Cincinnati Children's CBDI
@cincychildrenscbdi.bsky.social
We are the Cancer & Blood Diseases Institute at Cincinnati Children's Hospital. Proudly ranked as the #1 cancer program in the country by U.S. News & World Report.
Observed annually on Nov. 11, Veterans Day is an opportunity to recognize the bravery of all our U.S. Military Veterans and the sacrifices they’ve made. ♥️
November 11, 2025 at 5:27 PM
Observed annually on Nov. 11, Veterans Day is an opportunity to recognize the bravery of all our U.S. Military Veterans and the sacrifices they’ve made. ♥️
Reposted by Cincinnati Children's CBDI
Congrats to Lee Grimes, Nathan Salomonis and colleagues @cincychildrens.bsky.social for their latest publication in #NatureImmunology shedding new light on how #BoneMarrow produces blood cells. www.nature.com/articles/s41...
A unified multimodal single-cell framework reveals a discrete state model of hematopoiesis in mice - Nature Immunology
Grimes and colleagues integrate multiomic features to create a framework that allows the isolation of discrete cell states across hematopoiesis and exploit the underlying gene regulatory networks to i...
www.nature.com
October 22, 2025 at 9:18 AM
Congrats to Lee Grimes, Nathan Salomonis and colleagues @cincychildrens.bsky.social for their latest publication in #NatureImmunology shedding new light on how #BoneMarrow produces blood cells. www.nature.com/articles/s41...
Our CBDI teams had a spooktacular time celebrating Halloween today. An extra special shoutout to Susan Council, our Outpatient Clinical Manager, for 30 incredible years of service! 👏🎃
October 31, 2025 at 6:54 PM
Our CBDI teams had a spooktacular time celebrating Halloween today. An extra special shoutout to Susan Council, our Outpatient Clinical Manager, for 30 incredible years of service! 👏🎃
Reposted by Cincinnati Children's CBDI
Making ‘Cold’ Tumors Sensitive Again: In mice, rapamycin re-sensitizes tumors with RAC1 A159V mutations to immune checkpoint inhibitors. Early findings offer rationale for combination therapy.
Study: www.science.org/doi/10.1126/...
Blog summary:
scienceblog.cincinnatichildrens.org/hot-new-clue...
Study: www.science.org/doi/10.1126/...
Blog summary:
scienceblog.cincinnatichildrens.org/hot-new-clue...
Hot New Clues for Treating Immune 'Cold' Tumors - Research Horizons
scienceblog.cincinnatichildrens.org
October 29, 2025 at 6:48 PM
Making ‘Cold’ Tumors Sensitive Again: In mice, rapamycin re-sensitizes tumors with RAC1 A159V mutations to immune checkpoint inhibitors. Early findings offer rationale for combination therapy.
Study: www.science.org/doi/10.1126/...
Blog summary:
scienceblog.cincinnatichildrens.org/hot-new-clue...
Study: www.science.org/doi/10.1126/...
Blog summary:
scienceblog.cincinnatichildrens.org/hot-new-clue...
A study led by Mingjun Cai and Yi Zheng, PhD, reveals how a tumor mutation blocks immune checkpoint inhibitors, and shows a way to make the tumors sensitive again. Learn more: scienceblog.cincinnatichildrens.org/hot-new-clue...
Hot New Clues for Treating Immune 'Cold' Tumors - Research Horizons
scienceblog.cincinnatichildrens.org
October 30, 2025 at 1:53 PM
A study led by Mingjun Cai and Yi Zheng, PhD, reveals how a tumor mutation blocks immune checkpoint inhibitors, and shows a way to make the tumors sensitive again. Learn more: scienceblog.cincinnatichildrens.org/hot-new-clue...
Researchers from our team are rethinking how bone marrow works. Learn more: scienceblog.cincinnatichildrens.org/rethinking-h...
Rethinking How Bone Marrow Works - Research Horizons
scienceblog.cincinnatichildrens.org
October 24, 2025 at 7:03 PM
Researchers from our team are rethinking how bone marrow works. Learn more: scienceblog.cincinnatichildrens.org/rethinking-h...
