Cardiovascular Innovations and Applications
@cvia-journal.org
Platinum open-access journal in cardiovascular medicine.
Impact Factor 1.4 | CiteScore 1.2 | SJR Q3.
Publishing innovative research with rapid peer review & no author fees.
https://cvia-journal.org
Impact Factor 1.4 | CiteScore 1.2 | SJR Q3.
Publishing innovative research with rapid peer review & no author fees.
https://cvia-journal.org
Pinned
CVIA is proud to announce that the journal's #CiteScore has increased to 1.2 this year!
This demonstrates the growing impact our journal has in #cardiovascular research.
We thank our authors, reviewers, and editorial board.
#OpenAccess: cvia-journal.org
#Cardiology #Scicomm #medsky
This demonstrates the growing impact our journal has in #cardiovascular research.
We thank our authors, reviewers, and editorial board.
#OpenAccess: cvia-journal.org
#Cardiology #Scicomm #medsky
This editorial discusses extracellular vesicle‑miRNAs as early biomarkers and therapeutic targets, redefining precision care in acute myocardial infarction. @harvardmed.bsky.social
#OpenAccess: cvia-journal.org/extracellula...
#OpenAccess: cvia-journal.org/extracellula...
Extracellular Vesicle-Derived miRNA in Acute Myocardial Infarction
This editorial discusses extracellular vesicle‑miRNAs as early biomarkers and therapeutic targets, redefining precision care in acute myocardial infarction.
cvia-journal.org
November 11, 2025 at 6:53 AM
This editorial discusses extracellular vesicle‑miRNAs as early biomarkers and therapeutic targets, redefining precision care in acute myocardial infarction. @harvardmed.bsky.social
#OpenAccess: cvia-journal.org/extracellula...
#OpenAccess: cvia-journal.org/extracellula...
This research letter integrates #MultiOmics & #MendelianRandomization analyses to identify #PANoptosis genes #BCL2L1 and UBC as key regulators of #MyocardialInfarction (MI) via #DNAMethylation, revealing BCL2L1 as a promising therapeutic target for MI intervention.
#OpenAccess: tinyurl.com/2yxas89v
#OpenAccess: tinyurl.com/2yxas89v
Potential Therapeutic Targets of PANoptosis for Myocardial Infarction: A Summary-Data-Based Mendelian Randomization Study Integrating eQTL, mQTL, and Multi-GWAS Data
This study explores PANoptosis as a therapeutic target for myocardial infarction using Mendelian randomization and multi-omics data analysis.
tinyurl.com
November 6, 2025 at 12:32 PM
This research letter integrates #MultiOmics & #MendelianRandomization analyses to identify #PANoptosis genes #BCL2L1 and UBC as key regulators of #MyocardialInfarction (MI) via #DNAMethylation, revealing BCL2L1 as a promising therapeutic target for MI intervention.
#OpenAccess: tinyurl.com/2yxas89v
#OpenAccess: tinyurl.com/2yxas89v
Reposted by Cardiovascular Innovations and Applications
📈A study of 96 patients using a new biodegradable #PFO closure device shows no deaths, no device-related embolism/thrombus/erosion, and full degradation of the device by year two.
Learn more with this Cardiovascular Business article ➡️ https://ow.ly/yhbL50XjZAP
#CardioSky
Learn more with this Cardiovascular Business article ➡️ https://ow.ly/yhbL50XjZAP
#CardioSky
New biodegradable PFO closure device shows early potential
Researchers tracked patients for two years, using echocardiography to confirm the devices had completely vanished. Additional studies will still be required.
ow.ly
November 1, 2025 at 3:00 PM
📈A study of 96 patients using a new biodegradable #PFO closure device shows no deaths, no device-related embolism/thrombus/erosion, and full degradation of the device by year two.
Learn more with this Cardiovascular Business article ➡️ https://ow.ly/yhbL50XjZAP
#CardioSky
Learn more with this Cardiovascular Business article ➡️ https://ow.ly/yhbL50XjZAP
#CardioSky
Reposted by Cardiovascular Innovations and Applications
Interested in being a mentor? The ACC is seeking volunteer mentors for its #ACCIMProgram ➕ Pediatric Residents Cardiology Programs. Get involved and inspire the next generation of #cardiology professionals.
