David Stachura, PhD
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davidstachura.bsky.social
David Stachura, PhD
@davidstachura.bsky.social
28 followers 55 following 68 posts
Scientist, mentor, and father that loves bikes, vintage Italian scooters, and classic Volkswagens. Expert in stem cell biology, immunology, developmental biology, and hematology developing treatments for a multitude of human diseases.
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davidstachura.bsky.social
David Stachura, PhD @davidstachura.bsky.social · Jan 9
You can see all my current research on LinkedIn (www.linkedin.com/in/davidstac...). Connect with me there!
David Stachura - Chico, California, United States | Professional Profile | LinkedIn
Chief Scientific Officer of SpecBio and FACTORFIVE skincare, CEO and founder of Philanthropic Pharma, Inc · I have extensive experience in studying a variety of adult stem cell types in zebrafish, mic...
linkedin.com
Reposted by David Stachura, PhD
cp-cell.bsky.social
Now online! Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy
Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy
MiTEs are myeloid-targeted immunocytokine prodrugs that block TREM2+ tumor-associated macrophages while activating cytotoxic lymphocytes via TME-specific IL-2 activity, eliciting strong anti-tumor efficacy in preclinical models with minimal systemic toxicity.
dlvr.it
November 19, 2025 at 11:38 PM
davidstachura.bsky.social
Awesome video describing @FactorFiveSkin EXOFECTA, our flash-frozen lyophilized exosome product with stem cell proteins and copper peptides. #stemcells #skincare #biotech

www.youtube.com/watch?v=6fuB...
The Story Behind EXOFECTA: How It’s Made, Why It Works, and What Makes It Different
YouTube video by FACTORFIVE Skincare
www.youtube.com
November 19, 2025 at 12:31 AM
davidstachura.bsky.social
“Shared family factors, such as parental mental health, genetic predisposition, and socioenvironmental background, explain much of the observed risk.” IOW: it's not Tylenol causing autism... #autismawareness #tylenol

www.medscape.com/viewarticle/... www.medscape.com/viewarticle/...
No Clear Evidence of Tylenol-Autism Link, Major Review Shows
Family genetics and environment, rather than acetaminophen exposure during pregnancy, may explain earlier reported links to autism, a comprehensive new review shows.
www.medscape.com
November 17, 2025 at 7:16 PM
davidstachura.bsky.social
"...bespoke therapies are close to reality. The FDA will work as a partner and guide in ushering these therapies to market, and our regulatory strategies will evolve to match the pace of scientific advances."

Great info from the @FDA!

www.nejm.org/doi/pdf/10.1...
FDA’s New Plausible Mechanism Pathway | NEJM
Personalized therapies hold tremendous promise but challenge traditional models of drug and biologic development. The FDA outlines a path to market entry for products where a randomized trial is no...
www.nejm.org
November 16, 2025 at 8:05 PM
davidstachura.bsky.social
Here's the white paper you've been waiting for- an independent analysis from @ucdavis.bsky.social scientists showing that flash frozen lyophilized EXOFECTA @FactorFive contains exosomes! #exosomes #stemcells #skincare

medium.com/@davidstachu...
Validation of Extracellular Vesicles in FACTORFIVE’s EXOFECTA LyoBeads
Analysis by an independent laboratory showing that FACTORFIVE’s EXOFECTA lyobeads contain a multitude of extracellular vessicles
medium.com
November 16, 2025 at 7:45 PM
davidstachura.bsky.social
Our @FactorFiveSkin no-downtime chemical peel was featured in @ParadeMagazine as a dermatologist-recommended method of increasing collagen! #skincare #stemcells

parade.com/living/skinc...
parade.com
November 15, 2025 at 5:47 PM
davidstachura.bsky.social
Cool technology that allows accurate non-invasive imaging of skin. Great for dermatologists, but also could be used to show efficacy of skin care products! #skincare #dermatology

jamanetwork.com/journals/jam...
Cross-Modal Imaging in Noninvasive Identification of Histologic Features of Skin
This study evaluates the safety and effectiveness of the cross-modal system in obtaining in vivo images that show tissue features, align with corresponding pathology images from biopsies, and evaluate...
jamanetwork.com
November 13, 2025 at 5:03 PM
davidstachura.bsky.social
Adult meat and shellfish allergies are on the rise. But, why? #immunology #allergies

