Stephen Decker, PhD
@decker-st.bsky.social
Dad | Physiologist | Postdoc with Katsu Funai at the University of Utah
Researching (and parenting a child with) X-linked Alport Syndrome & Kidney bionergetics
Mitochondrial biology meets kidney disease
Views my own
Researching (and parenting a child with) X-linked Alport Syndrome & Kidney bionergetics
Mitochondrial biology meets kidney disease
Views my own
Time to play Figure Roulette with Word for another grant proposal...
November 12, 2025 at 7:07 PM
Time to play Figure Roulette with Word for another grant proposal...
Also my favorite poster companion 💜
@asnpublications.bsky.social
@alportuk.bsky.social
#ASN #KidneyWeek #AlportSyndrome
@asnpublications.bsky.social
@alportuk.bsky.social
#ASN #KidneyWeek #AlportSyndrome
November 7, 2025 at 4:57 PM
Also my favorite poster companion 💜
@asnpublications.bsky.social
@alportuk.bsky.social
#ASN #KidneyWeek #AlportSyndrome
@asnpublications.bsky.social
@alportuk.bsky.social
#ASN #KidneyWeek #AlportSyndrome
"Your claim is denied because congenital disorders aren't covered after age 26"
Oh, because my cleft lip and palate magically took care of themselves once I turned 26. How stupid of me.
Oh, because my cleft lip and palate magically took care of themselves once I turned 26. How stupid of me.
November 6, 2025 at 6:30 PM
"Your claim is denied because congenital disorders aren't covered after age 26"
Oh, because my cleft lip and palate magically took care of themselves once I turned 26. How stupid of me.
Oh, because my cleft lip and palate magically took care of themselves once I turned 26. How stupid of me.
Heading out to #KidneyWeek with my faithful travel companion!
I'm so honored to have been awarded a People's Choice Award for the @asnpublications.bsky.social Basic Science Forum! This will be such an exciting trip!
I'm so honored to have been awarded a People's Choice Award for the @asnpublications.bsky.social Basic Science Forum! This will be such an exciting trip!
November 5, 2025 at 12:59 PM
Heading out to #KidneyWeek with my faithful travel companion!
I'm so honored to have been awarded a People's Choice Award for the @asnpublications.bsky.social Basic Science Forum! This will be such an exciting trip!
I'm so honored to have been awarded a People's Choice Award for the @asnpublications.bsky.social Basic Science Forum! This will be such an exciting trip!
Somebody was upset that the mermaids couldn't go to daycare, so I told her that they would come to work with me and be my helpers today
October 27, 2025 at 6:22 PM
Somebody was upset that the mermaids couldn't go to daycare, so I told her that they would come to work with me and be my helpers today
4 came too fast 😭
October 25, 2025 at 11:30 PM
4 came too fast 😭
Today in the lab:
My coworkers are mind-blown that I have aphantasia.
My coworkers are mind-blown that I have aphantasia.
October 21, 2025 at 7:07 PM
Today in the lab:
My coworkers are mind-blown that I have aphantasia.
My coworkers are mind-blown that I have aphantasia.
So exciting to share this! What started off as a "let's see what happens" project has finally come full circle. I can't wait to see this project reviewed and in press!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
A Platform for Mitochondrial Profiling in Enriched Kidney Segments Under Thermodynamic Control in Mice and Humans
Mitochondrial function varies widely across kidney nephron segments, yet conventional approaches lack the resolution and control needed to assess cell-type-specific bioenergetics in situ. We present a...
www.biorxiv.org
October 18, 2025 at 2:22 PM
So exciting to share this! What started off as a "let's see what happens" project has finally come full circle. I can't wait to see this project reviewed and in press!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Hy heart is broken. Thank you, thank you for everything for me, and countless others. You gave us all a chance to be normal.