Learn more and apply by Dec. 10 👉 https://bit.ly/472nhdW #ACCHealthEquity #cvPed
Learn more and apply by Dec. 10 👉 https://bit.ly/472nhdW #ACCHealthEquity #cvPed
November 1, 2025 at 8:53 PM
Interested in being a mentor? The ACC is seeking volunteer mentors for its #ACCIMProgram ➕ Pediatric Residents Cardiology Programs. Get involved and inspire the next generation of #cardiology professionals.
Learn more and apply by Dec. 10 👉 https://bit.ly/472nhdW #ACCHealthEquity #cvPed
Learn more and apply by Dec. 10 👉 https://bit.ly/472nhdW #ACCHealthEquity #cvPed
Reposted by Cardiovascular Innovations and Applications
Supporters of transcatheter tricuspid valve interventions for severe TR are reassured by new real-world and extended trial data, presented at this year's #TCT2025. But longer-term follow up is still needed to answer continued questions on safety and efficacy. www.tctmd.com/news/more-da...
More Data on Tricuspid Valve Interventions Reassure, yet Questions Remain
The real-world Evoque and new TRILUMINATE findings provide an “extension” from the pivotal trials, Dharam Kumbhani says.
www.tctmd.com
November 2, 2025 at 2:21 PM
Supporters of transcatheter tricuspid valve interventions for severe TR are reassured by new real-world and extended trial data, presented at this year's #TCT2025. But longer-term follow up is still needed to answer continued questions on safety and efficacy. www.tctmd.com/news/more-da...
Reposted by Cardiovascular Innovations and Applications
📢 Join the November JCMR Journal Club Webinar!
Explore how heart shape & function relate to disease — insights from 38,858 UK Biobank participants.
🗓️ Nov 12, 2025 | 11:00 am–12:00 pm ET
🔗Register now : bit.ly/4oJRfZT
Explore how heart shape & function relate to disease — insights from 38,858 UK Biobank participants.
🗓️ Nov 12, 2025 | 11:00 am–12:00 pm ET
🔗Register now : bit.ly/4oJRfZT
October 30, 2025 at 3:07 PM
📢 Join the November JCMR Journal Club Webinar!
Explore how heart shape & function relate to disease — insights from 38,858 UK Biobank participants.
🗓️ Nov 12, 2025 | 11:00 am–12:00 pm ET
🔗Register now : bit.ly/4oJRfZT
Explore how heart shape & function relate to disease — insights from 38,858 UK Biobank participants.
🗓️ Nov 12, 2025 | 11:00 am–12:00 pm ET
🔗Register now : bit.ly/4oJRfZT
Reposted by Cardiovascular Innovations and Applications
📢 #ISC26 CFA submission deadline extended
Your research deserves the spotlight—submit your International Stroke Conference abstract by Oct. 30 at 11:59 p.m. ET.
Don’t miss your chance to share your science on the world stage.
Your research deserves the spotlight—submit your International Stroke Conference abstract by Oct. 30 at 11:59 p.m. ET.
Don’t miss your chance to share your science on the world stage.
October 30, 2025 at 3:44 PM
📢 #ISC26 CFA submission deadline extended
Your research deserves the spotlight—submit your International Stroke Conference abstract by Oct. 30 at 11:59 p.m. ET.
Don’t miss your chance to share your science on the world stage.
Your research deserves the spotlight—submit your International Stroke Conference abstract by Oct. 30 at 11:59 p.m. ET.
Don’t miss your chance to share your science on the world stage.
Reposted by Cardiovascular Innovations and Applications
#ACVC26 abstract submission deadline extended, giving you more time to share your work & shape practice in acute care
Bring your science to a community built on teamwork, learning, & action
Deadlines: Abstracts: 4 Nov | Clinical cases: 6 Nov https://bit.ly/4hJQzBh
#ACVC_ESC
Bring your science to a community built on teamwork, learning, & action
Deadlines: Abstracts: 4 Nov | Clinical cases: 6 Nov https://bit.ly/4hJQzBh
#ACVC_ESC
October 30, 2025 at 2:02 PM
#ACVC26 abstract submission deadline extended, giving you more time to share your work & shape practice in acute care
Bring your science to a community built on teamwork, learning, & action
Deadlines: Abstracts: 4 Nov | Clinical cases: 6 Nov https://bit.ly/4hJQzBh
#ACVC_ESC
Bring your science to a community built on teamwork, learning, & action
Deadlines: Abstracts: 4 Nov | Clinical cases: 6 Nov https://bit.ly/4hJQzBh
#ACVC_ESC
Reposted by Cardiovascular Innovations and Applications
The need for a cardiac implantable electronic device (CIED) before or after undergoing TTVR does not have a significant impact on all-cause death or hospitalization for HF at 1 year, according to an analysis of TRISCEND and TRISCEND II. #TCT2025 www.tctmd.com/news/ttvr-re...
