Cristina González-Correa
@cristinagcorrea.bsky.social
phD candidate in cardiovascular pharmacology (University of Granada) | Exploring microbiome-host interactions in cardiovascular disease🫀🦠💊
Congrats to everyone fot this team effort! @universidadgranada.bsky.social
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January 27, 2026 at 5:21 PM
Congrats to everyone fot this team effort! @universidadgranada.bsky.social
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Overall, our results suggest that targeting the gut microbiota could boost the efficacy of diuretics and improve hypertension management, without adding extra drug-related side effects. 🚀
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January 27, 2026 at 5:21 PM
Overall, our results suggest that targeting the gut microbiota could boost the efficacy of diuretics and improve hypertension management, without adding extra drug-related side effects. 🚀
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These effects were linked to changes in the gut microbiota and its metabolites (like acetate). Interestingly, part of the benefit could be transferred via fecal microbiota transplantation → pointing to a microbiota-dependent mechanism.
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January 27, 2026 at 5:21 PM
These effects were linked to changes in the gut microbiota and its metabolites (like acetate). Interestingly, part of the benefit could be transferred via fecal microbiota transplantation → pointing to a microbiota-dependent mechanism.
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Furthermore, the HCTZ + LC40-treated rats exhibited reduced neuroinflammation and sympathetic activity, along with an immunoregulatory effect characterized by increased regulatory T cell infiltration and a reduction of vascular oxidative stress in the aorta.
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January 27, 2026 at 5:21 PM
Furthermore, the HCTZ + LC40-treated rats exhibited reduced neuroinflammation and sympathetic activity, along with an immunoregulatory effect characterized by increased regulatory T cell infiltration and a reduction of vascular oxidative stress in the aorta.
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The combination potentiated the blood pressure–lowering effect and improved endothelial dysfunction — without changing drug levels or electrolyte balance.
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January 27, 2026 at 5:21 PM
The combination potentiated the blood pressure–lowering effect and improved endothelial dysfunction — without changing drug levels or electrolyte balance.
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In our study, we combined hydrochlorothiazide with a probiotic strain (Limosilactobacillus fermentum CECT5716) in hypertensive rats.
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January 27, 2026 at 5:21 PM
In our study, we combined hydrochlorothiazide with a probiotic strain (Limosilactobacillus fermentum CECT5716) in hypertensive rats.
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Hypertension is still one of the main cardiovascular risk factors, and many patients don’t achieve good control with current treatments. What if the gut microbiota could help?
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January 27, 2026 at 5:21 PM
Hypertension is still one of the main cardiovascular risk factors, and many patients don’t achieve good control with current treatments. What if the gut microbiota could help?
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