Laboratory @ucsanfrancisco.bsky.social

Celebrating the research (and researchers!) moving science forward. 🔬🥼✨

#ReproRocks #WinRS #NewPublication #Research #SSR #Science
October 31, 2025 at 5:59 PM
Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
Here’s to unraveling the mysteries of reproduction one (spooky) experiment at a time! 👻🧪
October 31, 2025 at 6:00 PM
deirdrelogsdon.bsky.social
SOOOOO proud of our amazing grad student Mika! 👏 👏👏Congrats to
@distefanolab.bsky.social
and @brumbaugh-lab.bsky.social for their manuscript describing how biomolecular condensates direct cell fate!
@natbiotech.nature.com www.nature.com/articles/s41...
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
www.nature.com
October 28, 2025 at 3:38 PM
Reposted by Deirdre Logsdon, PhD
springernature.com
Functional human eggs have been generated from skin cells in a proof-of-concept study in @natcomms.nature.com. The technique could offer a new path to treating infertility, though more research is needed before clinical use.

#devbio

www.nature.com/articles/s41...
Induction of experimental cell division to generate cells with reduced chromosome ploidy - Nature Communications
Researchers induced ploidy reduction in human oocytes generated by somatic cell nuclear transfer, enabling fertilization and embryo development with integrated somatic and sperm chromosomes, highlighting a proof-of-concept for in vitro gametogenesis.
www.nature.com
October 1, 2025 at 7:17 PM
deirdrelogsdon.bsky.social
www.nature.com/articles/d41...
‘Congress has your back’: US senators tell scientists they want to protect NIH budget
Senate budget bill includes small increase for the health-research agency — but faces a long road before being signed into law.
www.nature.com
August 4, 2025 at 2:31 PM
deirdrelogsdon.bsky.social
SSR annual meeting was such a blast. Didn’t realize how much I needed my repro friends!
@ssrwinrs.bsky.social
#reprorocks #womeninSTEM
August 4, 2025 at 2:30 PM
Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
Going to the SSR annual meeting and need childcare support? Apply for a childcare grant through WinRS! #momsinstem #happymothersday
May 12, 2025 at 5:35 PM
Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
Attention SSR Annual Meeting attendees:
Don't miss registration for the Lunch and Learn session with Dr. Kelly Diggs to sharpen up your mentoring skills!
#reprorocks #womeninstem
May 29, 2025 at 8:37 PM
deirdrelogsdon.bsky.social
Happy Pi Day y’all!
March 14, 2025 at 10:02 PM
Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
#womenshistorymonth #womeninstem
March 4, 2025 at 10:16 PM
Reposted by Deirdre Logsdon, PhD
ssrwinrs.bsky.social
Listen to 2024 Roger V Short Medal Awardee, Dr. Francesca Duncan, discuss ovarian aging and give trainees a bit of her wisdom on the latest SSR podcast! 👏👏👏
#womeninSTEM #reprorocks
Listen to the full episode here 👇https://www.buzzsprout.com/1786803/episodes/16143433
January 16, 2025 at 4:41 PM
deirdrelogsdon.bsky.social
I’m SO proud of my postdoc lab for publishing their first Brumbaugh Lab paper in @NatureCellBio today! Check out how altered H3K36 methylation impacts intestinal cell plasticity 👇
www.nature.com/articles/s41...

Congratulations @Brumbaugh_JB 🥳
H3K36 methylation regulates cell plasticity and regeneration in the intestinal epithelium - Nature Cell Biology
Pashos et al. show that H3K36 methylation maintains intestinal epithelial fate commitment, whereas its suppression, which is also observed upon injury, induces a plastic state and expression of genes ...
www.nature.com
January 9, 2025 at 12:11 AM
Reposted by Deirdre Logsdon, PhD
biologists.bsky.social
Wenli Fan et al. leverage conditional mouse knockouts to explore the link between placental problems and congenital heart defects, showing that SLC25A1 regulates trophoblast differentiation and placental development to safeguard embryonic heart formation. 🐭🫀 https://bit.ly/4g372OU #DevBio
Working model of the impact of Slc25a1 deficiency on placental and embryonic cardiac development. In the normal placenta (left), SLC25A1 facilitates the transport of citrate from mitochondria to the cytoplasm. Citrate is converted into acetyl-CoA, which is essential for maintaining H3K27ac and promoting the differentiation of trophoblast cells. Trophoblast cells secrete PSG proteins, supporting normal placental and embryonic heart development. In the absence of Slc25a1 (right), citrate cannot be transported from mitochondria to the cytoplasm, resulting in a reduction in acetyl-CoA levels. This leads to reduced deposition of H3K27ac at the promoter and enhancer regions of key factors involved in trophoblast differentiation and Psg genes, thereby affecting the expression levels of these genes and causing abnormal placental development, which in turn leads to conotruncal defects and thinner ventricular walls in mouse embryonic hearts.
November 27, 2024 at 2:38 PM