Ernest Cronin Obituary - Stafford, TX
Celebrate the life of Ernest Cronin, leave a kind word or memory and get funeral service information care of Earthman Southwest Funeral Home.
www.dignitymemorial.com
October 13, 2025 at 2:35 PM
Hy heart is broken. Thank you, thank you for everything for me, and countless others. You gave us all a chance to be normal.
Reposted by Stephen Decker, PhD
The Center for Metabolic Health brings together researchers to tackle major diseases like diabetes and heart failure by focusing on a central factor: metabolism.
Discover more about this interdisciplinary hub at University of Utah Health: https://www.nature.com/articles/d42473-025-00227-2
Discover more about this interdisciplinary hub at University of Utah Health: https://www.nature.com/articles/d42473-025-00227-2
Metabolism as the next biomedical frontier
From harnessing early-life microbes to protect against diabetes, to targeting cardiac metabolism in heart failure, a new hub is proving that metabolism is a common thread across diseases, and the next frontier in biomedical discovery.
www.nature.com
October 1, 2025 at 8:03 PM
The Center for Metabolic Health brings together researchers to tackle major diseases like diabetes and heart failure by focusing on a central factor: metabolism.
Discover more about this interdisciplinary hub at University of Utah Health: https://www.nature.com/articles/d42473-025-00227-2
Discover more about this interdisciplinary hub at University of Utah Health: https://www.nature.com/articles/d42473-025-00227-2
Back to 0. I wish my Chrome tabs could say the same thing...
I'm one of those people that can't have unread emails in my inbox. Right now I have 34 unread emails and counting, and it's peaking my anxiety.
September 19, 2025 at 9:40 PM
Back to 0. I wish my Chrome tabs could say the same thing...
I'm one of those people that can't have unread emails in my inbox. Right now I have 34 unread emails and counting, and it's peaking my anxiety.
September 19, 2025 at 2:16 PM
I'm one of those people that can't have unread emails in my inbox. Right now I have 34 unread emails and counting, and it's peaking my anxiety.
I'm such a nerd running deep learning scripts on Colab and walking between buildings as close and as fast as possible with my laptop open so that I maintain my wifi connection
September 12, 2025 at 9:13 PM
I'm such a nerd running deep learning scripts on Colab and walking between buildings as close and as fast as possible with my laptop open so that I maintain my wifi connection
I am thrilled to share that my abstract focusing on novel humanized mouse models of X-linked Alport Syndrome has been selected as a finalist for the Iozzo Trainee Award, as well as a recipient of a Travel Award to the American Society for Matrix Biology biannual meeting.
August 24, 2025 at 6:50 PM
I am thrilled to share that my abstract focusing on novel humanized mouse models of X-linked Alport Syndrome has been selected as a finalist for the Iozzo Trainee Award, as well as a recipient of a Travel Award to the American Society for Matrix Biology biannual meeting.
It happened. I got into an argument with AI this morning...
August 19, 2025 at 3:12 PM
It happened. I got into an argument with AI this morning...
If it walks like a dog and rolls in the dirt like a dog...
Then it's a stray dog and I can take it home as my new ESA, right?
Then it's a stray dog and I can take it home as my new ESA, right?
August 4, 2025 at 6:43 PM
If it walks like a dog and rolls in the dirt like a dog...
Then it's a stray dog and I can take it home as my new ESA, right?
Then it's a stray dog and I can take it home as my new ESA, right?
I always make it known that I'm a reviewer for a paper, but part of me is always afraid that I will get confronted and somebody will try to beat me up and take my lunch money at conferences.
a man in a purple shirt is standing in a field with two other men .
ALT: a man in a purple shirt is standing in a field with two other men .
media.tenor.com
July 24, 2025 at 12:38 AM
I always make it known that I'm a reviewer for a paper, but part of me is always afraid that I will get confronted and somebody will try to beat me up and take my lunch money at conferences.
Birthday brisket.
At least I feel like I have a solid plan B if the NIH completely dies...