www.medscape.com/viewarticle/...
Adult-Onset Food Allergies Warrant ‘High Index of Suspicion’
The allergens may be different in adult-onset allergy, but the potentially dangerous reactions are the same as in children.
www.medscape.com
November 12, 2025 at 9:05 PM
davidstachura.bsky.social
Good info about allergies and common misconceptions that surround them... #immunology #allergies

www.medscape.com/viewarticle/...
Many Beliefs About Allergies Unsupported by Evidence
Extreme elimination diets and similar drastic measures can cause unnecessary stress when many allergy issues could benefit from more thoughtful management.
www.medscape.com
November 6, 2025 at 6:44 PM
davidstachura.bsky.social
Exciting development of a blood test to detect pancreatic cancer, which currently has a 5-year survival rate of only 13%. #CancerResearch

acg2025.eventscribe.net/fsPopup.asp?...
ACG 2025 Annual Meeting
acg2025.eventscribe.net
November 5, 2025 at 6:50 PM
davidstachura.bsky.social
Exciting new GLP-1 agonist drugs on the very near horizon... #glp1 #obesity #peptides

www.medscape.com/viewarticle/...
Anti-Obesity Medications Set to Explode Entering 2026
From oral formulations to double and triple agonists, the race is on for the next big thing in obesity drugs.
www.medscape.com
November 4, 2025 at 1:56 AM
davidstachura.bsky.social
I introduced my children to peanuts and tree nuts immediately after they could eat solid foods. Here's evidence that it's a good idea for reducing allergies! #Immunology #allergies @Childrens Hospital of Philadelphia
www.medscape.com/viewarticle/...
Food Allergy Rates Fall After 2015 Peanut Feeding Advice
Peanut allergies in children under 3 have dropped by more than a quarter since 2015 when experts began recommending early peanut introduction, a new study finds.
www.medscape.com
October 29, 2025 at 10:36 PM
davidstachura.bsky.social
Nice write up of @FactorFiveSkin's brand new EXOFECTA lyophilized stem cell derived proteins and exosomes in @MedEstheticsMag #skincare #exosomes #stemcells

medestheticsmag.texterity.com/medesthetics...
MedEsthetics - October 2025 : Page 6
INTRODUCTIONS A recently published study in the journal Aging explores howcomponents in young human blood serum can restore youthfulproperties to skin, but only when bone marrow cells are present...
medestheticsmag.texterity.com
October 21, 2025 at 10:57 PM
davidstachura.bsky.social
Looks like Depo-Provera might cause a rare type of brain cancer. Lawsuits claim that Pfizer knew, but they claim the FDA prevented them from warning consumers. Who's right here? #depoprovera #BigPharma

www.reuters.com/legal/litiga...
www.reuters.com
October 16, 2025 at 4:19 PM
davidstachura.bsky.social
@FactorFiveSkin EXOFECTA lyophilized stem cell growth factors and exosomes featured in @DERMASCOPE #skincare #stemcells

www.dermascope.com/freedigital/...
DERMASCOPE
www.dermascope.com
October 11, 2025 at 6:14 PM
davidstachura.bsky.social
“However, as their prescribing expands, we are seeing more and more unexpected side effects being reported in the literature." Get ready for more side effects as more and more people use GLP-1 agonists to lose weight...

www.medscape.com/viewarticle/...
Telogen Effluvium and Alopecia Rates High in GLP-1 RA Users
Real-world data showed high incidence of hair loss among GLP-1 receptor agonist users, but the phenomenon is probably an unmasking, rather than a direct effect.
www.medscape.com
October 7, 2025 at 5:11 PM
davidstachura.bsky.social
Some research I thought I would share from one of my old student's research projects. Cool stuff about cannabinoids, growing stem cells in 3D cultures, and blood! #immunology

