Cobus Smit
cobussmit.bsky.social
Cobus Smit
@cobussmit.bsky.social
Reposted by Cobus Smit
So pleased to share this work on alkaloid biosynthesis.
Great collaboration with @unsworthchem.bsky.social. Well done to all authors. We have found key alkaloid producing enzymes that look like those normally found in bacteria.

www.york.ac.uk/news-and-eve...
January 15, 2026 at 10:10 AM
Reposted by Cobus Smit
New paper out today on alkaloid (bio)synthesis with @unsworthchem.bsky.social . Dr Lachlan Waddell made ten bioactive securinine alkaloids using "biomimetic" total synthesis - a strategy that we think is analogous to the plant makes the alkaloids by biosynthesis. pubs.rsc.org/en/content/a...
Biomimetic Total Synthesis of Ten Securinega Alkaloids
The Securinega alkaloids are a diverse family of polycyclic alkaloids with broad biological importance. In this study, a formal [4+2] cycloaddition strategy has been used to complete the biomimetic to...
pubs.rsc.org
January 13, 2026 at 5:16 PM
Reposted by Cobus Smit
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5th Synthetic Biology of Natural Products Conference
📅Date: 01 - 04 November 2026
🌏Location: Playa del Carmen, Mexico
📢Early Bird & Talk Submission: 04 May 2026
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January 10, 2026 at 8:12 PM