Cassie Simonich
@csimonich.bsky.social
Reposted by Cassie Simonich
In study led by @csimonich.bsky.social & Teagan McMahon, we quantify antigenic evolution of RSV F
Important because:
1️⃣ RSV top cause of infant hospitalization in USA
2️⃣ New antibodies & vax can prevent hospitalizations
3️⃣ Will virus evolution erode their efficacy?
www.biorxiv.org/content/10.1...
Important because:
1️⃣ RSV top cause of infant hospitalization in USA
2️⃣ New antibodies & vax can prevent hospitalizations
3️⃣ Will virus evolution erode their efficacy?
www.biorxiv.org/content/10.1...
RSV F evolution escapes some monoclonal antibodies but does not strongly erode neutralization by human polyclonal sera
Vaccines and monoclonal antibodies targeting the respiratory syncytial virus (RSV) fusion protein (F) have recently begun to be widely used to protect infants and high-risk adults. Some other viral pr...
www.biorxiv.org
March 12, 2025 at 10:31 PM
In study led by @csimonich.bsky.social & Teagan McMahon, we quantify antigenic evolution of RSV F
Important because:
1️⃣ RSV top cause of infant hospitalization in USA
2️⃣ New antibodies & vax can prevent hospitalizations
3️⃣ Will virus evolution erode their efficacy?
www.biorxiv.org/content/10.1...
Important because:
1️⃣ RSV top cause of infant hospitalization in USA
2️⃣ New antibodies & vax can prevent hospitalizations
3️⃣ Will virus evolution erode their efficacy?
www.biorxiv.org/content/10.1...