TTVR Remains Safe, Effective in Presence of CIED Leads
The rate of death or HF hospitalization was not influenced by the presence of leads after accounting for comorbidity burden.
www.tctmd.com
October 30, 2025 at 2:03 PM
The need for a cardiac implantable electronic device (CIED) before or after undergoing TTVR does not have a significant impact on all-cause death or hospitalization for HF at 1 year, according to an analysis of TRISCEND and TRISCEND II. #TCT2025 www.tctmd.com/news/ttvr-re...
This #CVIA review provides an overview of the #Epidemiology & #Pathology of #DiabeticCardiomyopathy (DCM) with insights into the complex interactions between #miRNAs & immune pathways in DCM, highlighting the potential of miRNA-based interventions in DCM management. #OpenAccess: tinyurl.com/2c9gy4dw
MicroRNAs Have an Immunomodulatory Role in Diabetes Mellitus and Diabetic Cardiomyopathy
miRNAs play a key role in immune regulation in diabetic cardiomyopathy, offering potential therapeutic targets for improved treatment strategies.
tinyurl.com
October 30, 2025 at 5:47 PM
This #CVIA review provides an overview of the #Epidemiology & #Pathology of #DiabeticCardiomyopathy (DCM) with insights into the complex interactions between #miRNAs & immune pathways in DCM, highlighting the potential of miRNA-based interventions in DCM management. #OpenAccess: tinyurl.com/2c9gy4dw
This study shows #MachineLearning models to estimate peak VO₂ using non-exercise clinical data in #HeartTransplant candidates, achieving predictive accuracy & highlighting key predictors like TAPSE/PASP, proBNP, & #hemoglobin practical #CPET alternative.
#OpenAccess: cvia-journal.org/ml-model-pea...
#OpenAccess: cvia-journal.org/ml-model-pea...
A Machine Learning Approach to Non-Exercise Prediction of Peak VO 2 in Advanced Heart Failure
ML models using non-exercise clinical data can estimate peak VO₂ in heart transplant candidates, aiding evaluation when CPET is not feasible.
cvia-journal.org
October 24, 2025 at 1:14 PM
This study shows #MachineLearning models to estimate peak VO₂ using non-exercise clinical data in #HeartTransplant candidates, achieving predictive accuracy & highlighting key predictors like TAPSE/PASP, proBNP, & #hemoglobin practical #CPET alternative.
#OpenAccess: cvia-journal.org/ml-model-pea...
#OpenAccess: cvia-journal.org/ml-model-pea...
A commentary discussing the use of #CatheterAblation as first-line therapy for selected patients with #AtrialFibrillation and #HeartFailure, covering current guidelines, limitations, and future perspectives. #CVIA
#OpenAccess: tinyurl.com/28a6la8o
#OpenAccess: tinyurl.com/28a6la8o
Catheter Ablation as the First-Line Therapy for Atrial Fibrillation: Update on Evidence and Clinical Implications
Advancements in atrial fibrillation therapy highlight catheter ablation as a key treatment, especially for select patients and those with heart failure.
tinyurl.com
October 23, 2025 at 11:15 AM
A commentary discussing the use of #CatheterAblation as first-line therapy for selected patients with #AtrialFibrillation and #HeartFailure, covering current guidelines, limitations, and future perspectives. #CVIA
#OpenAccess: tinyurl.com/28a6la8o
#OpenAccess: tinyurl.com/28a6la8o
This study shows that #OpioidSparingAnesthesia (OSA) using #ultrasound‑guided #NerveBlocks improved QoR‑15 recovery scores, reduced pain, shortened #ventilation time, & decreased hospital stay after #CardiacSurgery, supporting OSA as an effective analgesic approach.
