David Hettle
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david-hettle.bsky.social
David Hettle
@david-hettle.bsky.social
Doctor: Infectious Diseases/Microbiology

Currently @ebibristol.bsky.social + @thruzim.bsky.social Global Health Fellow in 🇿🇼 exploring lab systems: AMR, promoting antimicrobial stewardship, TB.

#MedEd. Interests: career development of MedEd-ucators
Great to join #ReActAfrica and @southcentre.bsky.social at #AARC25 for 2 days of discussion and learning about #AMR across Africa

#antimicrobialresistance
June 11, 2025 at 7:05 AM
Look after patients with neonatal sepsis in sub-Saharan Africa?

🫵We want to hear from YOU!

❓Why❓
Exploring clinicians experiences of diagnostics, antibiotics + guidelines

📢 English, French or Portuguese

🔗 redcap.sun.ac.za/surveys/?s=N9A…
April 22, 2025 at 7:37 PM
Reposted by David Hettle
📢 Healthcare workers across Africa — we want to hear from you! Together, we can improve newborn health in LMICs. 💪👶Don't forget to take our survey before 10 May 2025!📝
🔗 redcap.sun.ac.za/surveys/?s=N...
April 22, 2025 at 1:08 PM
Reposted by David Hettle
Sepsis is one of the most frequent causes of death worldwide & yet in many LMICs we have no or low quality phenotypic diagnostics to guide our therapy. This is particularly problematic in the context of neonatal sepsis where ESBL Kleb pneumo is often implicated. @lshtmamrcentre.bsky.social
April 10, 2025 at 8:54 AM
Back at the #ESCMIDGlobal clinical round - watching the experts' #clinicalreasoning in all kinds of cases

🧫 First up - Whipple's disease

Long-term arthralgia
Cardiac involvement
Persistent diarrhea even after fevers settle

#ESCMID2025 #IDSky
April 15, 2025 at 6:56 AM
Amazing to present our work (with @tinamwat.bsky.social) on developing blood culture processes in Harare 🇿🇼 at #ESCMID2025 #ESCMIDGlobal

And great to meet others + chat about the work's impact in #neonatalsepsis + #AMR #AMS #antimicrobialstewardship

@thruzim.bsky.social
April 14, 2025 at 2:33 PM
Essential diagnostics in low-resource settings

Sipho Dlamini, Dissou Affolabi, @makedasemret.bsky.social insights on
💥 Brain drain
💥 Lack of granularity in calls to improve
💡 Lessons of networks (echoing TB labs) in SSA

Current status: www.thelancet.com/journals/lan...

#ESCMIDGlobal #ESCMID2025
April 13, 2025 at 12:15 PM
#AI is here + will become key in #antimicrobialstewardship #AMS

Flagged by Prof Thursky @ncas.bsky.social at #ESCMID2025 #ESCMIDGlobal - this paper is a great blueprint for implementing AI in AMS programmes

Link: www.thelancet.com/journals/lan...
April 13, 2025 at 9:48 AM
New Frontiers in Antimicrobial Stewardship @escmid.bsky.social

Keynote lecture: Karin Thursky @ncas.bsky.social

How can we reframe + conceptualize #AMS to work for 2025 + beyond.

Who outside of healthcare really know the ins and outs of what #AMR #AMS mean?

#ESCMIDGlobal #ESCMID2025
April 13, 2025 at 9:16 AM
Critical talk to think about moving from #AMR surveillance + antibiotic use data
⬇️
Stewardship initiatives #AMS

Talk from Mark de Boer on bridging the gap!

#ESCMIDglobal #ESCMID2025
April 13, 2025 at 7:46 AM
Starting Sunday at #ESCMID2025 #ESCMIDglobal debating 'Proxy indicators: bridging the gap between #AMR surveillance and #antimicrobialstewardship #AMS

Finding a way to tie quantity metrics to appropriateness of prescription

A start to #AMS Sunday according to @dianeashiru.bsky.social
April 13, 2025 at 6:54 AM
Are you at #ESCMID2025 #ESCMIDglobal?

Do you care for patients with neonatal sepsis, and work in sub-Saharan Africa?

Please complete this survey looking at care of neonates + fighting #AMR in sub-Saharan Africa

#neonates #neonatalsepsis #sepsis
Do you care for patients with neonatal sepsis in sub-Saharan Africa?

🫵We want to hear from YOU!

redcap.sun.ac.za/surveys/?s=N9A…

❓Why❓
To explore clinicians views on diagnostics, antibiotics and guidelines

📢In English, French or Portuguese.#neonatalsepsisi#neonatese#sepsisis
April 12, 2025 at 2:25 PM
April 12, 2025 at 1:40 PM
Reposted by David Hettle
Molecular cartridge based diagnostics have been a game changer for TB diagnostics - why can we not do the same for blood cultures?
Please see our newest publication in collaboration with FIND, Sally Mugabe Central Hospital, the NMRL & @thruzim.bsky.social

PLOS: dx.plos.org/10.1371/jour...
Rapid bacterial identification and resistance detection using a low complexity molecular diagnostic platform in Zimbabwe
Background Sepsis is a major cause of mortality in low-resource settings. Effective microbiological culture services are a bottleneck in diagnosis and surveillance. Aim We aimed to evaluate the perf...
dx.plos.org
April 10, 2025 at 8:03 AM
Do you care for patients with neonatal sepsis in sub-Saharan Africa?

🫵We want to hear from YOU!

redcap.sun.ac.za/surveys/?s=N9A…

❓Why❓
To explore clinicians views on diagnostics, antibiotics and guidelines

📢In English, French or Portuguese.#neonatalsepsisi#neonatese#sepsisis
April 12, 2025 at 1:16 PM