Rosen Lab
@cjrosenlab.bsky.social
Official Acct: Dr. Cliff Rosen's group researching the metabolic & biochemical fate of marrow stromal cells as progenitor osteoblasts & adipocytes at MaineHealth
Congratulations to lab member, Linyi Liu, on his recent promotion to Staff Scientist I! 🎉
November 3, 2025 at 4:44 PM
Congratulations to lab member, Linyi Liu, on his recent promotion to Staff Scientist I! 🎉
Shoutout to our lab manager, Phuong, for representing the Rosen lab in the MHIR Costume Contest and securing first place!! 🥇🎉
October 31, 2025 at 9:33 PM
Shoutout to our lab manager, Phuong, for representing the Rosen lab in the MHIR Costume Contest and securing first place!! 🥇🎉
Happy Halloween from the Rosen lab! @demambrove.bsky.social @carolynchlebek.bsky.social
October 31, 2025 at 8:57 PM
Happy Halloween from the Rosen lab! @demambrove.bsky.social @carolynchlebek.bsky.social
How does calorie restriction change the skeleton in obese mice? Check out our latest paper, out now in Bone. Spoiler: calorie restriction leads to bone loss and shifts the metabolome in the cortex! Congratulations, @carolynchlebek.bsky.social
doi.org/10.1016/j.bo...
doi.org/10.1016/j.bo...
October 29, 2025 at 7:26 PM
How does calorie restriction change the skeleton in obese mice? Check out our latest paper, out now in Bone. Spoiler: calorie restriction leads to bone loss and shifts the metabolome in the cortex! Congratulations, @carolynchlebek.bsky.social
doi.org/10.1016/j.bo...
doi.org/10.1016/j.bo...
New lab photo for the Rosen lab! 📸
October 28, 2025 at 3:35 PM
New lab photo for the Rosen lab! 📸
Earlier this month, medical student Stephanie Lam represented the Rosen lab at the University of New England College of Medicine's Fall Research Forum! Stephanie shared her findings on changes to animal behavior during caloric restriction, generated through her work with @carolynchlebek.bsky.social
October 20, 2025 at 1:26 PM
Earlier this month, medical student Stephanie Lam represented the Rosen lab at the University of New England College of Medicine's Fall Research Forum! Stephanie shared her findings on changes to animal behavior during caloric restriction, generated through her work with @carolynchlebek.bsky.social
We are excited to have Samuel Rubin continue in our lab as a Research Assistant I! Sam started with us as a part-time learner and is now managing an independent research project - go, Sam! Stay tuned to hear about all his exciting research.
September 15, 2025 at 6:36 PM
We are excited to have Samuel Rubin continue in our lab as a Research Assistant I! Sam started with us as a part-time learner and is now managing an independent research project - go, Sam! Stay tuned to hear about all his exciting research.