#OpenAccess: tinyurl.com/26hrxyqa
#OpenAccess: tinyurl.com/26hrxyqa
Opioid-Sparing Anesthesia Improves Recovery After Cardiac Surgery
A study finds opioid-sparing anesthesia enhances early recovery, QoR-15 scores, and reduces ventilation time post-cardiac surgery.
tinyurl.com
October 16, 2025 at 10:37 AM
This study shows that #OpioidSparingAnesthesia (OSA) using #ultrasound‑guided #NerveBlocks improved QoR‑15 recovery scores, reduced pain, shortened #ventilation time, & decreased hospital stay after #CardiacSurgery, supporting OSA as an effective analgesic approach.
#OpenAccess: tinyurl.com/26hrxyqa
#OpenAccess: tinyurl.com/26hrxyqa
This study reviews #RadiationInducedCardiomyopathy, outlining its mechanisms, clinical impact & prevention strategies & highlights how modern #RadiationTechniques & cardioprotective interventions enhance early detection & reduce #CardiacToxicity in #CancerSurvivors.
#OpenAccess: tinyurl.com/28nhsbck
#OpenAccess: tinyurl.com/28nhsbck
Strategies to Address Radiation-Induced Restrictive Cardiomyopathy
Explore Radiation-Induced Restrictive Cardiomyopathy: Advances in radiation therapy (3D-CRT, IMRT), DIBH, and protective medications (statins/ACEi) reduce cardiac risk.
tinyurl.com
October 9, 2025 at 3:37 PM
This study reviews #RadiationInducedCardiomyopathy, outlining its mechanisms, clinical impact & prevention strategies & highlights how modern #RadiationTechniques & cardioprotective interventions enhance early detection & reduce #CardiacToxicity in #CancerSurvivors.
#OpenAccess: tinyurl.com/28nhsbck
#OpenAccess: tinyurl.com/28nhsbck
This #CVIA study emphasizes the necessity and benefits of integrating #CardiacRehabilitation along with structured monitoring and detailed assessment in long-term management of advanced #HeartFailure (HF) patients.
Read the #OpenAccess: tinyurl.com/23dhpjdt
Read the #OpenAccess: tinyurl.com/23dhpjdt
Cardiac Rehabilitation in Patients with Advanced Heart Failure
Cardiac Rehabilitation plays a crucial role in managing advanced heart failure, improving patient outcomes through multidisciplinary, long-term care strategies.
tinyurl.com
October 6, 2025 at 2:03 PM
This #CVIA study emphasizes the necessity and benefits of integrating #CardiacRehabilitation along with structured monitoring and detailed assessment in long-term management of advanced #HeartFailure (HF) patients.
Read the #OpenAccess: tinyurl.com/23dhpjdt
Read the #OpenAccess: tinyurl.com/23dhpjdt
This study shows that percutaneous mechanical #Thrombectomy with the Tendvia system was associated with a significantly lower RV/LV diameter ratio, thus highlighting its safety and efficacy in patients with intermediate-risk acute #PulmonaryEmbolism (PE).
#OpenAccess: tinyurl.com/2b9cruuw
#OpenAccess: tinyurl.com/2b9cruuw
Mechanical Thrombectomy System for the Treatment of Intermediate-Risk Acute Pulmonary Embolism: The CLEAR Study
Study shows Treatment of Intermediate-Risk Acute pulmonary embolism safely and effectively reduces RV/LV ratio and PAP, with low bleeding risk and short hospitalization!
tinyurl.com
September 25, 2025 at 11:14 AM
This study shows that percutaneous mechanical #Thrombectomy with the Tendvia system was associated with a significantly lower RV/LV diameter ratio, thus highlighting its safety and efficacy in patients with intermediate-risk acute #PulmonaryEmbolism (PE).
#OpenAccess: tinyurl.com/2b9cruuw
#OpenAccess: tinyurl.com/2b9cruuw
This comprehensive study integrates multi-dataset #bioinformatics, #immune infiltration profiling & functional validation to reveal S100A12 & #BCL6 as key immune-related #biomarkers & #TherapeuticTargets for early #MyocardialInfarction (MI) detection & intervention.
