Christos Karampelias
ckarampelias.bsky.social
Christos Karampelias
@ckarampelias.bsky.social
Postdocking in Helmholtz Zentrum Munich researching pancreas biology.

Interests: developmental biology, endocrinology, diabetes research, teaching and learning in higher education

Alexander von Humboldt and MSCA fellow
Special thanks to the @embomolmed.org editors and Dr Roth and the peer-reviewers for the constructive feedback! It was a very nice, straightforward and constructive publishing experience :)
Lastly, do not hesitate to reach out for any feedback or plans to collaborate on this work to us!
November 5, 2025 at 7:50 PM
Obviously special shoutout to our great Proteomics and Genomics core facilities at @helmholtzmunich.bsky.social and of course the boss @heikolickert.bsky.social for his continuous support! Grateful to the @humboldt-foundation.de for supporting this work with a postdoctoral fellowship.
November 5, 2025 at 7:50 PM
None of this work would be possible without the contributions of all co-authors: my colleagues Carina, Falk, Mireia and Michi, especially Prof. Kemter and Wolf on the excellent collaboration with the pig model at @lmumuenchen.bsky.social and Dr Kin for his continuous support with the human samples/4
November 5, 2025 at 7:50 PM
Something that was conserved between pig and human systems. This is particularly useful in the context of anti-pancreatic cancer effects of statins as shown in a recent article: www.cell.com/cell-stem-ce... /3
A pancreatic cancer organoid biobank links multi-omics signatures to therapeutic response and clinical evaluation of statin combination therapy
Gao and colleagues identify new therapeutic opportunities for pancreatic cancer via integrated pharmacogenomic analysis of organoid models, highlighting statins as effective agents to overcome chemore...
www.cell.com
November 5, 2025 at 7:50 PM
We show that at least in the pig system there is no difference at the developmental stage that the organoids were derived from. We further validate our system for image-based high content screening applications to show that adrenergic inhibitors and statins can cause toxicity to ducts/2
November 5, 2025 at 7:50 PM