Halloween card?!

And the INCREDIBLE biophysics and bioEM facilities and protein production facility (Niko and Roman)

This production was the result of a huge team effort from the members of @cellarchlab.com, Maier lab, Lim lab, Hiller lab and our neighbor Basile Wicky!

Thanks Oli! And yes the resemblance is uncanny 🔮

Yes it’s a midi shell, I’ll think about how to rephrase/present it better before submitting :)

I am in a cryo-ET lab now so hoping to figure it out!

Next step U-ExM!!

Shout out to the amazing team working on this @ghooger.bsky.social, Ophelia, Evan, Simone, Axel and my PhD advisors David Taylor and @edwardmarcotte.bsky.social for always encouraging me to explore!!!

We have renamed it to CAGE: Conserved Assembly in Gram-negative bacteria and Eukaryotes; because in addition to shape, it has crazy phylogeny!! And to quote the paper: “The CAGE complex stands as both a new structural archetype and a reminder that the molecular universe is far from fully charted.”

When I first saw it in my micrographs, I thought it looked like a Philadelphia pretzel. After years of explaining a Philly pretzel and receiving endless pretzel pictures (s/o Jamie) and pretzel swag (s/o @sofie-dot-rec.bsky.social)….

The early days looking at this complex were spent with @ghooger.bsky.social on the JEOL 2010F in the basement of UT Austin during the pandemic (while watching Real Housewives)