#OpenAccess: tinyurl.com/ymzxo6sm
#OpenAccess: tinyurl.com/ymzxo6sm
Comprehensive Bioinformatics Method to Explore Immune-Related Genes in the Pathogenesis of Myocardial Infarction
Comprehensive bioinformatics reveals Immune-related genes changes in myocardial infarction, identifying promising diagnostic and therapeutic targets.
tinyurl.com
September 18, 2025 at 1:09 PM
This comprehensive study integrates multi-dataset #bioinformatics, #immune infiltration profiling & functional validation to reveal S100A12 & #BCL6 as key immune-related #biomarkers & #TherapeuticTargets for early #MyocardialInfarction (MI) detection & intervention.
#OpenAccess: tinyurl.com/ymzxo6sm
#OpenAccess: tinyurl.com/ymzxo6sm
This study provides quantitative insights into the status of GDMT delivery in hospitalized heart failure patients with malnutrition which suggests integrating nutritional assessment into discharge planning to support effective treatment optimization.
#Openaccess: cvia-journal.org/malnutrition...
#Openaccess: cvia-journal.org/malnutrition...
Management of Malnutrition in Heart Failure to Optimize Guideline-Directed Medical Therapy
This study provides quantitative insights into the status of guideline-directed medical therapy (GDMT) delivery in heart failure patients with malnutrition.
cvia-journal.org
September 15, 2025 at 10:57 AM
This study provides quantitative insights into the status of GDMT delivery in hospitalized heart failure patients with malnutrition which suggests integrating nutritional assessment into discharge planning to support effective treatment optimization.
#Openaccess: cvia-journal.org/malnutrition...
#Openaccess: cvia-journal.org/malnutrition...
This study demonstrates that a novel multi-channel vascular interventional robotic system is safe and effective for #CoronaryAngiography and #stent implantation in animal models, while significantly reducing operator #radiationexposure.
#Openaccess: cvia-journal.org/vascular-int...
#Openaccess: cvia-journal.org/vascular-int...
Efficacy and Safety of a Novel Multi-Channel Vascular Interventional Robotic System: Animal Studies
This study shows a novel robotic PCI system is safe and effective in animal models, achieving high success and reducing operator radiation exposure.
cvia-journal.org
September 15, 2025 at 8:54 AM
This study demonstrates that a novel multi-channel vascular interventional robotic system is safe and effective for #CoronaryAngiography and #stent implantation in animal models, while significantly reducing operator #radiationexposure.
#Openaccess: cvia-journal.org/vascular-int...
#Openaccess: cvia-journal.org/vascular-int...
Explore how #RNAsplicing Cardiac Diseases are linked, reshaping gene expression and driving innovative therapies in modern medicine to save lives. @harvardmed.bsky.social
#Openaccess: tinyurl.com/22faf2ut
#Openaccess: tinyurl.com/22faf2ut
Alternative RNA Splicing in Cardiac Diseases
Explore how RNA Alternative splicing Cardiac Diseases are linked, reshaping gene expression and driving innovative therapies in modern medicine to save lives.
tinyurl.com
September 15, 2025 at 5:03 AM
Explore how #RNAsplicing Cardiac Diseases are linked, reshaping gene expression and driving innovative therapies in modern medicine to save lives. @harvardmed.bsky.social
#Openaccess: tinyurl.com/22faf2ut
#Openaccess: tinyurl.com/22faf2ut
This editorial discusses how integrating #biomarkers with #MachineLearning–based models, such as Apo-CIII, IL-6, & vWF, could enhance timely diagnosis of #Transientischemicattacks, reduce subsequent #stroke burden and improve patient outcomes #CerebrovascularDisease
#OpenAccess: tinyurl.com/299tj4zf
#OpenAccess: tinyurl.com/299tj4zf
Enhancing the Diagnosis of Transient Ischemic Attacks Through Biomarker Innovation
Explore novel biomarkers and AI-driven models enhancing Transient Ischemic Attacks Diagnosis, improving early detection, risk stratification, and timely stroke prevention.
tinyurl.com
September 4, 2025 at 1:43 PM
This editorial discusses how integrating #biomarkers with #MachineLearning–based models, such as Apo-CIII, IL-6, & vWF, could enhance timely diagnosis of #Transientischemicattacks, reduce subsequent #stroke burden and improve patient outcomes #CerebrovascularDisease
#OpenAccess: tinyurl.com/299tj4zf
#OpenAccess: tinyurl.com/299tj4zf
This review outlines strategies to enhance mitochondrial function, such as regulating biogenesis, promoting #mitophagy, using antioxidants, modulating the calcium balance, & optimizing #LipidMetabolism, providing new insights for #DiabeticCardiomyopathy treatment.
