Chris Said
@csaid.bsky.social
Data science at Propel. Formerly Stitch Fix, Opendoor, Twitter, Facebook, neuroscience. https://x.com/chris_said
https://chris-said.io/
https://chris-said.io/
If folate deficiencies really did cause autism, then you would expect to see a sharp drop in the autism-by-birth-year curve in 1997, when folic acid fortification was mandated.
Instead, the curve continued its upward trend unabated.
chris-said.io/2021/06/27/a...
Instead, the curve continued its upward trend unabated.
chris-said.io/2021/06/27/a...
September 5, 2025 at 7:46 PM
If folate deficiencies really did cause autism, then you would expect to see a sharp drop in the autism-by-birth-year curve in 1997, when folic acid fortification was mandated.
Instead, the curve continued its upward trend unabated.
chris-said.io/2021/06/27/a...
Instead, the curve continued its upward trend unabated.
chris-said.io/2021/06/27/a...
Nate identifies three tenets of Blueskyism: Smalltent-ism, Credentialism, and Catastrophism.
I wish he hadn't written it in such an antagonistic way, but I think he's right.
I wish he hadn't written it in such an antagonistic way, but I think he's right.
September 5, 2025 at 12:41 PM
Nate identifies three tenets of Blueskyism: Smalltent-ism, Credentialism, and Catastrophism.
I wish he hadn't written it in such an antagonistic way, but I think he's right.
I wish he hadn't written it in such an antagonistic way, but I think he's right.
Nate unfortunately uses some of the same style he criticizes Bluesky for, but I agree with overall point.
People here don't realize how alienating this place is to normal voters.
www.natesilver.net/p/what-is-bl...
People here don't realize how alienating this place is to normal voters.
www.natesilver.net/p/what-is-bl...
September 5, 2025 at 12:38 PM
Nate unfortunately uses some of the same style he criticizes Bluesky for, but I agree with overall point.
People here don't realize how alienating this place is to normal voters.
www.natesilver.net/p/what-is-bl...
People here don't realize how alienating this place is to normal voters.
www.natesilver.net/p/what-is-bl...
The boring but underappreciated reality is that if you don't want authoritarians taking power, you need to come closer to median voter opinions on crime and immigration.
September 4, 2025 at 12:33 PM
The boring but underappreciated reality is that if you don't want authoritarians taking power, you need to come closer to median voter opinions on crime and immigration.
Yup that history is actually a motivation in the article I linked. But keep reading to see why this time might be very different.
August 27, 2025 at 3:26 AM
Yup that history is actually a motivation in the article I linked. But keep reading to see why this time might be very different.
DOGE now doing what it should have been doing instead of firing federal employees randomly for no reason.
marginalrevolution.com/marginalrevo...
marginalrevolution.com/marginalrevo...
July 26, 2025 at 6:33 PM
DOGE now doing what it should have been doing instead of firing federal employees randomly for no reason.
marginalrevolution.com/marginalrevo...
marginalrevolution.com/marginalrevo...
ChatGPT’s water usage is “probably the last worry you should have about either water or AI”
www.slowboring.com/p/theres-ple...
www.slowboring.com/p/theres-ple...
July 22, 2025 at 10:36 AM
ChatGPT’s water usage is “probably the last worry you should have about either water or AI”
www.slowboring.com/p/theres-ple...
www.slowboring.com/p/theres-ple...
[Work opportunity] In the wake of OBBB, Propel is opening up a residency program for exceptional mid-career technologists to help states navigate policy implementation around SNAP, Medicaid, TANF, and WIC.
July 11, 2025 at 2:22 PM
[Work opportunity] In the wake of OBBB, Propel is opening up a residency program for exceptional mid-career technologists to help states navigate policy implementation around SNAP, Medicaid, TANF, and WIC.
This might have been the quickest I've gone from "that's an insane conspiracy theory" to "it's plausible".
