Chris Humphries
@cphumphries.bsky.social
Emergency medicine, clinical toxicology, regenerative medicine. Translational projects from benchtop to patient. Edinburgh, UK.
Our trial protocol is out - first-in-human allogeneic macrophages for the treatment of paracetamol liver injury. Can they fill the gap between acetylcysteine and transplant? bmjopen.bmj.com/content/14/1...
Macrophage Therapy for Acute Liver Injury (MAIL): a study protocol for a phase 1 randomised, open-label, dose-escalation study to evaluate safety, tolerability and activity of allogeneic alternatively...
Introduction Acute liver failure (ALF) has no effective treatment other than liver transplantation and is commonly caused by paracetamol overdose. New treatments are needed to treat and prevent ALF. A...
bmjopen.bmj.com
December 11, 2024 at 11:46 AM
Our trial protocol is out - first-in-human allogeneic macrophages for the treatment of paracetamol liver injury. Can they fill the gap between acetylcysteine and transplant? bmjopen.bmj.com/content/14/1...
My opening Bluesky offer - for anyone interested in how we're pushing the boundaries of research into paracetamol (acetaminophen) poisoning, take a look at our recent article here: link.springer.com/article/10.1...
(Trial protocol due out soon!)
(Trial protocol due out soon!)
The emerging role of alternatively activated macrophages to treat acute liver injury - Archives of Toxicology
Acute liver injury (ALI) has a clear requirement for novel therapies. One emerging option is the use of alternatively activated macrophages (AAMs); a distinct subtype of macrophage with a role in live...
link.springer.com
November 14, 2024 at 8:56 PM
My opening Bluesky offer - for anyone interested in how we're pushing the boundaries of research into paracetamol (acetaminophen) poisoning, take a look at our recent article here: link.springer.com/article/10.1...
(Trial protocol due out soon!)
(Trial protocol due out soon!)