For the third year in a row, we’re honored to be ranked #1 in the nation for Pediatric Cancer Care. 🎗️💛
October 7, 2025 at 6:52 PM
For the third year in a row, we’re honored to be ranked #1 in the nation for Pediatric Cancer Care. 🎗️💛
Reposted by Cincinnati Children's CBDI
For the 16th year in a row, we’ve earned a spot on the Best Children’s Hospitals Honor Roll by U.S. News & World Report! We’re proud to be ranked #1 in the nation for: Pediatric Cancer Care, Gastroenterology & GI Surgery and Diabetes & Endocrinology.
October 7, 2025 at 4:16 AM
For the 16th year in a row, we’ve earned a spot on the Best Children’s Hospitals Honor Roll by U.S. News & World Report! We’re proud to be ranked #1 in the nation for: Pediatric Cancer Care, Gastroenterology & GI Surgery and Diabetes & Endocrinology.
We are honored to receive a $500,000 grant from Hyundai Hope On Wheels 🎗️
Hyundai Hope On Wheels presented $500,000 in grants to support our work in pediatric cancer research and care. The grants were awarded during a Handprint Ceremony, where children placed their painted handprints on a Hyundai vehicle — a symbol of their strength, courage, and hope for a cure.
September 30, 2025 at 5:05 PM
We are honored to receive a $500,000 grant from Hyundai Hope On Wheels 🎗️
Reposted by Cincinnati Children's CBDI
Kids facing cancer show us what it means to fight—and to thrive. Their stories of strength and hope remind us why awareness and research matter. This #ChildhoodCancerAwarenessMonth, we honor them and stand with every family impacted by cancer.
More:
www.cincinnatichildrens.org/service/c/ca...
More:
www.cincinnatichildrens.org/service/c/ca...
September 16, 2025 at 4:20 PM
Kids facing cancer show us what it means to fight—and to thrive. Their stories of strength and hope remind us why awareness and research matter. This #ChildhoodCancerAwarenessMonth, we honor them and stand with every family impacted by cancer.
More:
www.cincinnatichildrens.org/service/c/ca...
More:
www.cincinnatichildrens.org/service/c/ca...
Reposted by Cincinnati Children's CBDI
In the Spotlight: What began as a suspected stomach bug turned into a life-threatening diagnosis for 6-year-old Ronomy. After weeks of misdiagnoses, a second opinion at Cincinnati Children's revealed a brain tumor—leading to life-saving surgery.
www.whas11.com/article/news...
www.whas11.com/article/news...
Jeffersonville parents push for second opinion before 6-year-old is diagnosed with brain tumor
A Jeffersonville family's persistence led to their son's life-saving brain surgery after initial misdiagnoses.
www.whas11.com
September 17, 2025 at 1:38 PM
In the Spotlight: What began as a suspected stomach bug turned into a life-threatening diagnosis for 6-year-old Ronomy. After weeks of misdiagnoses, a second opinion at Cincinnati Children's revealed a brain tumor—leading to life-saving surgery.
www.whas11.com/article/news...
www.whas11.com/article/news...
Reposted by Cincinnati Children's CBDI
Did you know sickle cell disease is the most common severe genetic blood disorder in the U.S.? During Sickle Cell Awareness Month, learn more about this condition and the people in your community it affects: blog.cincinnatichildrens.org/rare-and-com.... #SickleCell #SickleCellAwarenessMonth
Four Important Things to Know About Sickle Cell Disease
Sickle cell disease is the most common genetic blood disorder in the United States. It is also often misunderstood. Learn four things about sickle cell and the people it affects.
blog.cincinnatichildrens.org
September 10, 2025 at 12:24 PM
Did you know sickle cell disease is the most common severe genetic blood disorder in the U.S.? During Sickle Cell Awareness Month, learn more about this condition and the people in your community it affects: blog.cincinnatichildrens.org/rare-and-com.... #SickleCell #SickleCellAwarenessMonth
Reposted by Cincinnati Children's CBDI
🎗️ As we begin #ChildhoodCancerAwarenessMonth, we’d like to introduce you to Harper — a brave young girl whose cancer journey reminds us of the strength and resilience children show in the face of unimaginable challenges. www.cincinnatichildrens.org/service/s/su...
September 1, 2025 at 10:37 PM
🎗️ As we begin #ChildhoodCancerAwarenessMonth, we’d like to introduce you to Harper — a brave young girl whose cancer journey reminds us of the strength and resilience children show in the face of unimaginable challenges. www.cincinnatichildrens.org/service/s/su...
Today marks 9 years since our Proton Therapy Center opened! We've made major strides, like completing the first FLASH clinical trial. Stories like Atticus’s, who received proton therapy for brain cancer, remind us why this work is so important. Learn more: youtu.be/siC7bs7ziuE?...