Lots of fun at #ASBMR2025! We’re excited for another great day! @asbmr.bsky.social
September 7, 2025 at 4:47 PM
Lots of fun at #ASBMR2025! We’re excited for another great day! @asbmr.bsky.social
Huge congrats to lab member @demambrove.bsky.social on a fantastic talk this morning at #ASBMR2025! 🎉🦴 if you didn’t get a chance to ask your question at the session, be sure to find Dr. DeMambro at this meeting! @asbmr.bsky.social
September 5, 2025 at 9:08 PM
Huge congrats to lab member @demambrove.bsky.social on a fantastic talk this morning at #ASBMR2025! 🎉🦴 if you didn’t get a chance to ask your question at the session, be sure to find Dr. DeMambro at this meeting! @asbmr.bsky.social
Huge thanks to @natalieasims.bsky.social for featuring Dr. DeMambro’s abstract during this morning’s session! We are also so excited for this presentation! Join us at noon in Room 6E (TODAY!) #ASBMR2025 @asbmr.bsky.social
September 5, 2025 at 5:48 PM
Huge thanks to @natalieasims.bsky.social for featuring Dr. DeMambro’s abstract during this morning’s session! We are also so excited for this presentation! Join us at noon in Room 6E (TODAY!) #ASBMR2025 @asbmr.bsky.social
Planning out which amazing @asbmr.bsky.social sessions you want to hit tomorrow? Be sure to go to Room 6E tomorrow at noon to hear about treating adult HPP mice with Ilofotase Alfa from @demambrove.bsky.social! (Abstract #1020) Plus so many other great rare bone talks in this session! 🦴
September 5, 2025 at 4:16 AM
Planning out which amazing @asbmr.bsky.social sessions you want to hit tomorrow? Be sure to go to Room 6E tomorrow at noon to hear about treating adult HPP mice with Ilofotase Alfa from @demambrove.bsky.social! (Abstract #1020) Plus so many other great rare bone talks in this session! 🦴
Interested in the role of bone in whole-body energy metabolism? Check out this recent review in @natrevendo.nature.com ! Co-authored by lab leader, Dr. Cliff Rosen 🦴
August 26, 2025 at 4:02 PM
Interested in the role of bone in whole-body energy metabolism? Check out this recent review in @natrevendo.nature.com ! Co-authored by lab leader, Dr. Cliff Rosen 🦴
We love seeing our lab members featured in the MHIR Newsletter! Congrats, again Dr. DeMambro! 🎉
August 12, 2025 at 5:32 PM
We love seeing our lab members featured in the MHIR Newsletter! Congrats, again Dr. DeMambro! 🎉
We are SO excited that Dr. Victoria DeMambro successfully defended her PhD 🎉 Dr. DeMambro’s thesis, entitled “Tissue Nonspecific Alkaline Phosphatase: more than a pro-mineralizing enzyme”, focused on hypophosphatasia 🦴
July 24, 2025 at 1:34 AM
We are SO excited that Dr. Victoria DeMambro successfully defended her PhD 🎉 Dr. DeMambro’s thesis, entitled “Tissue Nonspecific Alkaline Phosphatase: more than a pro-mineralizing enzyme”, focused on hypophosphatasia 🦴
We are SO excited to welcome Dr. Madhura Nijsure @madhura0327.bsky.social to the Rosen lab this week! As a postdoc, she is excited to explore how diet and nutrition influence bone health and homeostasis at the molecular level. Stay tuned for her amazing research!
July 9, 2025 at 6:11 PM
We are SO excited to welcome Dr. Madhura Nijsure @madhura0327.bsky.social to the Rosen lab this week! As a postdoc, she is excited to explore how diet and nutrition influence bone health and homeostasis at the molecular level. Stay tuned for her amazing research!
Looking for a fun Friday read? Check out our most recent paper exploring the inflammatory responses and lipid metabolism in bone marrow adipocytes after high calorie feeding and fasting in humans! Huge congratulations to Dr. Costa & team for such exciting work!
doi.org/10.3389/fend...
doi.org/10.3389/fend...
June 27, 2025 at 1:45 PM
Looking for a fun Friday read? Check out our most recent paper exploring the inflammatory responses and lipid metabolism in bone marrow adipocytes after high calorie feeding and fasting in humans! Huge congratulations to Dr. Costa & team for such exciting work!
doi.org/10.3389/fend...
doi.org/10.3389/fend...
We are excited to welcome #UNECOM student Stephanie Lam to the Rosen lab! Stephanie will be working with @carolynchlebek.bsky.social to understand the effects of calorie restriction on bone and other organ systems.
June 23, 2025 at 6:23 PM
We are excited to welcome #UNECOM student Stephanie Lam to the Rosen lab! Stephanie will be working with @carolynchlebek.bsky.social to understand the effects of calorie restriction on bone and other organ systems.
