Kevin Frank, MD
@criticalgestalt.bsky.social
EM/IM/CC, advanced critical care echo and critical care TEE diplomate and enthusiast. Bluegrass mandolin enthusiast.
Seems more like a neostigmine plus miralax drip sort of day, but colace is a choice…
October 7, 2025 at 12:18 AM
Seems more like a neostigmine plus miralax drip sort of day, but colace is a choice…
Several studies using LUS to guide diuresis have been positive, and it’s just as simple to look at, and has also been shown to be a good surrogate for LAP (though VeXUS plus LUS plus LV function and VTI is my own practice to guide decision making). This was poorly thought out imo.
September 17, 2025 at 3:36 AM
Several studies using LUS to guide diuresis have been positive, and it’s just as simple to look at, and has also been shown to be a good surrogate for LAP (though VeXUS plus LUS plus LV function and VTI is my own practice to guide decision making). This was poorly thought out imo.
DOI: 10.1016/j.chest.2024.06.1618, pmids 38465145 and 37265888. Hope it helps!
July 11, 2025 at 12:14 AM
DOI: 10.1016/j.chest.2024.06.1618, pmids 38465145 and 37265888. Hope it helps!
Some case reports of methylene blue plus hydroxycobalamin are promising. But yes.
July 11, 2025 at 12:06 AM
Some case reports of methylene blue plus hydroxycobalamin are promising. But yes.
I feel like 2025 is more IVC plus VeXUS plus lung u/s plus echo (vti and E/e’ as a surrogate for wedge, specifically). But I’m a fancy boi, so.
July 8, 2025 at 3:34 AM
I feel like 2025 is more IVC plus VeXUS plus lung u/s plus echo (vti and E/e’ as a surrogate for wedge, specifically). But I’m a fancy boi, so.
With hazard ratios like this, it’s pretty obvious the study was underpowered. Curious why the authors didn’t try to amend it for additional patients after an interim analysis.
June 15, 2025 at 12:17 AM
With hazard ratios like this, it’s pretty obvious the study was underpowered. Curious why the authors didn’t try to amend it for additional patients after an interim analysis.
Seems like a lot of the references come back to Edelstein’s 1995 article from Clinical Infectious Diseases.
Antimicrobial Chemotherapy for Legionnaires' Disease: A Review
Abstract. Controlled trials of antimicrobialchemotherapy for legionnaires' diseasehave not been performed, although erythromycin and tetracycline appear to
https://academic.oup.com/cid/article-abstract/21/Supplement_3/S265/318838?redirectedFrom=fulltext&login=true#no-access-message#no-access-message
April 16, 2025 at 1:37 AM
Seems like a lot of the references come back to Edelstein’s 1995 article from Clinical Infectious Diseases.
Sanford guide agrees (and Hopkins abx).
April 16, 2025 at 1:02 AM
Sanford guide agrees (and Hopkins abx).
Especially for LV function in critical illness, MAPSE rocks.
December 5, 2024 at 11:40 PM
Especially for LV function in critical illness, MAPSE rocks.