@clinimmsoc.bsky.social
The Clinical Immunology Society (CIS) aims to support & advance the community of immunology.
clinimmsoc.org
https://linktr.ee/clinicalimmunologysociety
clinimmsoc.org
https://linktr.ee/clinicalimmunologysociety
This Thanksgiving, we want to express our gratitude to this amazing community. Thank you for your contributions and for the collaborative spirit that makes CIS so special.
November 27, 2025 at 7:15 PM
This Thanksgiving, we want to express our gratitude to this amazing community. Thank you for your contributions and for the collaborative spirit that makes CIS so special.
Recognize a mentor you are thankful for!
The Clinical Immunology Society (CIS) Foundation invites you to participate in its "Recognize a Mentor" program. This is an initiative to celebrate the mentors who guide and inspire us.
Honor Your Mentor Here: https://lnkd.in/gQSUxmuR
The Clinical Immunology Society (CIS) Foundation invites you to participate in its "Recognize a Mentor" program. This is an initiative to celebrate the mentors who guide and inspire us.
Honor Your Mentor Here: https://lnkd.in/gQSUxmuR
November 26, 2025 at 8:01 PM
Recognize a mentor you are thankful for!
The Clinical Immunology Society (CIS) Foundation invites you to participate in its "Recognize a Mentor" program. This is an initiative to celebrate the mentors who guide and inspire us.
Honor Your Mentor Here: https://lnkd.in/gQSUxmuR
The Clinical Immunology Society (CIS) Foundation invites you to participate in its "Recognize a Mentor" program. This is an initiative to celebrate the mentors who guide and inspire us.
Honor Your Mentor Here: https://lnkd.in/gQSUxmuR
Reposted
Leniolisib reduced lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome. New study from Chopie Hassan, Kevin S. Thorneloe (Pharming Group) and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
November 24, 2025 at 3:15 PM
Leniolisib reduced lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome. New study from Chopie Hassan, Kevin S. Thorneloe (Pharming Group) and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
Application Deadline Extended!
The application deadline for the CIS–Grifols AIM Workshop is now December 8th.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
The application deadline for the CIS–Grifols AIM Workshop is now December 8th.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
November 21, 2025 at 9:30 PM
Application Deadline Extended!
The application deadline for the CIS–Grifols AIM Workshop is now December 8th.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
The application deadline for the CIS–Grifols AIM Workshop is now December 8th.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
Our search for diagnostic tools for primary immune regulatory disorders (PIRD) continues. Join us in reading this outstanding article by Harris et al.: “T-cell and autoantibody profiling for primary immune regulatory disorders”
https://www.jacionline.org/article/S0091-6749(25)00649-9/abstract
https://www.jacionline.org/article/S0091-6749(25)00649-9/abstract
November 21, 2025 at 7:19 PM
Our search for diagnostic tools for primary immune regulatory disorders (PIRD) continues. Join us in reading this outstanding article by Harris et al.: “T-cell and autoantibody profiling for primary immune regulatory disorders”
https://www.jacionline.org/article/S0091-6749(25)00649-9/abstract
https://www.jacionline.org/article/S0091-6749(25)00649-9/abstract
Reposted
New review from Voyer, @casanovalab.bsky.social, & @anne-puel.bsky.social synthesizes human inborn errors of the alternative NF-κB pathway, highlighting their shared and distinct effects on lymphoid development, immune dysregulation, and mTEC-mediated tolerance rupress.org/jhi/article/...
November 21, 2025 at 5:00 PM
New review from Voyer, @casanovalab.bsky.social, & @anne-puel.bsky.social synthesizes human inborn errors of the alternative NF-κB pathway, highlighting their shared and distinct effects on lymphoid development, immune dysregulation, and mTEC-mediated tolerance rupress.org/jhi/article/...
⏳ TIME IS RUNNING OUT! ⏳
The deadline to submit your abstract for the #CIS2026 Annual Meeting is December 8th.
Don't miss your chance to present in New Orleans.
🔗 Submit today: https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#ClinicalImmunology #Abstracts #MedicalResearch
The deadline to submit your abstract for the #CIS2026 Annual Meeting is December 8th.
Don't miss your chance to present in New Orleans.