medium.com/p/cannabinoi...
Cannabinoid Receptor 2 (CNR2) Agonist AM1241 Fails to Expand Adult Danio rerio (Zebrafish)…
Francis Wright, Gabriel Marquez, David L Stachura
medium.com
October 3, 2025 at 3:56 PM
davidstachura.bsky.social
Could skincare ingredients trigger the hormone that makes us feel good, while clinically treating the skin simultaneously? Interesting read... #skincare #science #dermatology

www.medestheticsmag.com/home/article...
Oxytocin for the Epidermis: How Psychodermatology Is Turning Aesthetics into Emotional Medicine
XOMD OX Factor is tapping into the brain’s oxytocin chemistry.
www.medestheticsmag.com
October 3, 2025 at 1:55 AM
davidstachura.bsky.social
Amazing results using a virus to deliver microRNA to successfully treat Hungtington's disease! This pushes us into a new era of gene therapy treatments for disease! #immunology #genetherapy #Huntingtonsdisease

bbc.com/news/article...
Huntington's disease successfully treated for first time
One of the most devastating diseases finally has a treatment that can slow its progression and transform lives, tearful doctors tell BBC.
bbc.com
October 1, 2025 at 6:14 PM
davidstachura.bsky.social
Producing ExoFecta LyoBeads filled with copper peptides, growth factors, and exosomes! @FactorFiveSkin #exosomes #science #skincare #stemcells

youtube.com/shorts/Q0sbS...
ExoFecta LyoBeads from FACTORFIVE Skincare being frozen in liquid nitrogen #skincare #exosomes
YouTube video by Dr. David Stachura's Science Video Page
youtube.com
September 30, 2025 at 12:06 AM
davidstachura.bsky.social
Another great podcast on vaccines with commentary from @DrPaulOffit @Penn @ChildrensPhila

Check it out!

www.npr.org/2025/09/25/n...
The Anti-Vaccine Movement : Throughline
The alleged link between vaccines and autism is back in the news this week, being regularly speculated on by both President Trump and Health and Human Services secretary Robert F. Kennedy Jr.  The cla...
www.npr.org
September 29, 2025 at 3:30 PM
davidstachura.bsky.social
American Spa featured our Exofecta novel lyobead exosome, growthfactor, and peptide product as a "new medical spa product(s) to check out!" #skincare @FactorFiveSkin

www.americanspa.com/medical-spa/...
New Medical Spa Products to Check Out
The AuraLux cold fiber laser from Acclaro Medical is designed to prevent and correct the signs of skin aging using advanced engineering that helps to improve skin’s appearance. | Discover the latest p...
www.americanspa.com
September 28, 2025 at 3:55 AM
davidstachura.bsky.social
I don't like the term "cosmeceutical," and neither does the FDA. Regardless, these chemical compounds have lots of research validating their positive effects for #acne, #dematitis, and #melasma. #skincare

www.medscape.com/viewarticle/... www.medscape.com/viewarticle/...
Which Cosmeceuticals Are Backed Up by Research?
Dermatologist highlights cosmeceutical products useful in the management of acne, atopic dermatitis, and melasma.
www.medscape.com
September 26, 2025 at 12:52 AM
davidstachura.bsky.social
This is a must listen- @DrPaulOffit is a wealth of knowledge about vaccines and presents the issues going on so well. #Vaccines @ChildrensPhila @NPR @onthemedia @WNYC

Paul Offit Has Opinions About RFK Jnr. www.wnycstudios.org/story/paul-o... via @onthemedia
Paul Offit Has Opinions About RFK Jnr. | On the Media | WNYC Studios
A vaccine specialist on what the changes RFK Jr has wrought will mean for public health.
www.wnycstudios.org
September 23, 2025 at 1:19 AM
davidstachura.bsky.social
Interesting. However, antioxidants aren't the panacea for stopping senescence of skin cells. Antioxidants are only part of the issue with aging skin. Peptides and growth factors are needed to signal rejuvenation! @FactorFiveSkin #skincare #stemcells

www.medestheticsmag.com/products/art...
Martha Stewart Is Tackling Anti-Aging Skincare? Yes, The Home Decor Icon Enters the Clinical Beauty Space
Martha Stewart Is Tackling Anti-Aging Skincare With Elm Biosciences
www.medestheticsmag.com
September 20, 2025 at 6:09 AM