DEEP-DV FOR5200
@deep-dv-for5200.bsky.social
Official account of the DFG research unit FOR5200 DEEP-DV
Disrupt–Evade–Exploit: Gene expression and host response programming in DNA virus infection
Disrupt–Evade–Exploit: Gene expression and host response programming in DNA virus infection
Perturbation of centromeres by herpesviruses triggers centromeric DNA amplification via translesion DNA synthesis that is detected by nuclear cGAS. This work reveals an unexpected role of centromeres in immune activation beyond mitosis.
authors.evlsevier.com/c/1lCC7L7PXu...
authors.evlsevier.com/c/1lCC7L7PXu...
June 18, 2025 at 2:51 PM
Perturbation of centromeres by herpesviruses triggers centromeric DNA amplification via translesion DNA synthesis that is detected by nuclear cGAS. This work reveals an unexpected role of centromeres in immune activation beyond mitosis.
authors.evlsevier.com/c/1lCC7L7PXu...
authors.evlsevier.com/c/1lCC7L7PXu...
The Bosse lab has developed a structure prediction database covering the proteomes of all human Herpesviruses. A description of their database, HerpesFolds, & insights it has revealed about new protein families published in NatCom mun. Have a look at the interactive website at www.herpesfolds.org!
November 29, 2024 at 5:15 PM
The Bosse lab has developed a structure prediction database covering the proteomes of all human Herpesviruses. A description of their database, HerpesFolds, & insights it has revealed about new protein families published in NatCom mun. Have a look at the interactive website at www.herpesfolds.org!