Indeed: as this sort of scientific exchanges (paper → comment → response) go, this was one of the best I've been involved in. And, again, it makes it clear that sharing the data and code, and being clear about what was done and why (as Bodo, Márton, Marcus & Mark did) are essential for science.

Very interesting! (I won't be there but would be nice to see the poster/paper in some form :))

Beethoven, one of the most celebrated musicians in history, scored unremarkably on the musicality-related polygenic index, ranking between the 9th & 11th percentile based on modern samples. In our paper we explain why this is no surprise & how it offers a nice example for teaching complex genetics.