🔗 Submit today: https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#ClinicalImmunology #Abstracts #MedicalResearch
November 20, 2025 at 7:07 PM
⏳ TIME IS RUNNING OUT! ⏳
The deadline to submit your abstract for the #CIS2026 Annual Meeting is December 8th.
Don't miss your chance to present in New Orleans.
🔗 Submit today: https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#ClinicalImmunology #Abstracts #MedicalResearch
The deadline to submit your abstract for the #CIS2026 Annual Meeting is December 8th.
Don't miss your chance to present in New Orleans.
🔗 Submit today: https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#ClinicalImmunology #Abstracts #MedicalResearch
Reposted
See a short video summary of the study by Kristine Jeganathan: youtu.be/7Kut4zWWTuk
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November 17, 2025 at 3:15 PM
See a short video summary of the study by Kristine Jeganathan: youtu.be/7Kut4zWWTuk
Reposted
New study from Hassan et al. examines the efficacy of leniolisib, a selective PI3Kδ inhibitor, in a murine model of ALPS, illustrating a reduction in lymphoproliferation and disease-associated biomarkers such as elevated double-negative T cells. rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
November 17, 2025 at 5:00 PM
New study from Hassan et al. examines the efficacy of leniolisib, a selective PI3Kδ inhibitor, in a murine model of ALPS, illustrating a reduction in lymphoproliferation and disease-associated biomarkers such as elevated double-negative T cells. rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
Reposted
IRF4 haploinsufficiency in a multiplex family with Whipple's disease. New report from Sinem Ünal, Stéphanie Dublanc, Jacinta Bustamante, Jérémie Rosain (@jrosain.bsky.social) and colleagues @hopitalnecker.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
November 18, 2025 at 2:45 PM
IRF4 haploinsufficiency in a multiplex family with Whipple's disease. New report from Sinem Ünal, Stéphanie Dublanc, Jacinta Bustamante, Jérémie Rosain (@jrosain.bsky.social) and colleagues @hopitalnecker.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
Reposted
Fournier @hopitalnecker.bsky.social, Poirier, Ebstein et al. report that novel dominant PSMB10 variants cause severe combined immunodeficiency and life-threatening liver disease in three pediatric patients. rupress.org/jhi/article/...
#InbornErrorsOfImmunity #SevereImmunodeficiencies
#InbornErrorsOfImmunity #SevereImmunodeficiencies
November 18, 2025 at 5:01 PM
Fournier @hopitalnecker.bsky.social, Poirier, Ebstein et al. report that novel dominant PSMB10 variants cause severe combined immunodeficiency and life-threatening liver disease in three pediatric patients. rupress.org/jhi/article/...
#InbornErrorsOfImmunity #SevereImmunodeficiencies
#InbornErrorsOfImmunity #SevereImmunodeficiencies
Reposted
In a new research letter, Materna, @vbeziat.bsky.social et al. identified six individuals with homozygous truncating variants in the pre-TCRα intracellular tail, revealing hypomorphic and neutral alleles. rupress.org/jhi/article/...
@casanovalab.bsky.social
@esidsociety.bsky.social
@casanovalab.bsky.social
@esidsociety.bsky.social
November 19, 2025 at 5:01 PM
In a new research letter, Materna, @vbeziat.bsky.social et al. identified six individuals with homozygous truncating variants in the pre-TCRα intracellular tail, revealing hypomorphic and neutral alleles. rupress.org/jhi/article/...
@casanovalab.bsky.social
@esidsociety.bsky.social
@casanovalab.bsky.social
@esidsociety.bsky.social
Reposted
⏳ Time is running out!
The application deadline for the CIS–Grifols AIM Workshop is November 24.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Don't miss your chance. Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
The application deadline for the CIS–Grifols AIM Workshop is November 24.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Don't miss your chance. Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
November 12, 2025 at 7:54 PM
⏳ Time is running out!
The application deadline for the CIS–Grifols AIM Workshop is November 24.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Don't miss your chance. Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
The application deadline for the CIS–Grifols AIM Workshop is November 24.
Acceptance to the AIM Program comes with:
✈️ Roundtrip airfare
🏨 3 nights lodging
🍽️ All meals
Don't miss your chance. Apply now!
👉 https://clinimmsoc.org/CIS/Meetings/2025-CISGrifols-AIM-Program.htm
Reposted
Ünal, Dublanc, Bustamante, @jrosain.bsky.social et al. @hopitalnecker.bsky.social report two patients with Whipple’s disease caused by autosomal dominant IRF4 deficiency. rupress.org/jhi/article/...