Congratulations to the @asbmr.bsky.social Harold M. Frost Young Investigator Award recipients! We are excited to see our own @carolynchlebek.bsky.social among the awardees 🎉 Attend the @orssociety.bsky.social Musculoskeletal Biology Workshop to hear from the awardees about their exciting research!
June 18, 2025 at 1:38 PM
Congratulations to the @asbmr.bsky.social Harold M. Frost Young Investigator Award recipients! We are excited to see our own @carolynchlebek.bsky.social among the awardees 🎉 Attend the @orssociety.bsky.social Musculoskeletal Biology Workshop to hear from the awardees about their exciting research!
Last week, we said goodbye to Dr. Costa, but we cannot wait to hear about her amazing postdoctoral research ahead at the University of Pittsburgh! Congratulations again to Dr. Costa on a fantastic thesis and research career at MaineHealth! You will be missed!
June 16, 2025 at 5:05 PM
Last week, we said goodbye to Dr. Costa, but we cannot wait to hear about her amazing postdoctoral research ahead at the University of Pittsburgh! Congratulations again to Dr. Costa on a fantastic thesis and research career at MaineHealth! You will be missed!
Curious about how follicle-stimulating hormone FSH contributes to the development of osteoporosis, obesity, and cognitive decline? Check out this recent review published in @cp-trendsmolecmed.bsky.social
www.cell.com/trends/molec...
www.cell.com/trends/molec...
June 11, 2025 at 2:45 PM
Curious about how follicle-stimulating hormone FSH contributes to the development of osteoporosis, obesity, and cognitive decline? Check out this recent review published in @cp-trendsmolecmed.bsky.social
www.cell.com/trends/molec...
www.cell.com/trends/molec...
Have you ever dreamed of isolating primary bone marrow adipocytes but were unsure of how? Check out our recent chapter in Bone Research Protocols detailing the isolation! Huge congrats to lead author, Dr. Samantha Costa! doi.org/10.1007/978-...
June 6, 2025 at 7:04 PM
Have you ever dreamed of isolating primary bone marrow adipocytes but were unsure of how? Check out our recent chapter in Bone Research Protocols detailing the isolation! Huge congrats to lead author, Dr. Samantha Costa! doi.org/10.1007/978-...
The Rosen lab successes continue flowing in! Shoutout to UNE Medical Student James Gray, who was recently awarded the Kahn Family Research Fellowship. James will be investigating the brain-bone connection in the context of spaceflight health, working with postdoc @carolynchlebek.bsky.social 🧠🦴👨🚀👩🚀
April 25, 2025 at 2:35 PM
The Rosen lab successes continue flowing in! Shoutout to UNE Medical Student James Gray, who was recently awarded the Kahn Family Research Fellowship. James will be investigating the brain-bone connection in the context of spaceflight health, working with postdoc @carolynchlebek.bsky.social 🧠🦴👨🚀👩🚀
Huge congratulations to Dr. Samantha Costa, who placed 1st in the Fast Pitch Graduate Student Showcase through the Bioscience Association of Maine! 🎉 and right of the heels of a successful thesis defense!
April 23, 2025 at 12:41 PM
Huge congratulations to Dr. Samantha Costa, who placed 1st in the Fast Pitch Graduate Student Showcase through the Bioscience Association of Maine! 🎉 and right of the heels of a successful thesis defense!
We are SO excited that Dr. Samantha Costa successfully defended her PhD 🎉 Dr. Costa’s thesis, entitled “The New Obesity Paradox: How bone marrow immunosuppression leads to obesity-related bone loss and peripheral inflammation”, includes a wealth of exciting data that we will share here soon! 🦴
April 21, 2025 at 3:44 PM
We are SO excited that Dr. Samantha Costa successfully defended her PhD 🎉 Dr. Costa’s thesis, entitled “The New Obesity Paradox: How bone marrow immunosuppression leads to obesity-related bone loss and peripheral inflammation”, includes a wealth of exciting data that we will share here soon! 🦴