Conor McCann
@conormccann-ens.bsky.social
Principal Investigator at UCL in Enteric Nervous System Development and Stem Cell Therapy. All views my own
https://www.ucl.ac.uk/child-health/conor-mccanns-research-group
https://www.ucl.ac.uk/child-health/conor-mccanns-research-group
Hot on the heels of our recent basic science preprint. Check out our preprint of a data driven study looking at Hirschsprung Disease Outcomes of children in England using ECHILD (medrxiv.org/cgi/content/...).
Childhood outcomes in children with Hirschsprung disease: a population-based data linkage study in England
Objective Hirschsprung disease (HSCR) is a rare congenital intestinal condition that, despite lifesaving surgery, can result in increased hospitalisations and a lower quality of life throughout childh...
medrxiv.org
October 20, 2025 at 10:28 AM
Hot on the heels of our recent basic science preprint. Check out our preprint of a data driven study looking at Hirschsprung Disease Outcomes of children in England using ECHILD (medrxiv.org/cgi/content/...).
Check out our lab’s new preprint (www.biorxiv.org/content/10.1...) on the consequences of ENS progenitor transplantation to mouse Hirschsprung disease explants. Delighted to continue a fruitful collaboration with
@tsakiridis.bsky.social
to develop a #celltherapy for #Hirschsprungs
@tsakiridis.bsky.social
to develop a #celltherapy for #Hirschsprungs
Functional and molecular rescue of aganglionic colon by human enteric nervous system progenitor transplantation in Hirschsprung disease
Hirschsprung disease (HSCR) is a devastating congenital disorder characterised by absence of the enteric nervous system (ENS) in the distal gut. Cell therapy, using human pluripotent stem cell-derived...
www.biorxiv.org
October 17, 2025 at 11:08 AM
Check out our lab’s new preprint (www.biorxiv.org/content/10.1...) on the consequences of ENS progenitor transplantation to mouse Hirschsprung disease explants. Delighted to continue a fruitful collaboration with
@tsakiridis.bsky.social
to develop a #celltherapy for #Hirschsprungs
@tsakiridis.bsky.social
to develop a #celltherapy for #Hirschsprungs
For the fourth year running, our INSPIRE Programme (hdbi.org/inspire) is welcoming A-level students to @uclchildhealth.bsky.social this week. This has been possible thanks to Wellcome Trust and Human Developmental Initiative funding, and all our volunteers. #workexperience #childheath #research
INSPIRE Programme — HDBI - Human Development Biology Initiative
hdbi.org
July 14, 2025 at 6:51 AM
For the fourth year running, our INSPIRE Programme (hdbi.org/inspire) is welcoming A-level students to @uclchildhealth.bsky.social this week. This has been possible thanks to Wellcome Trust and Human Developmental Initiative funding, and all our volunteers. #workexperience #childheath #research
New preprint from our group on bioRxiv, a little step towards a better understanding of how coordinated contractions develop in the human intestine. Please check it out and let us know your thoughts.
Purinergic signalling and calcium dynamics: potential drivers in the onset of coordinated intestinal motility in human fetal development https://www.biorxiv.org/content/10.1101/2025.04.17.649306v1
April 20, 2025 at 11:27 AM
New preprint from our group on bioRxiv, a little step towards a better understanding of how coordinated contractions develop in the human intestine. Please check it out and let us know your thoughts.
Reposted by Conor McCann
Second (BBSRC Yorkshire Bioscience DTP-funded) PhD project available in our lab (jointly with
@christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...
@christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...
Funded PhD Project in stem cells, mechanobiology and developmental biology - the Node
A BBSRC Yorkshire Bioscience DTP-funded PhD project (jointly with the group of Chris Toseland) focusing on the role of biomechanical cues in embryonic cell fate decisions using human pluripotent stem ...
thenode.biologists.com
November 18, 2024 at 3:17 PM
Second (BBSRC Yorkshire Bioscience DTP-funded) PhD project available in our lab (jointly with
@christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...
@christoseland.bsky.social) examining how biomechanical cues crosstalk with signals to influence cell fate decisions during hESC differentiation. More details here: thenode.biologists.com/jobs/funded-...