#OpenAccess: tinyurl.com/29a62mqs
#OpenAccess: tinyurl.com/29a62mqs
Mitochondrial Dysfunction as a Therapeutic Target in Diabetic Cardiomyopathy: Progress and Prospects
This review highlights new targets and drugs to address mitochondrial dysfunction in diabetic cardiomyopathy (DCM) and slow its progression.
tinyurl.com
August 28, 2025 at 10:49 AM
This review outlines strategies to enhance mitochondrial function, such as regulating biogenesis, promoting #mitophagy, using antioxidants, modulating the calcium balance, & optimizing #LipidMetabolism, providing new insights for #DiabeticCardiomyopathy treatment.
#OpenAccess: tinyurl.com/29a62mqs
#OpenAccess: tinyurl.com/29a62mqs
This case report highlights the successful total endoscopic transcatheter mitral valve-in-valve replacement using a JValve system, combined with leftatrialappendage occlusion & tricuspidrepair, offering a safer alternative to redo #sternotomy with improved outcomes.
cvia-journal.org/total-endosc...
cvia-journal.org/total-endosc...
Total Endoscopic Transcatheter Mitral Valve-in-Valve Replacement with Concomitant Left Atrial Appendage Occlusion and Tricuspid Valve Repair
A case report on the use of a total endoscopic approach for TMVIV replacement with a J-valve system, combined with LAA occlusion and tricuspid valve repair.
cvia-journal.org
August 26, 2025 at 2:58 PM
This case report highlights the successful total endoscopic transcatheter mitral valve-in-valve replacement using a JValve system, combined with leftatrialappendage occlusion & tricuspidrepair, offering a safer alternative to redo #sternotomy with improved outcomes.
cvia-journal.org/total-endosc...
cvia-journal.org/total-endosc...
A geometric multiscale model coupling a 0D-lumped-parameter circulatory system model with a 3D-coronary artery model identified #WallShearStress as a critical hemodynamic indicator for evaluating enhanced external counterpulsation effectiveness.
#OpenAccess: cvia-journal.org/geometric-sc...
#OpenAccess: cvia-journal.org/geometric-sc...
Hemodynamic Evaluation of an Enhanced External Counterpulsation Strategy for Coronary Heart Disease with a Geometric Multiscale Model
Geometric multiscale model provides mechanistic insights into the hemodynamic regulation during enhanced external counterpulsation (EECP) Coronary heart disease.
cvia-journal.org
August 26, 2025 at 2:20 PM
A geometric multiscale model coupling a 0D-lumped-parameter circulatory system model with a 3D-coronary artery model identified #WallShearStress as a critical hemodynamic indicator for evaluating enhanced external counterpulsation effectiveness.
#OpenAccess: cvia-journal.org/geometric-sc...
#OpenAccess: cvia-journal.org/geometric-sc...
This study shows that blood #biomarkers ApoC-III, IL-6 & vWF, combined with clinical data via PanelomiX, can enhance accuracy in distinguishing #TransientIschemicAttacks (TIAs) from mimics, achieving 100% sensitivity in diagnosis.
#OpenAccess: tinyurl.com/26jpupvv
#OpenAccess: tinyurl.com/26jpupvv
A Panel of Blood Biomarkers for the Diagnosis of Transient Ischemic Attacks
This study identifies blood biomarkers (ApoC-III, IL-6, vWF) to improve diagnosis of transient ischemic attacks (TIAs) versus mimics.
tinyurl.com
August 21, 2025 at 2:32 PM
This study shows that blood #biomarkers ApoC-III, IL-6 & vWF, combined with clinical data via PanelomiX, can enhance accuracy in distinguishing #TransientIschemicAttacks (TIAs) from mimics, achieving 100% sensitivity in diagnosis.
#OpenAccess: tinyurl.com/26jpupvv
#OpenAccess: tinyurl.com/26jpupvv