Jordan Shavit
@clot1.bsky.social
Dorfman Professor of Pediatrics, Human Genetics. Research and care of the genetics of blood and cardiovascular disorders at the U. of Michigan. (he/him). OAMO.
I heard about this from @sequenceman.bsky.social today, very exciting to see @chrmosimann.bsky.social getting these out there!
February 7, 2025 at 10:27 PM
I heard about this from @sequenceman.bsky.social today, very exciting to see @chrmosimann.bsky.social getting these out there!
I see the Voltron lions.
February 7, 2025 at 10:22 PM
I see the Voltron lions.
Reposted by Jordan Shavit
This is unexpected but not unheard of, and has been observed in a few other contexts. @clot1.bsky.social 's group recently reported a similar finding on thrombosis in zebrafish:
doi.org/10.1101/2024....
We think there is another critical estradiol target that awaits characterization.
doi.org/10.1101/2024....
We think there is another critical estradiol target that awaits characterization.
Hormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish
Venous thrombosis is a well-known complication of sex hormone therapy, with onset typically within weeks to months after initiation. Worldwide, more than 100 million pre-menopausal women use combined ...
doi.org
February 6, 2025 at 9:57 AM
This is unexpected but not unheard of, and has been observed in a few other contexts. @clot1.bsky.social 's group recently reported a similar finding on thrombosis in zebrafish:
doi.org/10.1101/2024....
We think there is another critical estradiol target that awaits characterization.
doi.org/10.1101/2024....
We think there is another critical estradiol target that awaits characterization.