Clemence 🐀🧠
@clemencegiere.bsky.social
Post-Doctoral Fellow, Saint Louis University, MO, USA | "I'm still not sure what science is. That sounded like performance art." (Fink&Craner, 2017)
Reposted by Clemence 🐀🧠
So excited to share our preprint uncovering FGFR3 autoantibodies as pathogenic drivers of pain sensitization.
Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity.
#PainResearch #Autoimmunity
Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity.
#PainResearch #Autoimmunity
Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy
Sensory neuronopathies (SNN) and small fiber neuropathies (SFN) are debilitating disorders associated with neuropathic pain, yet their underlying mechanisms remain poorly understood. Autoantibodies ag...
www.biorxiv.org
October 9, 2025 at 5:05 PM
So excited to share our preprint uncovering FGFR3 autoantibodies as pathogenic drivers of pain sensitization.
Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity.
#PainResearch #Autoimmunity
Using patient serum, human DRG and rat models, we found that autoantibodies can find FGFR3 on sensory neurons to induce hyperexcitability and hypersensitivity.
#PainResearch #Autoimmunity
my favourite house keeping gene
July 29, 2025 at 3:31 PM
my favourite house keeping gene
“Pain is indeed a reminder of finitude, a claim on our obedience to something outside the self. It makes us an offer we can’t refuse” - Ellen Wayland-Smith
May 2, 2025 at 8:23 PM
“Pain is indeed a reminder of finitude, a claim on our obedience to something outside the self. It makes us an offer we can’t refuse” - Ellen Wayland-Smith
Reposted by Clemence 🐀🧠
Well, maybe the children will have to live with two cures instead of 30 cures.
May 1, 2025 at 3:08 PM
Well, maybe the children will have to live with two cures instead of 30 cures.