Claire Rougeulle
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crougeulle.bsky.social
Claire Rougeulle
@crougeulle.bsky.social
530 followers 52 following 9 posts
Director of Institut Curie research center
Group leader, X chromosome lover, Epigenetics, Development, ncRNA
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Reposted by Claire Rougeulle
institutcurie.bsky.social
▶️ Pour en savoir plus
⏩ Lire l'actu : curie.fr/actualite/di...
⏩ Lire la publication : www.nature.com/articles/s41...
DNA methylation influences human centromere positioning and function - Nature Genetics
Genome-wide and targeted perturbation of DNA methylation at centromeres affects CENP-A positioning and centromere structure, resulting in aneuploidy and reduced cell viability.
www.nature.com
September 4, 2025 at 12:37 PM
Reposted by Claire Rougeulle
paveltomancak.bsky.social
We had #four interdisciplinary teams, integrating dev-bio, evolution, tissue mechanics, and biophysical modeling, all going full throttle to understand the #CF. Still, it took more than 7 years to publish two papers back-to-back (10/12)

www.nature.com/articles/s41...
www.nature.com/articles/s41...
Patterned invagination prevents mechanical instability during gastrulation - Nature
In Drosophila, the cephalic furrow counteracts mechanical stress as the developing head and the trunk tissues meet, providing evidence for how mechanical forces influence the evolution of morphog...
www.nature.com
September 4, 2025 at 8:22 AM