Cold Spring Harbor Laboratory Press
@cshlpress.bsky.social
The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! tinyurl.com/Genome-Res-3...
November 4, 2025 at 9:23 PM
The new issue of @genomeresearch is now live. Follow the link to new research on wheat centromere adaptation, Quadrupia - a G-quadruplex database, and more! tinyurl.com/Genome-Res-3...
Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not.
Now in print + eBook formats: bit.ly/epigeneticsb...
Now in print + eBook formats: bit.ly/epigeneticsb...
October 21, 2025 at 4:43 PM
Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not.
Now in print + eBook formats: bit.ly/epigeneticsb...
Now in print + eBook formats: bit.ly/epigeneticsb...
Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21. #Epigenetics #MolecularBiology #CellBiology #Genomics
October 17, 2025 at 8:43 PM
Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21. #Epigenetics #MolecularBiology #CellBiology #Genomics
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-3...
October 2, 2025 at 4:39 PM
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-3...
September 3, 2025 at 7:13 PM
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-3...
August 4, 2025 at 4:39 PM
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-3...
New issue of Genes & Development! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: genesdev.cshlp.org/content/39/15-16.toc
August 1, 2025 at 4:44 PM
New issue of Genes & Development! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: genesdev.cshlp.org/content/39/15-16.toc
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-3...
July 2, 2025 at 5:28 PM
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-3...
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-3...
June 3, 2025 at 2:09 PM
The new issue of @genomeresearch.bsky.social is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-3...
Call for Papers! @genomeresearch.bsky.social is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung (Alice) Lee, and Raheleh Rahbari. tinyurl.com/Call-for-pap... #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism
May 7, 2025 at 3:49 PM
Call for Papers! @genomeresearch.bsky.social is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung (Alice) Lee, and Raheleh Rahbari. tinyurl.com/Call-for-pap... #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism
The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-3...
May 5, 2025 at 9:18 PM
The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-3...
SF3B1: from core splicing factor to oncogenic driver — this #RNASpecialIssue article explores how SF3B1-mutant splicing drives cancer, with insights into prognosis, phenotypes & the need for targeted therapies. bit.ly/4bqmRy2
April 17, 2025 at 8:34 PM
SF3B1: from core splicing factor to oncogenic driver — this #RNASpecialIssue article explores how SF3B1-mutant splicing drives cancer, with insights into prognosis, phenotypes & the need for targeted therapies. bit.ly/4bqmRy2
Connecting genotype and phenotype in minor spliceosome diseases.
This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz
This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz
April 15, 2025 at 12:19 AM
Connecting genotype and phenotype in minor spliceosome diseases.
This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz
This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical phenotypes. bit.ly/4bt3aWz
This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer: bit.ly/3F4Sv8g
April 11, 2025 at 3:29 PM
This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer: bit.ly/3F4Sv8g
Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1
April 9, 2025 at 7:37 PM
Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron
April 7, 2025 at 7:10 PM
Exploring the therapeutic potential of modulating nonsense-mediated mRNA decay.
