Carolina Tropini (TropiniLab@UBC)
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ctropini.bsky.social
Carolina Tropini (TropiniLab@UBC)
@ctropini.bsky.social
Assistant Professor at the University of British Columbia studying the gut microbiota and abiotic environment in health and disease.
http://tropini.microbiology.ubc.ca
Sharing exciting work led by PhD students McCallum and Burckhardt! We created a new series of syn bio tools in Bacteroides to create non-invasive, real time and sensitive in vivo gut biosensors. www.biorxiv.org/content/10.1...
Expanding the Bacteroides synthetic biology toolkit to develop an in vivo intestinal malabsorption biosensor.
The human gut is a highly dynamic physical environment where perturbations - including factors such as acidification, oxygenation, and particle concentration (osmolality) - can influence microbiota co...
www.biorxiv.org
March 20, 2025 at 1:56 PM
Excited to share our latest preprint led by Dr. Hunter! We show that osmotic shifts, common in the gut, alter T4 phage-E. coli evolution. High osmolality promotes fitness but selects for mucoid, weakly phage-resistant E. coli, with implications for phage therapy! biorxiv.org/content/10.1...
Osmotic conditions shape fitness gains and resistance mechanisms during E. coli and T4 phage co-evolution
Bacteriophages, or phages, are viruses that infect bacteria and offer a promising approach to combating antimicrobial resistance in the gut by selectively targeting harmful bacteria while preserving t...
biorxiv.org
March 19, 2025 at 1:19 AM
Excited to share our latest publication by Adel Yavarinasab et al!
February 23, 2025 at 3:43 AM
Very excited to share a new paper in collaboration with the Ciernia lab! We show that early-life inflammation alters sex hormones and mating behavior in mice, alongside shifts in hormone-modifying microbiota members! Great work by Olivia Sullivan, Claire Sie and many others! doi.org/10.1016/j.bb...
Redirecting
doi.org
December 28, 2024 at 3:26 AM