Atticus the Great | Cincinnati Children's
YouTube video by Cincinnati Children's
youtu.be
August 8, 2025 at 1:44 PM
Today marks 9 years since our Proton Therapy Center opened! We've made major strides, like completing the first FLASH clinical trial. Stories like Atticus’s, who received proton therapy for brain cancer, remind us why this work is so important. Learn more: youtu.be/siC7bs7ziuE?...
Reposted by Cincinnati Children's CBDI
In a segment airing nationwide on @pbs.org, Dr. Michael Jordan sheds light on Hemophagocytic Lymphohistiocytosis (HLH)—a rare and life-threatening immune disorder. 💙
📺 Watch: medicalstories.tv/title/hlh/
📺 Watch: medicalstories.tv/title/hlh/
HLH | Medical Stories
Easton had HLH, despite being under a year old. Kayla and Eric were enjoying their time as parents until his health took a turn for the worse.
medicalstories.tv
July 8, 2025 at 1:43 PM
In a segment airing nationwide on @pbs.org, Dr. Michael Jordan sheds light on Hemophagocytic Lymphohistiocytosis (HLH)—a rare and life-threatening immune disorder. 💙
📺 Watch: medicalstories.tv/title/hlh/
📺 Watch: medicalstories.tv/title/hlh/
Reposted by Cincinnati Children's CBDI
"This study demonstrates that #IRAK4 is a therapeutic target in #AML."
Congrats to Dr. Starczynowski and colleagues @cincychildrenscbdi.bsky.social #CincinnatChildrens #CincyKidsScience
www.nature.com/articles/s41...
Congrats to Dr. Starczynowski and colleagues @cincychildrenscbdi.bsky.social #CincinnatChildrens #CincyKidsScience
www.nature.com/articles/s41...
Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization - Leukemia
Leukemia - Targeting of IRAK4 and GSPT1 enhances therapeutic efficacy in AML via c-Myc destabilization
www.nature.com
July 23, 2025 at 3:14 PM
"This study demonstrates that #IRAK4 is a therapeutic target in #AML."
Congrats to Dr. Starczynowski and colleagues @cincychildrenscbdi.bsky.social #CincinnatChildrens #CincyKidsScience
www.nature.com/articles/s41...
Congrats to Dr. Starczynowski and colleagues @cincychildrenscbdi.bsky.social #CincinnatChildrens #CincyKidsScience
www.nature.com/articles/s41...
Reposted by Cincinnati Children's CBDI
75 years after the discovery of HbSC type #SickleCellDisease, the field finally has a mouse model to advance care for millions of people with this disease around the world
Very proud to be a part of the @cincychildrenscbdi.bsky.social #sicklecell center
pubmed.ncbi.nlm.nih.gov/40324066/
Very proud to be a part of the @cincychildrenscbdi.bsky.social #sicklecell center
pubmed.ncbi.nlm.nih.gov/40324066/
A novel mouse model of hemoglobin SC disease reveals mechanisms underlying beneficial effects of hydroxyurea - PubMed
Sickle cell hemoglobin C (HbSC) disease results from compound heterozygosity of hemoglobin S (HbS) and hemoglobin C (HbC), comprising 30% of sickle cell disease (SCD). HbC induces red blood cell (RBC)...
pubmed.ncbi.nlm.nih.gov
July 10, 2025 at 8:21 PM
75 years after the discovery of HbSC type #SickleCellDisease, the field finally has a mouse model to advance care for millions of people with this disease around the world
Very proud to be a part of the @cincychildrenscbdi.bsky.social #sicklecell center
pubmed.ncbi.nlm.nih.gov/40324066/
Very proud to be a part of the @cincychildrenscbdi.bsky.social #sicklecell center
pubmed.ncbi.nlm.nih.gov/40324066/
Tune in to Cincinnati Children's Applied Gene and Cell Therapy Center "Meet the Expert Series" on Friday, July 18 from 12pm-1pm. Register here: cvent.me/BPa5o5.
July 10, 2025 at 7:16 PM
Tune in to Cincinnati Children's Applied Gene and Cell Therapy Center "Meet the Expert Series" on Friday, July 18 from 12pm-1pm. Register here: cvent.me/BPa5o5.