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron
This paper from the #RNASpecialIssue explores promising approaches employed to regulate NMD for therapeutic purposes, and highlights potential challenges in future clinical development. bit.ly/3F86Ron
Alternative splicing (AS) is vital for heart function, and its disruption is linked to disease. This #RNASpecialIssue article highlights nonsplicing roles of AS factors and proposes a novel disease mechanism involving pathogenic RNA granules and disrupted AS factor localization. bit.ly/3DkHM9d
April 2, 2025 at 6:26 PM
Alternative splicing (AS) is vital for heart function, and its disruption is linked to disease. This #RNASpecialIssue article highlights nonsplicing roles of AS factors and proposes a novel disease mechanism involving pathogenic RNA granules and disrupted AS factor localization. bit.ly/3DkHM9d
Cytoplasmic viruses alter nuclear trafficking, causing RNA-binding proteins (RBPs) to relocate and act as antiviral defenses. This article from the #RNASpecialIssue explores host–virus interactions and the unanswered questions about their mechanisms. bit.ly/3QJOjNG
March 31, 2025 at 9:29 PM
Cytoplasmic viruses alter nuclear trafficking, causing RNA-binding proteins (RBPs) to relocate and act as antiviral defenses. This article from the #RNASpecialIssue explores host–virus interactions and the unanswered questions about their mechanisms. bit.ly/3QJOjNG
This article examines how RNA sensors bind ligands and trigger type I interferon-stimulated genes. It also explores how mutations in RNA sensors and RNA homeostasis genes are linked to autoimmune and autoinflammatory diseases. bit.ly/4bowQEb #RNASpecialIssue
March 26, 2025 at 5:20 PM
This article examines how RNA sensors bind ligands and trigger type I interferon-stimulated genes. It also explores how mutations in RNA sensors and RNA homeostasis genes are linked to autoimmune and autoinflammatory diseases. bit.ly/4bowQEb #RNASpecialIssue
Viral quasispecies are dynamic mutant distributions that arise from high RNA replication error rates. This article from the #RNASpecialIssue reviews the molecular basis of mutant swarm formation, its role in viral disease and epidemics, and more: bit.ly/4kovSf0
March 24, 2025 at 8:38 PM
Viral quasispecies are dynamic mutant distributions that arise from high RNA replication error rates. This article from the #RNASpecialIssue reviews the molecular basis of mutant swarm formation, its role in viral disease and epidemics, and more: bit.ly/4kovSf0
This article examines RNA gain-of-function mutations from expanded short tandem repeats (STRs) in developmental and degenerative diseases. It discusses STR roles in RNA processing, their impact on myotonic dystrophy, and relevance to other STR expansion disorders: bit.ly/4igE5jS #RNASpecialIssue
March 20, 2025 at 7:30 PM
This article examines RNA gain-of-function mutations from expanded short tandem repeats (STRs) in developmental and degenerative diseases. It discusses STR roles in RNA processing, their impact on myotonic dystrophy, and relevance to other STR expansion disorders: bit.ly/4igE5jS #RNASpecialIssue
Fragile X syndrome (FXS) is caused by CGG repeat expansion in FMR1, leading to DNA methylation and loss of FMRP. This #RNASpecialIssue paper explores how splice-switching ASOs and kinase inhibition can restore FMR1 expression, offering new therapeutic potential: bit.ly/4i2UpF2 #FragileX #RNAsplicing
March 19, 2025 at 2:59 PM
Fragile X syndrome (FXS) is caused by CGG repeat expansion in FMR1, leading to DNA methylation and loss of FMRP. This #RNASpecialIssue paper explores how splice-switching ASOs and kinase inhibition can restore FMR1 expression, offering new therapeutic potential: bit.ly/4i2UpF2 #FragileX #RNAsplicing
YTHDF2, a key m6A reader, regulates the m6A-modified epitranscriptome in development, stem cell expansion, and immune evasion. This #RNASpecialIssue review explores its mechanisms and therapeutic potential in cancer treatment. Read more: bit.ly/4knZut8
March 17, 2025 at 2:40 PM
YTHDF2, a key m6A reader, regulates the m6A-modified epitranscriptome in development, stem cell expansion, and immune evasion. This #RNASpecialIssue review explores its mechanisms and therapeutic potential in cancer treatment. Read more: bit.ly/4knZut8
Modifications of mitochondrial tRNA (mt-tRNA) are crucial for decoding and stabilizing tRNA. This review from the #RNASpecialIssue examines their roles in disease and emerging therapies. bit.ly/3EYriE3
March 14, 2025 at 2:27 PM
Modifications of mitochondrial tRNA (mt-tRNA) are crucial for decoding and stabilizing tRNA. This review from the #RNASpecialIssue examines their roles in disease and emerging therapies. bit.ly/3EYriE3
The RNA Journal Special Issue on RNA & Disease highlights how subtle RNA changes, modifications, and interactions drive pathology across organs and systems. This month, look out for 15 articles spanning diverse topics, from molecular mechanisms to therapeutic insights. #RNASpecialIssue
March 14, 2025 at 2:22 PM
The RNA Journal Special Issue on RNA & Disease highlights how subtle RNA changes, modifications, and interactions drive pathology across organs and systems. This month, look out for 15 articles spanning diverse topics, from molecular mechanisms to therapeutic insights. #RNASpecialIssue