📢 Join us Thursday, November 20th, for a seminar by Dr. Anton Peng titled “Investigating mechanisms of sensory hair cell mechanotransduction.”🧠

🕤 9:30 AM

📅 Thursday, Nov 20

📍 RC1 North, Room 7108

📌 Eligibility:
Professional Research Assistants or staff in comparable roles are eligible.

📝 How to Apply:
Nominate a colleague, advisor, or even yourself!
Submit a nomination letter, job history, and 1–3 reference letters to:
📧 Fadul.Award@ucdenver.edu

🔗 tinyurl.com/fadul-awards

🎉 Exciting News!
Nominations for the 2025 Steven Fadul Award are now open!
Know a standout PRA or staff member at CU School of Medicine? Nominate them today!

Clinically, the findings emphasize the importance of detecting and treating even temporary pediatric hearing loss to prevent enduring effects on spatial hearing and long-term speech and language development.

🎉 Congrats to Daniel Tollin and Nathaniel Greene on yet another achievement! 👏🥳

These deficits persist even after the hearing loss resolves. The research found that deprivation in infancy or childhood—unlike adult-onset loss—produced significant brainstem and behavioral changes, identifying a critical period for developing binaural hearing circuitry.

📢 New PLOS publication from our department! 🧠👂

The study reveals that even brief early-life hearing deprivation, common during childhood ear infections, can cause lasting brainstem processing deficits that impair spatial hearing essential for understanding speech in noisy settings.

🧩 This discovery overturns the long-held assumption that inhibitory neurons act as simple relays, showing instead that their dendrites perform specialized computations that sculpt the timing and flow of cortical activity. 🧠🔬

⚡ Fast-spiking parvalbumin (PV) cells integrate inputs sublinearly, limiting their response and enabling rapid, precisely timed inhibition.

🌊 In contrast, somatostatin (SST) cells integrate supralinearly through NMDA receptors, amplifying inputs to produce slower, more sustained inhibition.

Until now, it was unclear how different inhibitory neurons in the neocortex combine their many inputs to shape brain activity. This study reveals that each interneuron type can have its own distinct dendritic computation.

Exciting News!🧬📖

"Distinct dendritic integration strategies control dynamics of inhibition in the neocortex” authored by Drs. David DiGregorio and Laurance Cathala published on Neuron!

🔗 pubmed.ncbi.nlm.nih.gov/40592329/

@ddigregorio.bsky.social

🧠🔬 Dr. Dan Tollin and Dr. Achim Klug just received a notice of award for a new multi-PI grant from NIH NIDCD which will investigate neural mechanisms involved in hearing in noise such as crowded restaurants! 🍽️ 1/3

🎓 Another academic year, another seminar series by Physiology!

📢 The 2025–2026 Physiology Seminar Series kicks off on August 7th and runs the 1st and 3rd Thursdays of the month through May 21st! 🧠📅

"CU" there!

👏 Dr. Ben-Zheng Li from the Klug lab received the competitive renewal for year 2 of his Emerging Research Grant awarded by the Hearing Health Foundation!🧠🔊 He is studying neural mechanisms of sound localization with a combined approach of physiology and neuronal modeling!

🧠📢 June publications are in!

We’re thrilled to share “Cerebellar circuit computations for predictive motor control” from our very own Person Lab, authored by Abby Person and Katrina P. Nguyen! 📝✨

👉 Click the link in our bio to dive into this exciting research!

What’s more American than fireworks?

Your nervous system reacting to them! 🇺🇸🎇
Happy Independence Day from Physiology & Biophysics! 🧠💥

Dr. Abby Person’s latest review article, “Cerebellar Circuit Computations for Predictive Motor Control,” is now published! It offers valuable insights into how the cerebellum enables prediction and precision in motor control. ➡️ bit.ly/45ymBMG�’s latest review article, “Cerebellar Circuit Computations for Predictive Motor Control,” is now published! It offers valuable insights into how the cerebellum enables prediction and precision in motor control. ➡️ bit.ly/45ymBMG🔗

☀️Fun Physiology Fact for the Summer Solstice!☀️
Your body’s circadian rhythm—your internal clock—is synced to daylight. On the longest day of the year, light-sensitive proteins in your eyes help regulate sleep, hormones & more. That’s biophysics in action! 🌞🧠⏰

📢 We’re thrilled to announce the upcoming release of *Neuroscience and Society* 🧠📘—edited by our very own Gideon Felson, PhD, and Sukumar Vijayaraghavan, PhD, from the Department of Physiology and Biophysics at CU Anschutz Medical Campus! 🎓

Mark your calendar for the release this September!

Today we’re celebrating Selin Schamiloglu (DiGregorio Lab) for receiving an NINDS F32 Grant for: “A cerebellar synaptic mechanism for temporally precise behaviors.”
A huge achievement—congrats, Selin! 🧠🎉

Night Horse Campbell Native Health Building auditorium in action 💪

We had an amazing time at the 25th Annual A.R. Martin Lectureship last week! 🎉 Hosted by Phys on May 14–15, the event featured a keynote by Dr. Marla Feller (@mfeller.bsky.social) and stellar talks from our own trainees—Ana Buteau, Jordan Hickman, and Sujin Jun. 👏

Get ready for this year’s A.R. Martin Lectureship!
Join us on Thursday, May 15 at 9:20AM as Dr. Marla Feller presents “Riding the Retinal Wave through Visual System Development.”

📍 Night Horse Campbell Native Health Building

See you there!

🧠 TED for your Head returns May 8! CU Neurosurgery leads a discussion on Stuff Person Syndrome + new insights in neuroimmunology, virology & inflammation. Open to all: clinicians, researchers, patients & community!

#Neuroimmunology #CUAnschutz #BrainHealth

🧪Hot off the press: the Beam Lab has published a study titled “Interaction between CaV2.1 and Junctophilin3/4 depends on the II-III loop of CaV2.1 and on the α-helical region of Junctophilin3/4” in the *Journal of Biological Chemistry!🧬📄

🔗 Read Here: tr.ee/oShXGe

🧠👀 New research alert!

We're excited to share a new publication from Dr. Benjamin Scholl: "Coordinated Eye and Head Movements Guide Navigation over Fixation."