Reposted by Cincinnati Children's CBDI
Our 2024 Research Annual Report is live! Learn how experts @cincychildrens.bsky.social @cincykidsheart.bsky.social @cincykidsrad.bsky.social and more are improving #childhealth fueled by $308M in #research funding. #RAR24 #MedSky #PedsSky #SciSky scienceblog.cincinnatichildrens.org/explore-our-...
May 7, 2025 at 2:00 PM
Our 2024 Research Annual Report is live! Learn how experts @cincychildrens.bsky.social @cincykidsheart.bsky.social @cincykidsrad.bsky.social and more are improving #childhealth fueled by $308M in #research funding. #RAR24 #MedSky #PedsSky #SciSky scienceblog.cincinnatichildrens.org/explore-our-...
Join us for the first session of the AGCTC Forum: Meet the Expert, presented by Cincinnati Children’s Applied Gene and Cell Therapy Center. This new webinar series kicks off on Monday, June 9, 2025, from 12:00 PM to 1:00 PM EST. Register here: cvent.me/L1r815
#AGCTCForum
#AGCTCForum
May 15, 2025 at 5:06 PM
Join us for the first session of the AGCTC Forum: Meet the Expert, presented by Cincinnati Children’s Applied Gene and Cell Therapy Center. This new webinar series kicks off on Monday, June 9, 2025, from 12:00 PM to 1:00 PM EST. Register here: cvent.me/L1r815
#AGCTCForum
#AGCTCForum
How bacteria in our aging guts can elevate risk of leukemia and perhaps more. Learn here: scienceblog.cincinnatichildrens.org/how-bacteria...
How Bacteria in Our Aging Guts Can Elevate Risk of Leukemia and Perhaps More - Research Horizons
scienceblog.cincinnatichildrens.org
April 23, 2025 at 6:07 PM
How bacteria in our aging guts can elevate risk of leukemia and perhaps more. Learn here: scienceblog.cincinnatichildrens.org/how-bacteria...
#WorldHemophiliaDay was on April 17! Our Family Resource Center was lit red from April 16-18 to honor and support those with hemophilia and inherited bleeding disorders. Learn more about our Hemophilia Treatment Center: www.cincinnatichildrens.org/health/h/hem...
@cincychildrens.bsky.social
@cincychildrens.bsky.social
April 21, 2025 at 7:59 PM
#WorldHemophiliaDay was on April 17! Our Family Resource Center was lit red from April 16-18 to honor and support those with hemophilia and inherited bleeding disorders. Learn more about our Hemophilia Treatment Center: www.cincinnatichildrens.org/health/h/hem...
@cincychildrens.bsky.social
@cincychildrens.bsky.social
First gene therapy trial for telomere biology disorders shows promising results. Learn more: scienceblog.cincinnatichildrens.org/first-gene-t...
First Gene Therapy Trial for Telomere Biology Disorders Shows Promising Results - Research Horizons
scienceblog.cincinnatichildrens.org
February 27, 2025 at 6:59 PM
First gene therapy trial for telomere biology disorders shows promising results. Learn more: scienceblog.cincinnatichildrens.org/first-gene-t...
Cincinnati Children's is hosting a blood drive on Friday, March 28, from 7 am-1 pm, in Sabin Auditorium. Please consider donating Platelets or Double Red Cells.
All donors will receive a UC Bearcat Blanket. Schedule your appointment: donateblood.uc.edu/donor/schedu....
All donors will receive a UC Bearcat Blanket. Schedule your appointment: donateblood.uc.edu/donor/schedu....
February 12, 2025 at 7:48 PM
Cincinnati Children's is hosting a blood drive on Friday, March 28, from 7 am-1 pm, in Sabin Auditorium. Please consider donating Platelets or Double Red Cells.
All donors will receive a UC Bearcat Blanket. Schedule your appointment: donateblood.uc.edu/donor/schedu....
All donors will receive a UC Bearcat Blanket. Schedule your appointment: donateblood.uc.edu/donor/schedu....
At @cincychildrens.bsky.social, we are changing the outcome together. Watch this video about our best in class research shared facilities. www.youtube.com/watch?featur...
Shared Research Facilities 2024 | Cincinnati Children's
YouTube video by Cincinnati Children's
www.youtube.com
January 21, 2025 at 8:54 PM
At @cincychildrens.bsky.social, we are changing the outcome together. Watch this video about our best in class research shared facilities. www.youtube.com/watch?featur...