Daniel M Spagnolo
@daniel-m-spagnolo.bsky.social
Computational Biologist / Bioinformatician working on novel cancer therapies. Knowledgeable in genomics, multi-omics, bioimaging, and tumour heterogeneity. Pitt-CMU CPCB alumnus. American scientist working (and cycling!) across Cambridge, UK.
Excellent @fogenomics.bsky.social session on AI in drug discovery chaired by @tomdiethe.com w/ an extremely succinct explanation of different generative models & the utility of synthetic data from Helena Andres Terre & a vision for disrupting the drug discovery paradigm/timeline from Sergei Yakneen
January 30, 2025 at 6:23 PM
Excellent @fogenomics.bsky.social session on AI in drug discovery chaired by @tomdiethe.com w/ an extremely succinct explanation of different generative models & the utility of synthetic data from Helena Andres Terre & a vision for disrupting the drug discovery paradigm/timeline from Sergei Yakneen
One of my favorite talks of the day at @fogenomics.bsky.social was Brendan Frey from Deep Genomics discussing the advantages of foundation models with the use case of predicting RNA regulatory mechanisms and designing RNA therapeutics. More details at: www.biorxiv.org/content/10.1...
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics
Accurately modeling and predicting RNA biology has been a long-standing challenge, bearing significant clinical ramifications for variant interpretation and the formulation of tailored therapeutics. W...
www.biorxiv.org
January 29, 2025 at 8:49 PM
One of my favorite talks of the day at @fogenomics.bsky.social was Brendan Frey from Deep Genomics discussing the advantages of foundation models with the use case of predicting RNA regulatory mechanisms and designing RNA therapeutics. More details at: www.biorxiv.org/content/10.1...
ExCeL London / @fogenomics.bsky.social catering to its captive audience of nerds with an X-Wing Starfighter on display #starwars #rebelalliance
January 29, 2025 at 1:28 PM
ExCeL London / @fogenomics.bsky.social catering to its captive audience of nerds with an X-Wing Starfighter on display #starwars #rebelalliance
Great talk at Festival of Genomics this morning from @adamrutherford.bsky.social on scientific racism & the eugenic origins of the field of genetics. One takeaway: “standard genetics teaching increases racist essentialist thinking” in students, instead we should start by introducing complex traits.
January 29, 2025 at 12:34 PM
Great talk at Festival of Genomics this morning from @adamrutherford.bsky.social on scientific racism & the eugenic origins of the field of genetics. One takeaway: “standard genetics teaching increases racist essentialist thinking” in students, instead we should start by introducing complex traits.
Excited to attend the Festival of Genomics, which also bookmarks my 1 year milestone at Artios! Looking forward to hearing from the diverse roster of speakers, and making some professional connections.
Hear from these speakers in less than a week at #FOG2025!
Expect 360+ experts, sharing their knowledge across topics covering genomic medicine, biodata, liquid biopsy, proteomics, sequencing, women's health, cancer omics & much more!
hubs.ly/Q02-RWvR0
#genomics #biodata #lifescience
Expect 360+ experts, sharing their knowledge across topics covering genomic medicine, biodata, liquid biopsy, proteomics, sequencing, women's health, cancer omics & much more!
hubs.ly/Q02-RWvR0
#genomics #biodata #lifescience
January 27, 2025 at 1:53 PM
Excited to attend the Festival of Genomics, which also bookmarks my 1 year milestone at Artios! Looking forward to hearing from the diverse roster of speakers, and making some professional connections.