At least I feel like I have a solid plan B if the NIH completely dies...
July 20, 2025 at 4:54 AM
Birthday brisket.
At least I feel like I have a solid plan B if the NIH completely dies...
At least I feel like I have a solid plan B if the NIH completely dies...
I think the algorithm knows I'm not a fan of the political echo chamber on here (same with Twitter, though), so it's started to flood my feed entirely with BioRxiv preprints...
June 25, 2025 at 5:05 AM
I think the algorithm knows I'm not a fan of the political echo chamber on here (same with Twitter, though), so it's started to flood my feed entirely with BioRxiv preprints...
18 hours later and my AI training status is at 3% done...
At least it's running?
At least it's running?
June 1, 2025 at 3:54 PM
18 hours later and my AI training status is at 3% done...
At least it's running?
At least it's running?
My second preprint, and first sole-author paper. I worked on this idea for several months now, mulling it over and refining it until it came together. Feedback welcome
Ontoenergetics: A Thermodynamic Theory of Life, Aging, and Death
osf.io/preprints/os... via @cos.io
Ontoenergetics: A Thermodynamic Theory of Life, Aging, and Death
osf.io/preprints/os... via @cos.io
OSF
osf.io
May 13, 2025 at 2:00 AM
My second preprint, and first sole-author paper. I worked on this idea for several months now, mulling it over and refining it until it came together. Feedback welcome
Ontoenergetics: A Thermodynamic Theory of Life, Aging, and Death
osf.io/preprints/os... via @cos.io
Ontoenergetics: A Thermodynamic Theory of Life, Aging, and Death
osf.io/preprints/os... via @cos.io
My first ever preprint is out!
This project was an idea that I wasn't sure would work out. Turns out it was pretty fantastic. There's to come, too!
This project was an idea that I wasn't sure would work out. Turns out it was pretty fantastic. There's to come, too!
In our second kidney paper out from our lab this week, Dr. Stephen Decker @decker-st.bsky.social describes a novel and elegant bioenergetic platform to successfully resolve kidney segments with highly differential response to nephropathy.
A Platform for Mitochondrial Profiling in Enriched Kidney Segments Under Thermodynamic Control
Mitochondrial function varies widely across kidney nephron segments, yet conventional approaches lack the resolution and control needed to assess cell-type-specific bioenergetics in situ. We present a...
doi.org
May 10, 2025 at 6:49 AM
My first ever preprint is out!
This project was an idea that I wasn't sure would work out. Turns out it was pretty fantastic. There's to come, too!
This project was an idea that I wasn't sure would work out. Turns out it was pretty fantastic. There's to come, too!
Trying to find my text when I move a figure in Word
a young boy in a blue shirt is looking up at something in the sky .
ALT: a young boy in a blue shirt is looking up at something in the sky .
media.tenor.com
May 9, 2025 at 12:26 AM
Trying to find my text when I move a figure in Word
Awesome study. Wish they would have done something with cardiolipin though
Mitochondrial membrane hyperpolarization modulates nuclear DNA methylation and gene expression through phospholipid remodeling - Nature Communications
The authors show that mitochondria can chronically hyperpolarize under normal or disease conditions and be induced by environmental exposures. This triggers phospholipid remodeling, which in turn affe...
www.nature.com
May 7, 2025 at 3:13 AM
Awesome study. Wish they would have done something with cardiolipin though
Reposted by Stephen Decker, PhD
A new paper from Precious Opurum (PhD candidate) demonstrates for the first time in mice that a sedentary behaviour may contribute to the development of chronic kidney disease.
doi.org/10.1152/ajpr...
doi.org/10.1152/ajpr...
May 6, 2025 at 3:42 PM
A new paper from Precious Opurum (PhD candidate) demonstrates for the first time in mice that a sedentary behaviour may contribute to the development of chronic kidney disease.
doi.org/10.1152/ajpr...
doi.org/10.1152/ajpr...