@esidsociety.bsky.social
#InbornErrorsOfImmunity
@esidsociety.bsky.social
#InbornErrorsOfImmunity
November 11, 2025 at 5:02 PM
Ünal, Dublanc, Bustamante, @jrosain.bsky.social et al. @hopitalnecker.bsky.social report two patients with Whipple’s disease caused by autosomal dominant IRF4 deficiency. rupress.org/jhi/article/...
@esidsociety.bsky.social
#InbornErrorsOfImmunity
@esidsociety.bsky.social
#InbornErrorsOfImmunity
Reposted
ORAI1 mutation with mixed loss- and gain-of-function properties causes #immunodeficiency and HLH, say Lucile Noyer (@Lucilenoyer.bsky.social) , Stefan Feske (@stefanfeske.bsky.social) and colleagues (NYU Grossman School of Medicine): rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
November 6, 2025 at 7:45 PM
ORAI1 mutation with mixed loss- and gain-of-function properties causes #immunodeficiency and HLH, say Lucile Noyer (@Lucilenoyer.bsky.social) , Stefan Feske (@stefanfeske.bsky.social) and colleagues (NYU Grossman School of Medicine): rupress.org/jhi/article/...
#InbornErrorsOfImmunity
#InbornErrorsOfImmunity
Reposted
Jeganathan, Pham-Huy et al. @uottawa.ca report that standard newborn screening using T cell receptor excision circles (TRECs) failed to detect delayed-onset ADA deficiency in two cases. But retrospective MS/MS analysis showed diagnostic deoxyadenosine elevation at birth. rupress.org/jhi/article/...
November 10, 2025 at 5:00 PM
Jeganathan, Pham-Huy et al. @uottawa.ca report that standard newborn screening using T cell receptor excision circles (TRECs) failed to detect delayed-onset ADA deficiency in two cases. But retrospective MS/MS analysis showed diagnostic deoxyadenosine elevation at birth. rupress.org/jhi/article/...
Reposted
Nirmatrelvir/ritonavir use reduces risk for #longCOVID in patients with #immunodeficiency. New study from Karen Gilbert, Mei-Sing Ong, Jocelyn Farmer (Lahey Hospital) and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #COVID19 #SARSCoV2
#InbornErrorsOfImmunity #COVID19 #SARSCoV2
November 11, 2025 at 3:45 PM
Nirmatrelvir/ritonavir use reduces risk for #longCOVID in patients with #immunodeficiency. New study from Karen Gilbert, Mei-Sing Ong, Jocelyn Farmer (Lahey Hospital) and colleagues: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #COVID19 #SARSCoV2
#InbornErrorsOfImmunity #COVID19 #SARSCoV2
Reposted
The landscape is changing, and industry collaboration is key. Don't miss your chance to join the CIS–Grifols AIM Program for a Clinical-Industry-Career Development Workshop this January in Austin, TX!
Deadline is November 24th.
👉 https://clinimmsoc.org/CIS/Meetings/2024-CISGrifols-AIM-Program.htm
Deadline is November 24th.
👉 https://clinimmsoc.org/CIS/Meetings/2024-CISGrifols-AIM-Program.htm
November 3, 2025 at 7:01 PM
The landscape is changing, and industry collaboration is key. Don't miss your chance to join the CIS–Grifols AIM Program for a Clinical-Industry-Career Development Workshop this January in Austin, TX!
Deadline is November 24th.
👉 https://clinimmsoc.org/CIS/Meetings/2024-CISGrifols-AIM-Program.htm
Deadline is November 24th.
👉 https://clinimmsoc.org/CIS/Meetings/2024-CISGrifols-AIM-Program.htm
Calling all innovators in clinical immunology!
The Clinical Immunology Society is now accepting abstracts for the 2026 Annual Meeting in New Orleans!
Share your groundbreaking research on a premier stage. Submit today!
🔗 https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#CIS2026
The Clinical Immunology Society is now accepting abstracts for the 2026 Annual Meeting in New Orleans!
Share your groundbreaking research on a premier stage. Submit today!
🔗 https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#CIS2026
November 6, 2025 at 7:01 PM
Calling all innovators in clinical immunology!
The Clinical Immunology Society is now accepting abstracts for the 2026 Annual Meeting in New Orleans!