June 13, 2025 at 4:04 PM
This might have been the quickest I've gone from "that's an insane conspiracy theory" to "it's plausible".
I wrote this a while back. I just don’t think the science should matter as much as we might want it to.
May 20, 2025 at 10:31 AM
I wrote this a while back. I just don’t think the science should matter as much as we might want it to.
I don't know about Ahmari, but @hananiarichard.bsky.social is genuinely disgusted by the stupidity of MAGA (even if he trolls a bit)
All his tweets are like this.
All his tweets are like this.
May 18, 2025 at 6:36 PM
I don't know about Ahmari, but @hananiarichard.bsky.social is genuinely disgusted by the stupidity of MAGA (even if he trolls a bit)
All his tweets are like this.
All his tweets are like this.
I don't know about Ahmari, but @hananiarichard.bsky.social is genuinely disgusted by the stupidity of MAGA (even if he trolls a bit)
All his tweets are like this.
All his tweets are like this.
May 18, 2025 at 6:35 PM
I don't know about Ahmari, but @hananiarichard.bsky.social is genuinely disgusted by the stupidity of MAGA (even if he trolls a bit)
All his tweets are like this.
All his tweets are like this.
Many people here say there's no need for Dems to build a bigger tent, since MAGA will destroy the economy and lose elections on fundamentals.
Maybe, but I wouldn't bank on it! It's not that hard for Trump to just stop doing dumb things.
Maybe, but I wouldn't bank on it! It's not that hard for Trump to just stop doing dumb things.
April 23, 2025 at 1:46 PM
Many people here say there's no need for Dems to build a bigger tent, since MAGA will destroy the economy and lose elections on fundamentals.
Maybe, but I wouldn't bank on it! It's not that hard for Trump to just stop doing dumb things.
Maybe, but I wouldn't bank on it! It's not that hard for Trump to just stop doing dumb things.
If you want to beat Trump, the way you respond to these types of posts is an IQ test.
April 20, 2025 at 6:44 PM
If you want to beat Trump, the way you respond to these types of posts is an IQ test.
“Bhutan is unusually happy” is a popular claim that, in retrospect, had all the hallmarks of being false.
x.com/ourworldinda...
x.com/ourworldinda...
March 27, 2025 at 10:35 AM
“Bhutan is unusually happy” is a popular claim that, in retrospect, had all the hallmarks of being false.
x.com/ourworldinda...
x.com/ourworldinda...
Do the terms "credit" and "debit" add anything other than confusion?
Why is an increase to an account a "credit" or "debit" depending on which side of the equation it's on?
Why not just say "increase" and "decrease?
Why is an increase to an account a "credit" or "debit" depending on which side of the equation it's on?
Why not just say "increase" and "decrease?
March 22, 2025 at 7:18 PM
Do the terms "credit" and "debit" add anything other than confusion?
Why is an increase to an account a "credit" or "debit" depending on which side of the equation it's on?
Why not just say "increase" and "decrease?
Why is an increase to an account a "credit" or "debit" depending on which side of the equation it's on?
Why not just say "increase" and "decrease?
Interesting prediction on AI and unemployment. www.astralcodexten.com/p/links-for-...
February 28, 2025 at 2:44 AM
Interesting prediction on AI and unemployment. www.astralcodexten.com/p/links-for-...
One of the creators of the USDS writes about DOGE.
"I care deeply about trans people and immigrants [...] but I could not care less that someone plugged in a server to create a new email list without a Privacy Impact Assessment."
reason.com/2025/02/13/i...
"I care deeply about trans people and immigrants [...] but I could not care less that someone plugged in a server to create a new email list without a Privacy Impact Assessment."
reason.com/2025/02/13/i...
February 13, 2025 at 5:40 PM
One of the creators of the USDS writes about DOGE.
"I care deeply about trans people and immigrants [...] but I could not care less that someone plugged in a server to create a new email list without a Privacy Impact Assessment."
reason.com/2025/02/13/i...
