Caleb Mahlen
@cmahlen.bsky.social
URMC MSTP neuroscience noob
Studying pain physiology and pathology with psychophysics and fMRI
Regis University '22 BS math + neuro
Studying pain physiology and pathology with psychophysics and fMRI
Regis University '22 BS math + neuro
This meta analysis shows there is no change in serum urea or creatinine, which you would expect to see if creatine were causing renal damage. I haven't read this literature as carefully because I don't have kidney disease, but it seems like the wsj article is right
pubmed.ncbi.nlm.nih.gov/31375416/
pubmed.ncbi.nlm.nih.gov/31375416/
Effects of Creatine Supplementation on Renal Function: A Systematic Review and Meta-Analysis - PubMed
Creatine supplements are intended to improve performance, but there are indications that it can overwhelm liver and kidney functions, reduce the quality of life, and increase mortality. Therefore, thi...
pubmed.ncbi.nlm.nih.gov
May 14, 2025 at 4:00 PM
This meta analysis shows there is no change in serum urea or creatinine, which you would expect to see if creatine were causing renal damage. I haven't read this literature as carefully because I don't have kidney disease, but it seems like the wsj article is right
pubmed.ncbi.nlm.nih.gov/31375416/
pubmed.ncbi.nlm.nih.gov/31375416/
It's not a protein, it's similar in size to single amino acids, which are of course absorbed into the blood by the GI tract. Cells have a Na/Cl-dependent creatine transporter (CRT) that transports it from the blood/interstitium to the cell. Hope this helps
May 14, 2025 at 12:32 PM
It's not a protein, it's similar in size to single amino acids, which are of course absorbed into the blood by the GI tract. Cells have a Na/Cl-dependent creatine transporter (CRT) that transports it from the blood/interstitium to the cell. Hope this helps
I agree that the evidence cited in the article was weak. Instead, they should have linked one of the several meta analyses or systematic reviews showing that creatine improves strength in general and in a number of specific populations. Like this one for example pubmed.ncbi.nlm.nih.gov/39519498/
Effects of Creatine Supplementation and Resistance Training on Muscle Strength Gains in Adults <50 Years of Age: A Systematic Review and Meta-Analysis - PubMed
<p>In comparison with a placebo, creatine supplementation combined with resistance training significantly increased upper-body (WMD = 4.43 kg, <i>p</i> < 0.001) and lower-body strength (WMD = 11.35 kg...
pubmed.ncbi.nlm.nih.gov
May 14, 2025 at 12:26 PM
I agree that the evidence cited in the article was weak. Instead, they should have linked one of the several meta analyses or systematic reviews showing that creatine improves strength in general and in a number of specific populations. Like this one for example pubmed.ncbi.nlm.nih.gov/39519498/
Cool study, clickbait description. Sucralose’s effect on appetite was the same as water (fig 6e). Yes, it increased hypothalamic blood flow, but hypothalamic blood flow is unrelated to change in hunger for sucralose (7b).
Sucralose only increases appetite as much as water does!
Sucralose only increases appetite as much as water does!
March 27, 2025 at 12:14 PM
Cool study, clickbait description. Sucralose’s effect on appetite was the same as water (fig 6e). Yes, it increased hypothalamic blood flow, but hypothalamic blood flow is unrelated to change in hunger for sucralose (7b).
Sucralose only increases appetite as much as water does!
Sucralose only increases appetite as much as water does!
Amazing. Almost 10% of the city’s population!
March 22, 2025 at 1:14 AM
Amazing. Almost 10% of the city’s population!
Yes, Colombia is sending their own plane to pick them up, rather than having them delivered in a US military plane in shackles.
The lack of dignity and maltreatment was actually the original complaint of their president, not the tariffs, as the headlines suggest
apnews.com/article/colo...
The lack of dignity and maltreatment was actually the original complaint of their president, not the tariffs, as the headlines suggest
apnews.com/article/colo...
White House says Colombia agrees to take deported migrants after Trump tariff showdown
The White House claimed victory in a showdown with Colombia over accepting flights of deported migrants from the U.S., hours after President Donald Trump threatened steep tariffs.
apnews.com
January 28, 2025 at 2:58 PM
Yes, Colombia is sending their own plane to pick them up, rather than having them delivered in a US military plane in shackles.
The lack of dignity and maltreatment was actually the original complaint of their president, not the tariffs, as the headlines suggest
apnews.com/article/colo...
The lack of dignity and maltreatment was actually the original complaint of their president, not the tariffs, as the headlines suggest
apnews.com/article/colo...