Share your groundbreaking research on a premier stage. Submit today!
🔗 https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#CIS2026
The Clinical Immunology Society is now accepting abstracts for the 2026 Annual Meeting in New Orleans!
Share your groundbreaking research on a premier stage. Submit today!
🔗 https://cis.clinimmsoc.org/education/meetings/am26/abstracts
#CIS2026
Reposted
A 𝘞𝘈𝘚 promoter variant underlying Wiskott-Aldrich syndrome in two kindreds. New report from Pauline Ober, Christelle Lenoir, Jérémie Rosain @jrosain.bsky.social and collegues @upcite.bsky.social @hopitalnecker.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #Diagnostics
#InbornErrorsOfImmunity #Diagnostics
November 6, 2025 at 2:31 PM
A 𝘞𝘈𝘚 promoter variant underlying Wiskott-Aldrich syndrome in two kindreds. New report from Pauline Ober, Christelle Lenoir, Jérémie Rosain @jrosain.bsky.social and collegues @upcite.bsky.social @hopitalnecker.bsky.social: rupress.org/jhi/article/...
#InbornErrorsOfImmunity #Diagnostics
#InbornErrorsOfImmunity #Diagnostics
Reposted
The systemic effects of 22q11.2 deletion syndrome on immunity. New review from Nicolai van Oers (UT Southwestern) and Kathleen Sullivan (@childrensphila.bsky.social): rupress.org/jhi/article/...
@clinimmsoc.bsky.social
#InbornErrorsOfImmunity #ImmunologicalPhenotypes #TCellDeficiencies
@clinimmsoc.bsky.social
#InbornErrorsOfImmunity #ImmunologicalPhenotypes #TCellDeficiencies
November 6, 2025 at 3:45 PM
The systemic effects of 22q11.2 deletion syndrome on immunity. New review from Nicolai van Oers (UT Southwestern) and Kathleen Sullivan (@childrensphila.bsky.social): rupress.org/jhi/article/...
@clinimmsoc.bsky.social
#InbornErrorsOfImmunity #ImmunologicalPhenotypes #TCellDeficiencies
@clinimmsoc.bsky.social
#InbornErrorsOfImmunity #ImmunologicalPhenotypes #TCellDeficiencies
Reposted
Auto-Abs against type I IFNs: strong, common, and global determinants of severe #arboviral diseases. New review from Adrian Gervais, Alessandro Borghesi (@esibor.bsky.social), Jean-Laurent Casanova (@casanovalab.bsky.social), and Shen-Ying Zhang @inserm.fr: rupress.org/jhi/article/...
October 30, 2025 at 1:45 PM
Auto-Abs against type I IFNs: strong, common, and global determinants of severe #arboviral diseases. New review from Adrian Gervais, Alessandro Borghesi (@esibor.bsky.social), Jean-Laurent Casanova (@casanovalab.bsky.social), and Shen-Ying Zhang @inserm.fr: rupress.org/jhi/article/...
Reposted
Ober, Lenoir, @jrosain.bsky.social et al. report the same ultra-rare pathogenic noncoding single-nucleotide variant in the promoter of WAS in four male patients from two unrelated kindreds w/ features of Wiskott-Aldrich Syndrome. rupress.org/jhi/article/...
@esidsociety.bsky.social
@esidsociety.bsky.social
October 30, 2025 at 4:01 PM
Ober, Lenoir, @jrosain.bsky.social et al. report the same ultra-rare pathogenic noncoding single-nucleotide variant in the promoter of WAS in four male patients from two unrelated kindreds w/ features of Wiskott-Aldrich Syndrome. rupress.org/jhi/article/...
@esidsociety.bsky.social
@esidsociety.bsky.social
Reposted
Noyer, @stefanfeske.bsky.social et al show that a novel mutation in ORAI1 results in constitutive CRAC channel activation while abolishing stimulation-induced channel opening. The mutation is associated with severe immune dysregulation, incl. altered T & NK cell function rupress.org/jhi/article/...
October 30, 2025 at 4:45 PM
Noyer, @stefanfeske.bsky.social et al show that a novel mutation in ORAI1 results in constitutive CRAC channel activation while abolishing stimulation-induced channel opening. The mutation is associated with severe immune dysregulation, incl. altered T & NK cell function rupress.org/jhi/article/...