"I care deeply about trans people and immigrants [...] but I could not care less that someone plugged in a server to create a new email list without a Privacy Impact Assessment."
reason.com/2025/02/13/i...
Shoplifting by political affiliation.
I don't want to read too much into this, but I'm not surprised by how this sorts.
I got this data from a survey of ACX readers. www.astralcodexten.com/p/acx-survey...
I don't want to read too much into this, but I'm not surprised by how this sorts.
I got this data from a survey of ACX readers. www.astralcodexten.com/p/acx-survey...
January 29, 2025 at 7:50 PM
Shoplifting by political affiliation.
I don't want to read too much into this, but I'm not surprised by how this sorts.
I got this data from a survey of ACX readers. www.astralcodexten.com/p/acx-survey...
I don't want to read too much into this, but I'm not surprised by how this sorts.
I got this data from a survey of ACX readers. www.astralcodexten.com/p/acx-survey...
Someone should start a GoFundMe for any former administration officials who had their security detail removed.
January 24, 2025 at 1:59 PM
Someone should start a GoFundMe for any former administration officials who had their security detail removed.
If these results are true, standard clinical practice guidelines around NSAIDs for acute back pain have been causing chronic pain for millions of people.
I'd love to see a human RCT around this, but in the meantime, I'll stick to Tylenol instead of NSAIDs.
I'd love to see a human RCT around this, but in the meantime, I'll stick to Tylenol instead of NSAIDs.
January 12, 2025 at 7:17 PM
If these results are true, standard clinical practice guidelines around NSAIDs for acute back pain have been causing chronic pain for millions of people.
I'd love to see a human RCT around this, but in the meantime, I'll stick to Tylenol instead of NSAIDs.
I'd love to see a human RCT around this, but in the meantime, I'll stick to Tylenol instead of NSAIDs.
And similar to the results in humans, analgesics without anti-inflammatory properties (red, purple, blue) were good in the long term.
Only the anti-inflammatory (green) was bad in the long term.
Only the anti-inflammatory (green) was bad in the long term.
January 12, 2025 at 7:17 PM
And similar to the results in humans, analgesics without anti-inflammatory properties (red, purple, blue) were good in the long term.
Only the anti-inflammatory (green) was bad in the long term.
Only the anti-inflammatory (green) was bad in the long term.
A pure anti-inflammatory diclofenac (green) showed identical results. Just like dexamethasone, it was better than saline in the short term, and worse in the long term.
January 12, 2025 at 7:17 PM
A pure anti-inflammatory diclofenac (green) showed identical results. Just like dexamethasone, it was better than saline in the short term, and worse in the long term.
If that's not enough evidence, the paper also did a randomized experiment on mice.
Compared to saline, a drug with anti-inflammatory properties (dexamethasone) drove short term pain relief but made things worse in the long term.
Compared to saline, a drug with anti-inflammatory properties (dexamethasone) drove short term pain relief but made things worse in the long term.
January 12, 2025 at 7:17 PM
If that's not enough evidence, the paper also did a randomized experiment on mice.
Compared to saline, a drug with anti-inflammatory properties (dexamethasone) drove short term pain relief but made things worse in the long term.
Compared to saline, a drug with anti-inflammatory properties (dexamethasone) drove short term pain relief but made things worse in the long term.
This is observational data so obviously there could be residual confounding. But what’s interesting is that there was no increased risk from non-anti-inflammatory like Paracetamol (Tylenol).
Only the anti-inflammatories had higher risk.
Only the anti-inflammatories had higher risk.
January 12, 2025 at 7:17 PM
This is observational data so obviously there could be residual confounding. But what’s interesting is that there was no increased risk from non-anti-inflammatory like Paracetamol (Tylenol).
Only the anti-inflammatories had higher risk.
Only the anti-inflammatories had higher risk.